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Article: Management of systemic lupus erythematosus: A brief update on recent advances

TitleManagement of systemic lupus erythematosus: A brief update on recent advances
Authors
KeywordsAutoimmunity
Connective tissue disorder
Drug treatment
Issue Date2006
PublisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APL
Citation
Aplar Journal Of Rheumatology, 2006, v. 9 n. 4, p. 387-391 How to Cite?
AbstractSystemic lupus erythematosus (SLE) has remained one of the most baffling autoimmune rheumatic diseases since it was described in the 19th century. It is a multisystemic, chronic condition that affects individuals with life-threatening irreversible end-organ damage and debilitating clinical features. The course of SLE varies from periods of quiescence to ones of exacerbation that may involve any organ system in almost any combination. In particular, SLE typically attacks young women at their childbearing years, which makes the therapeutic goals and pharmacological management challenging. The management of patients with SLE in Asia is further complicated by the facts that these patients tend to have a more severe disease, do not have ready access to medical treatment, are not able to afford expensive drugs, especially novel immunosuppressive and biologic agents, and are more susceptible to serious infective complications. In this article, we will provide a brief update on the currently available drug treatment for SLE, and recent advances in this area. The emphases are on early recognition and monitoring of disease complications and the judicious use of immunosuppressive drugs. © 2006 Asia Pacific League of Associations for Rheumatology.
Persistent Identifierhttp://hdl.handle.net/10722/91599
ISSN
References

 

DC FieldValueLanguage
dc.contributor.authorWong, Men_HK
dc.contributor.authorLau, CSen_HK
dc.date.accessioned2010-09-17T10:21:59Z-
dc.date.available2010-09-17T10:21:59Z-
dc.date.issued2006en_HK
dc.identifier.citationAplar Journal Of Rheumatology, 2006, v. 9 n. 4, p. 387-391en_HK
dc.identifier.issn0219-0494en_HK
dc.identifier.urihttp://hdl.handle.net/10722/91599-
dc.description.abstractSystemic lupus erythematosus (SLE) has remained one of the most baffling autoimmune rheumatic diseases since it was described in the 19th century. It is a multisystemic, chronic condition that affects individuals with life-threatening irreversible end-organ damage and debilitating clinical features. The course of SLE varies from periods of quiescence to ones of exacerbation that may involve any organ system in almost any combination. In particular, SLE typically attacks young women at their childbearing years, which makes the therapeutic goals and pharmacological management challenging. The management of patients with SLE in Asia is further complicated by the facts that these patients tend to have a more severe disease, do not have ready access to medical treatment, are not able to afford expensive drugs, especially novel immunosuppressive and biologic agents, and are more susceptible to serious infective complications. In this article, we will provide a brief update on the currently available drug treatment for SLE, and recent advances in this area. The emphases are on early recognition and monitoring of disease complications and the judicious use of immunosuppressive drugs. © 2006 Asia Pacific League of Associations for Rheumatology.en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APLen_HK
dc.relation.ispartofAPLAR Journal of Rheumatologyen_HK
dc.subjectAutoimmunityen_HK
dc.subjectConnective tissue disorderen_HK
dc.subjectDrug treatmenten_HK
dc.titleManagement of systemic lupus erythematosus: A brief update on recent advancesen_HK
dc.typeArticleen_HK
dc.identifier.emailLau, CS:cslau@hku.hken_HK
dc.identifier.authorityLau, CS=rp01348en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1479-8077.2006.00246.xen_HK
dc.identifier.scopuseid_2-s2.0-33751012085en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33751012085&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume9en_HK
dc.identifier.issue4en_HK
dc.identifier.spage387en_HK
dc.identifier.epage391en_HK
dc.identifier.eissn1479-8077-
dc.publisher.placeAustraliaen_HK
dc.identifier.scopusauthoridWong, M=16481455300en_HK
dc.identifier.scopusauthoridLau, CS=14035682100en_HK

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