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Article: Adrenomedullin: Its role in the cardiovascular system

TitleAdrenomedullin: Its role in the cardiovascular system
Authors
KeywordsChemicals And Cas Registry Numbers
Issue Date2004
PublisherThieme Medical Publishers. The Journal's web site is located at http://www.thieme-connect.com/ejournals/toc/svm
Citation
Seminars In Vascular Medicine, 2004, v. 4 n. 2, p. 129-134 How to Cite?
AbstractAdrenomedullin is a 52-amino acid peptide that was first isolated from human pheochromocytoma. Subsequently, it was found to be distributed widely in the body, including throughout the cardiovascular system. It belongs to a family of peptides that include calcitonin gene-related peptide and amylin. Adrenomedullin causes vasorelaxation and influences vascular proliferation and interacts closely with nitric oxide, and it may have a role in the pathophysiology of hypertension, ischemic heart disease, and cardiac and renal failure. Nonpeptide agonists or antagonists of adrenomedullin may have potential therapeutic application. The role of adrenomedullin in septicemic shock also merits further investigation.
Persistent Identifierhttp://hdl.handle.net/10722/91534
ISSN
2008 SCImago Journal Rankings: 0.821
References

 

DC FieldValueLanguage
dc.contributor.authorCheung, BMYen_HK
dc.contributor.authorLi, CYYen_HK
dc.contributor.authorWong, LYFen_HK
dc.date.accessioned2010-09-17T10:20:57Z-
dc.date.available2010-09-17T10:20:57Z-
dc.date.issued2004en_HK
dc.identifier.citationSeminars In Vascular Medicine, 2004, v. 4 n. 2, p. 129-134en_HK
dc.identifier.issn1528-9648en_HK
dc.identifier.urihttp://hdl.handle.net/10722/91534-
dc.description.abstractAdrenomedullin is a 52-amino acid peptide that was first isolated from human pheochromocytoma. Subsequently, it was found to be distributed widely in the body, including throughout the cardiovascular system. It belongs to a family of peptides that include calcitonin gene-related peptide and amylin. Adrenomedullin causes vasorelaxation and influences vascular proliferation and interacts closely with nitric oxide, and it may have a role in the pathophysiology of hypertension, ischemic heart disease, and cardiac and renal failure. Nonpeptide agonists or antagonists of adrenomedullin may have potential therapeutic application. The role of adrenomedullin in septicemic shock also merits further investigation.en_HK
dc.languageengen_HK
dc.publisherThieme Medical Publishers. The Journal's web site is located at http://www.thieme-connect.com/ejournals/toc/svmen_HK
dc.relation.ispartofSeminars in Vascular Medicineen_HK
dc.subjectChemicals And Cas Registry Numbersen_HK
dc.subject.meshAdrenomedullinen_HK
dc.subject.meshAnimalsen_HK
dc.subject.meshCalcitonin Gene-Related Peptide - metabolism - physiologyen_HK
dc.subject.meshCardiovascular Physiological Phenomenaen_HK
dc.subject.meshHumansen_HK
dc.subject.meshPeptides - metabolism - physiologyen_HK
dc.subject.meshReceptors, Calcitonin Gene-Related Peptide - metabolism - physiologyen_HK
dc.subject.meshShock, Septic - physiopathologyen_HK
dc.subject.meshSignal Transduction - physiologyen_HK
dc.subject.meshTissue Distributionen_HK
dc.subject.meshVasodilation - physiologyen_HK
dc.titleAdrenomedullin: Its role in the cardiovascular systemen_HK
dc.typeArticleen_HK
dc.identifier.emailCheung, BMY:mycheung@hku.hken_HK
dc.identifier.authorityCheung, BMY=rp01321en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1055/s-2004-835370en_HK
dc.identifier.pmid15478033-
dc.identifier.scopuseid_2-s2.0-7244250107en_HK
dc.identifier.hkuros101426-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-7244250107&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume4en_HK
dc.identifier.issue2en_HK
dc.identifier.spage129en_HK
dc.identifier.epage134en_HK
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridCheung, BMY=7103294806en_HK
dc.identifier.scopusauthoridLi, CYY=36068172200en_HK
dc.identifier.scopusauthoridWong, LYF=24476809800en_HK

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