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Article: Utilization of lipid lowering medications among adults in the United States 1999-2006

TitleUtilization of lipid lowering medications among adults in the United States 1999-2006
Authors
KeywordsCoronary heart disease
Diabetes
Dyslipidemia
Lipid lowering medication
Statins
Issue Date2010
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/atherosclerosis
Citation
Atherosclerosis, 2010, v. 208 n. 2, p. 456-460 How to Cite?
AbstractObjective: We examined the use of lipid lowering medications and control of dyslipidemia among US adults in 1999-2006. Methods: Data were extracted from the National Health and Nutrition Examination Survey 1999-2006. Results: The mean low-density lipoprotein-cholesterol (LDL-C) level significantly decreased from 3.25 ± 0.03 mmol/L in 1999-2002 to 3.02 ± 0.02 mmol/L in 2003-2006 in men, and from 3.11 ± 0.03 to 2.98 ± 0.03 mmol/L in women (p < 0.001). Statins and fibrates were the most commonly used medications. Among those diagnosed with hypercholesterolemia, the proportion on treatment increased from 32.4% to 38.9% (p = 0.001) in the 8-year period. The proportion of participants with a history of diabetes treated with a statin increased from 20.9 ± 2.2% in 1999-2002 to 37.6 ± 2.5% in 2003-2006 (p < 0.001). However, only 39.9% of people with diabetes and 45.4% of people with ischemic heart disease (IHD) achieved LDL-C target levels. Conclusions: Between 1999 and 2006, LDL-C level decreased in US adults and use of lipid lowering medications increased. More effort is still needed to detect and treat dyslipidemia in the community, particularly in people at high cardiovascular risk. © 2009 Elsevier Ireland Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/91632
ISSN
2015 Impact Factor: 3.942
2015 SCImago Journal Rankings: 1.819
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLi, Men_HK
dc.contributor.authorOng, KLen_HK
dc.contributor.authorTse, HFen_HK
dc.contributor.authorCheung, BMYen_HK
dc.date.accessioned2010-09-17T10:22:30Z-
dc.date.available2010-09-17T10:22:30Z-
dc.date.issued2010en_HK
dc.identifier.citationAtherosclerosis, 2010, v. 208 n. 2, p. 456-460en_HK
dc.identifier.issn0021-9150en_HK
dc.identifier.urihttp://hdl.handle.net/10722/91632-
dc.description.abstractObjective: We examined the use of lipid lowering medications and control of dyslipidemia among US adults in 1999-2006. Methods: Data were extracted from the National Health and Nutrition Examination Survey 1999-2006. Results: The mean low-density lipoprotein-cholesterol (LDL-C) level significantly decreased from 3.25 ± 0.03 mmol/L in 1999-2002 to 3.02 ± 0.02 mmol/L in 2003-2006 in men, and from 3.11 ± 0.03 to 2.98 ± 0.03 mmol/L in women (p < 0.001). Statins and fibrates were the most commonly used medications. Among those diagnosed with hypercholesterolemia, the proportion on treatment increased from 32.4% to 38.9% (p = 0.001) in the 8-year period. The proportion of participants with a history of diabetes treated with a statin increased from 20.9 ± 2.2% in 1999-2002 to 37.6 ± 2.5% in 2003-2006 (p < 0.001). However, only 39.9% of people with diabetes and 45.4% of people with ischemic heart disease (IHD) achieved LDL-C target levels. Conclusions: Between 1999 and 2006, LDL-C level decreased in US adults and use of lipid lowering medications increased. More effort is still needed to detect and treat dyslipidemia in the community, particularly in people at high cardiovascular risk. © 2009 Elsevier Ireland Ltd. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/atherosclerosisen_HK
dc.relation.ispartofAtherosclerosisen_HK
dc.subjectCoronary heart diseaseen_HK
dc.subjectDiabetesen_HK
dc.subjectDyslipidemiaen_HK
dc.subjectLipid lowering medicationen_HK
dc.subjectStatinsen_HK
dc.subject.meshAdult-
dc.subject.meshDyslipidemias - drug therapy - epidemiology-
dc.subject.meshHydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use-
dc.subject.meshHypercholesterolemia - drug therapy - epidemiology-
dc.subject.meshHypolipidemic Agents - therapeutic use-
dc.titleUtilization of lipid lowering medications among adults in the United States 1999-2006en_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0021-9150&volume=208&issue=2&spage=456&epage=460&date=2010&atitle=Utilization+of+lipid+lowering+medications+among+adults+in+the+United+States+1999-2006-
dc.identifier.emailTse, HF:hftse@hkucc.hku.hken_HK
dc.identifier.emailCheung, BMY:mycheung@hku.hken_HK
dc.identifier.authorityTse, HF=rp00428en_HK
dc.identifier.authorityCheung, BMY=rp01321en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.atherosclerosis.2009.08.001en_HK
dc.identifier.pmid19700160-
dc.identifier.scopuseid_2-s2.0-74749095536en_HK
dc.identifier.hkuros180000-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-74749095536&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume208en_HK
dc.identifier.issue2en_HK
dc.identifier.spage456en_HK
dc.identifier.epage460en_HK
dc.identifier.isiWOS:000273989200028-
dc.publisher.placeIrelanden_HK
dc.identifier.scopusauthoridLi, M=26661782700en_HK
dc.identifier.scopusauthoridOng, KL=8340854000en_HK
dc.identifier.scopusauthoridTse, HF=7006070805en_HK
dc.identifier.scopusauthoridCheung, BMY=7103294806en_HK
dc.identifier.citeulike5457791-

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