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Article: Diastolic blood pressure is related to urinary sodium excretion in hypertensive Chinese patients

TitleDiastolic blood pressure is related to urinary sodium excretion in hypertensive Chinese patients
Authors
KeywordsChemicals And Cas Registry Numbers
Issue Date2000
PublisherOxford University Press. The Journal's web site is located at http://qjmed.oxfordjournals.org/
Citation
Qjm - Monthly Journal Of The Association Of Physicians, 2000, v. 93 n. 3, p. 163-168 How to Cite?
AbstractWe studied 70 Hong Kong Chinese patients with untreated hypertension and 47 normotensive controls. Blood pressure measurements and 24-h urine collection were performed for each patient, and were repeated 12 weeks later in 14 hypertensive patients who remained untreated. Twenty-two hypertensive patients underwent ambulatory blood pressure monitoring. The primary hypothesis tested was a correlation between diastolic blood pressure and 24-h urinary sodium excretion. In the hypertensive patients, diastolic blood pressure correlated with 24-h urinary sodium excretion (r = 0.41, p < 0.001), even after adjustment for age, gender, body mass index, ethanol intake and season (r = 0.34, p = 0.02). In normotensive controls, diastolic blood pressure did not correlate with sodium excretion (r = 0.21, p = 0.16). A correlation between diastolic blood pressure and sodium excretion was also observed in the patients who underwent ambulatory blood pressure monitoring (r = 0.47, p = 0.026), and in repeat measurements in untreated patients (r = 0.60, p = 0.02). Systolic blood pressure did not correlate with sodium excretion, although it increased with patient age (0.6 ± 0.1 mmHg/year, p < 0.001). In a multiple regression analysis with diastolic blood pressure as the dependent variable, the regression coefficient was 0.06 ± 0.02 mmHg/mmol Na. The regression coefficients for ambulatory diastolic blood pressure and diastolic pressure repeated at 12 weeks were 0.07 ± 0.03 and 0.09 ± 0.04 mmHg/mmol Na, respectively. Urinary sodium excretion was related to diastolic blood pressure in our hypertensive patients, accounting for 17% of the variance of diastolic blood pressure.
Persistent Identifierhttp://hdl.handle.net/10722/91449
ISSN
2015 Impact Factor: 2.824
2015 SCImago Journal Rankings: 0.633
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCheung, BMYen_HK
dc.contributor.authorHo, SPCen_HK
dc.contributor.authorCheung, AHKen_HK
dc.contributor.authorLau, CPen_HK
dc.date.accessioned2010-09-17T10:19:35Z-
dc.date.available2010-09-17T10:19:35Z-
dc.date.issued2000en_HK
dc.identifier.citationQjm - Monthly Journal Of The Association Of Physicians, 2000, v. 93 n. 3, p. 163-168en_HK
dc.identifier.issn1460-2725en_HK
dc.identifier.urihttp://hdl.handle.net/10722/91449-
dc.description.abstractWe studied 70 Hong Kong Chinese patients with untreated hypertension and 47 normotensive controls. Blood pressure measurements and 24-h urine collection were performed for each patient, and were repeated 12 weeks later in 14 hypertensive patients who remained untreated. Twenty-two hypertensive patients underwent ambulatory blood pressure monitoring. The primary hypothesis tested was a correlation between diastolic blood pressure and 24-h urinary sodium excretion. In the hypertensive patients, diastolic blood pressure correlated with 24-h urinary sodium excretion (r = 0.41, p < 0.001), even after adjustment for age, gender, body mass index, ethanol intake and season (r = 0.34, p = 0.02). In normotensive controls, diastolic blood pressure did not correlate with sodium excretion (r = 0.21, p = 0.16). A correlation between diastolic blood pressure and sodium excretion was also observed in the patients who underwent ambulatory blood pressure monitoring (r = 0.47, p = 0.026), and in repeat measurements in untreated patients (r = 0.60, p = 0.02). Systolic blood pressure did not correlate with sodium excretion, although it increased with patient age (0.6 ± 0.1 mmHg/year, p < 0.001). In a multiple regression analysis with diastolic blood pressure as the dependent variable, the regression coefficient was 0.06 ± 0.02 mmHg/mmol Na. The regression coefficients for ambulatory diastolic blood pressure and diastolic pressure repeated at 12 weeks were 0.07 ± 0.03 and 0.09 ± 0.04 mmHg/mmol Na, respectively. Urinary sodium excretion was related to diastolic blood pressure in our hypertensive patients, accounting for 17% of the variance of diastolic blood pressure.en_HK
dc.languageengen_HK
dc.publisherOxford University Press. The Journal's web site is located at http://qjmed.oxfordjournals.org/en_HK
dc.relation.ispartofQJM - Monthly Journal of the Association of Physiciansen_HK
dc.subjectChemicals And Cas Registry Numbersen_HK
dc.subject.meshAdolescenten_HK
dc.subject.meshAdulten_HK
dc.subject.meshAge Factorsen_HK
dc.subject.meshAgeden_HK
dc.subject.meshAlcohol Drinkingen_HK
dc.subject.meshBlood Pressure - physiologyen_HK
dc.subject.meshBody Mass Indexen_HK
dc.subject.meshCase-Control Studiesen_HK
dc.subject.meshChina - ethnologyen_HK
dc.subject.meshCreatinine - urineen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHong Kongen_HK
dc.subject.meshHumansen_HK
dc.subject.meshHypertension - ethnology - metabolism - physiopathologyen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPotassium - urineen_HK
dc.subject.meshProspective Studiesen_HK
dc.subject.meshRegression Analysisen_HK
dc.subject.meshSex Factorsen_HK
dc.subject.meshSodium - urineen_HK
dc.subject.meshSodium Chloride, Dietary - adverse effectsen_HK
dc.titleDiastolic blood pressure is related to urinary sodium excretion in hypertensive Chinese patientsen_HK
dc.typeArticleen_HK
dc.identifier.emailCheung, BMY:mycheung@hku.hken_HK
dc.identifier.authorityCheung, BMY=rp01321en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid10751235-
dc.identifier.scopuseid_2-s2.0-0034051149en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034051149&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume93en_HK
dc.identifier.issue3en_HK
dc.identifier.spage163en_HK
dc.identifier.epage168en_HK
dc.identifier.isiWOS:000085753400005-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridCheung, BMY=7103294806en_HK
dc.identifier.scopusauthoridHo, SPC=12794365900en_HK
dc.identifier.scopusauthoridCheung, AHK=12795914100en_HK
dc.identifier.scopusauthoridLau, CP=7401968501en_HK

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