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Article: Quality-of-life in DDDR pacing: Atrioventricular synchrony or rate adaptation?

TitleQuality-of-life in DDDR pacing: Atrioventricular synchrony or rate adaptation?
Authors
Issue Date1994
PublisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0147-8389&site=1
Citation
Pace - Pacing And Clinical Electrophysiology, 1994, v. 17 n. 11 II, p. 1838-1843 How to Cite?
AbstractAlthough differences in exercise performance have been observed between different rate adaptive modes, the relative impact of atrioventricular (AV) synchrony and rate adaptation on quality of life (QOL) have not been determined. Thirty-three patients with either sinoatrial disease (18) or complete atrioventricular (AV) block (15) received DDDR pacemakers (16 minute ventilation sensing, 17 activity sensing). There were 11 males and 22 females, with a mean age of 66 ± 1 (range 39-78) years. The study was a double-blind, triple cross-over study comparing DDDR, DDD, and VVIR modes. At the end of each 8-week study period in each mode. QOL was assessed by a questionnaire evaluating patients functional class (Classes I-IV), physical malaise inventory (41 items), illness perception (43 items), and overall QOL rating based on a 48 items measure covering different aspects of the patients daily life adjustment. Two patients required early crossover from VVIR mode during the study. Patients experienced significantly fewer physical malaise such as temperature intolerance, dyspnea, and palpitations in the DDDR mode, compared with either DDD or VVIR pacing, DDDR pacing reduced the perception of illness in 5 of 43 items compared to VVIR pacing, and improved stamina and appetite compared to DDD pacing. The overall QOL score was 102 ± 2, 105 ± 2, 113 ± 2 in the DDDR, DDD, and VVIR modes, respectively, with a higher score indicating a poorer QOL (DDDR/DDD vs VVIR, P < 0.02). There was no change in functional classes between the three pacing modes. In conclusion, VVIR pacing has a lower QOL compared with DDD pacing, which can be further enhanced with rate augmentation.
Persistent Identifierhttp://hdl.handle.net/10722/91661
ISSN
2015 Impact Factor: 1.156
2015 SCImago Journal Rankings: 0.662
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLau, CPen_HK
dc.contributor.authorTai, YTen_HK
dc.contributor.authorLee, PWHen_HK
dc.contributor.authorCheung, Ben_HK
dc.contributor.authorTang, MOen_HK
dc.contributor.authorLam, WKen_HK
dc.date.accessioned2010-09-17T10:22:57Z-
dc.date.available2010-09-17T10:22:57Z-
dc.date.issued1994en_HK
dc.identifier.citationPace - Pacing And Clinical Electrophysiology, 1994, v. 17 n. 11 II, p. 1838-1843en_HK
dc.identifier.issn0147-8389en_HK
dc.identifier.urihttp://hdl.handle.net/10722/91661-
dc.description.abstractAlthough differences in exercise performance have been observed between different rate adaptive modes, the relative impact of atrioventricular (AV) synchrony and rate adaptation on quality of life (QOL) have not been determined. Thirty-three patients with either sinoatrial disease (18) or complete atrioventricular (AV) block (15) received DDDR pacemakers (16 minute ventilation sensing, 17 activity sensing). There were 11 males and 22 females, with a mean age of 66 ± 1 (range 39-78) years. The study was a double-blind, triple cross-over study comparing DDDR, DDD, and VVIR modes. At the end of each 8-week study period in each mode. QOL was assessed by a questionnaire evaluating patients functional class (Classes I-IV), physical malaise inventory (41 items), illness perception (43 items), and overall QOL rating based on a 48 items measure covering different aspects of the patients daily life adjustment. Two patients required early crossover from VVIR mode during the study. Patients experienced significantly fewer physical malaise such as temperature intolerance, dyspnea, and palpitations in the DDDR mode, compared with either DDD or VVIR pacing, DDDR pacing reduced the perception of illness in 5 of 43 items compared to VVIR pacing, and improved stamina and appetite compared to DDD pacing. The overall QOL score was 102 ± 2, 105 ± 2, 113 ± 2 in the DDDR, DDD, and VVIR modes, respectively, with a higher score indicating a poorer QOL (DDDR/DDD vs VVIR, P < 0.02). There was no change in functional classes between the three pacing modes. In conclusion, VVIR pacing has a lower QOL compared with DDD pacing, which can be further enhanced with rate augmentation.en_HK
dc.languageengen_HK
dc.publisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0147-8389&site=1en_HK
dc.relation.ispartofPACE - Pacing and Clinical Electrophysiologyen_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshAtrioventricular Node - physiopathologyen_HK
dc.subject.meshCardiac Pacing, Artificial - adverse effects - methodsen_HK
dc.subject.meshCross-Over Studiesen_HK
dc.subject.meshDouble-Blind Methoden_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHeart Block - physiopathology - therapyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshQuality of Lifeen_HK
dc.subject.meshSinoatrial Block - physiopathology - therapyen_HK
dc.titleQuality-of-life in DDDR pacing: Atrioventricular synchrony or rate adaptation?en_HK
dc.typeArticleen_HK
dc.identifier.emailCheung, B:mycheung@hku.hken_HK
dc.identifier.authorityCheung, B=rp01321en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1540-8159.1994.tb03759.xen_HK
dc.identifier.pmid7845777en_HK
dc.identifier.scopuseid_2-s2.0-0028034012en_HK
dc.identifier.volume17en_HK
dc.identifier.issue11 IIen_HK
dc.identifier.spage1838en_HK
dc.identifier.epage1843en_HK
dc.identifier.isiWOS:A1994PR12400002-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLau, CP=7401968501en_HK
dc.identifier.scopusauthoridTai, YT=7201916438en_HK
dc.identifier.scopusauthoridLee, PWH=7406120357en_HK
dc.identifier.scopusauthoridCheung, B=7103294806en_HK
dc.identifier.scopusauthoridTang, MO=7401973887en_HK
dc.identifier.scopusauthoridLam, WK=7203021937en_HK

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