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Article: Orthopedic applications of gene therapy

TitleOrthopedic applications of gene therapy
Authors
KeywordsBone induction
Gene therapy
Spinal fusion
Issue Date2001
PublisherSpringer Japan. The Journal's web site is located at http://link.springer.de/link/service/journals/00776/index.htm
Citation
Journal Of Orthopaedic Science, 2001, v. 6 n. 2, p. 199-207 How to Cite?
AbstractA literature review of the applications of gene therapy for the treatment of orthopedic disorders was conducted, and showed that gene therapy provides us with new possibilities for the clinical management of orthopedic disorders. Most of these disorders, such as failure to obtain spinal fusion, disc degeneration, fracture and segmental bone defects, bone tumor, articular disorders, soft-tissue injury, genetic disorders, and nerve and muscular disorders, are difficult to treat by traditional surgical or medical means, and are under investigation for gene therapy. Many rapid advances have been made in the field of this novel approach. Although a number of obstacles remain to be solved before gene therapy can be applied for clinical use in humans, it is already apparent that gene therapy has the great potential of becoming a valuable clinical treatment for orthopedic disorders in the twenty-first century. With the development of gene transfer techniques, gene therapy will probably have numerous applications in orthopedic disorders.
Persistent Identifierhttp://hdl.handle.net/10722/92059
ISSN
2015 Impact Factor: 1.154
2015 SCImago Journal Rankings: 0.708
References

 

DC FieldValueLanguage
dc.contributor.authorChen, Yen_HK
dc.date.accessioned2010-09-17T10:34:52Z-
dc.date.available2010-09-17T10:34:52Z-
dc.date.issued2001en_HK
dc.identifier.citationJournal Of Orthopaedic Science, 2001, v. 6 n. 2, p. 199-207en_HK
dc.identifier.issn0949-2658en_HK
dc.identifier.urihttp://hdl.handle.net/10722/92059-
dc.description.abstractA literature review of the applications of gene therapy for the treatment of orthopedic disorders was conducted, and showed that gene therapy provides us with new possibilities for the clinical management of orthopedic disorders. Most of these disorders, such as failure to obtain spinal fusion, disc degeneration, fracture and segmental bone defects, bone tumor, articular disorders, soft-tissue injury, genetic disorders, and nerve and muscular disorders, are difficult to treat by traditional surgical or medical means, and are under investigation for gene therapy. Many rapid advances have been made in the field of this novel approach. Although a number of obstacles remain to be solved before gene therapy can be applied for clinical use in humans, it is already apparent that gene therapy has the great potential of becoming a valuable clinical treatment for orthopedic disorders in the twenty-first century. With the development of gene transfer techniques, gene therapy will probably have numerous applications in orthopedic disorders.en_HK
dc.languageengen_HK
dc.publisherSpringer Japan. The Journal's web site is located at http://link.springer.de/link/service/journals/00776/index.htmen_HK
dc.relation.ispartofJournal of Orthopaedic Scienceen_HK
dc.subjectBone inductionen_HK
dc.subjectGene therapyen_HK
dc.subjectSpinal fusionen_HK
dc.titleOrthopedic applications of gene therapyen_HK
dc.typeArticleen_HK
dc.identifier.emailChen, Y:ychenc@hkucc.hku.hken_HK
dc.identifier.authorityChen, Y=rp01318en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s007760100072en_HK
dc.identifier.pmid11484110en_HK
dc.identifier.scopuseid_2-s2.0-0035059059en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0035059059&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume6en_HK
dc.identifier.issue2en_HK
dc.identifier.spage199en_HK
dc.identifier.epage207en_HK
dc.publisher.placeJapanen_HK
dc.identifier.scopusauthoridChen, Y=36463185300en_HK

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