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Article: Cryptococcal meningitis presenting concurrently with systemic lupus erythematosus

TitleCryptococcal meningitis presenting concurrently with systemic lupus erythematosus
Authors
KeywordsCryptococcaemia
Cryptococcal meningitis
Fungal infection
Lupus
Issue Date1998
PublisherPacini Editore SpA. The Journal's web site is located at http://www.clinexprheumatol.org
Citation
Clinical And Experimental Rheumatology, 1998, v. 16 n. 2, p. 169-171 How to Cite?
AbstractCryptococcal meningitis is a rare but well recognized complication of systemic lupus erythematosus (SLE). Since in all previously reported cases in the medical literature the patients developed this opportunistic infection as the result of immunosuppressive therapies, whether the intrinsic immunological abnormalities of SLE per se contribute to the susceptibility remains controversial. We report on a patient who presented concurrently with cryptococcal meningitis and cryptococcaemia at the time of her diagnosis of active SLE. This highlights the possibility that intrinsic immunological defects of SLE may be directly responsible for the predisposition to fungal infections. In addition, when SLE patients present with neurological symptoms, the possible presence of central nervous system (CNS) infection must be checked for, even if immunosuppressive treatment is not being considered.
Persistent Identifierhttp://hdl.handle.net/10722/91627
ISSN
2015 Impact Factor: 2.495
2015 SCImago Journal Rankings: 0.953
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorMok, CCen_HK
dc.contributor.authorLau, CSen_HK
dc.contributor.authorYuen, KYen_HK
dc.date.accessioned2010-09-17T10:22:26Z-
dc.date.available2010-09-17T10:22:26Z-
dc.date.issued1998en_HK
dc.identifier.citationClinical And Experimental Rheumatology, 1998, v. 16 n. 2, p. 169-171en_HK
dc.identifier.issn0392-856Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/91627-
dc.description.abstractCryptococcal meningitis is a rare but well recognized complication of systemic lupus erythematosus (SLE). Since in all previously reported cases in the medical literature the patients developed this opportunistic infection as the result of immunosuppressive therapies, whether the intrinsic immunological abnormalities of SLE per se contribute to the susceptibility remains controversial. We report on a patient who presented concurrently with cryptococcal meningitis and cryptococcaemia at the time of her diagnosis of active SLE. This highlights the possibility that intrinsic immunological defects of SLE may be directly responsible for the predisposition to fungal infections. In addition, when SLE patients present with neurological symptoms, the possible presence of central nervous system (CNS) infection must be checked for, even if immunosuppressive treatment is not being considered.en_HK
dc.languageengen_HK
dc.publisherPacini Editore SpA. The Journal's web site is located at http://www.clinexprheumatol.orgen_HK
dc.relation.ispartofClinical and Experimental Rheumatologyen_HK
dc.subjectCryptococcaemiaen_HK
dc.subjectCryptococcal meningitisen_HK
dc.subjectFungal infectionen_HK
dc.subjectLupusen_HK
dc.subject.meshAntifungal Agents - therapeutic useen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshGlucocorticoids - therapeutic useen_HK
dc.subject.meshHumansen_HK
dc.subject.meshLupus Erythematosus, Systemic - complications - drug therapyen_HK
dc.subject.meshMagnetic Resonance Imagingen_HK
dc.subject.meshMeningitis, Cryptococcal - complications - diagnosis - drug therapyen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPrednisolone - therapeutic useen_HK
dc.titleCryptococcal meningitis presenting concurrently with systemic lupus erythematosusen_HK
dc.typeArticleen_HK
dc.identifier.emailLau, CS:cslau@hku.hken_HK
dc.identifier.emailYuen, KY:kyyuen@hkucc.hku.hken_HK
dc.identifier.authorityLau, CS=rp01348en_HK
dc.identifier.authorityYuen, KY=rp00366en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid9536394-
dc.identifier.scopuseid_2-s2.0-0031746434en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0031746434&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume16en_HK
dc.identifier.issue2en_HK
dc.identifier.spage169en_HK
dc.identifier.epage171en_HK
dc.identifier.isiWOS:000072517300010-
dc.publisher.placeItalyen_HK
dc.identifier.scopusauthoridMok, CC=34668219600en_HK
dc.identifier.scopusauthoridLau, CS=14035682100en_HK
dc.identifier.scopusauthoridYuen, KY=36078079100en_HK

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