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Article: Single-nucleotide polymorphisms near the microsatellite D17S1303 and the development of hypertension in a 6-year longitudinal study

TitleSingle-nucleotide polymorphisms near the microsatellite D17S1303 and the development of hypertension in a 6-year longitudinal study
Authors
Issue Date2008
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/jhh
Citation
Journal Of Human Hypertension, 2008, v. 22 n. 2, p. 151-153 How to Cite?
AbstractThis study examined the association of tagging single-nucleotide polymorphisms (SNPs) in the 130 kb region surrounding the microsatellite D17S1303 on chromosome 17p12 with the development of hypertension after 6 years in a cohort of 232 Hong Kong Chinese adults. Four SNPs (rs9899362, rs10491093, rs11658572 and rs9913883) were associated with the development of hypertension (P<0.05), but these associations require confirmation in future studies. Nevertheless, our study provides further evidence for the presence of an unidentified gene or a regulatory element predisposing to hypertension in a region approximately 24 kb downstream of D17S1303.
Persistent Identifierhttp://hdl.handle.net/10722/91429
ISSN
2014 Impact Factor: 2.700
2014 SCImago Journal Rankings: 0.833
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCheung, BMYen_HK
dc.contributor.authorOng, KLen_HK
dc.contributor.authorLeung, RYHen_HK
dc.contributor.authorWong, LYFen_HK
dc.contributor.authorSong, YQen_HK
dc.contributor.authorSham, PCen_HK
dc.date.accessioned2010-09-17T10:19:15Z-
dc.date.available2010-09-17T10:19:15Z-
dc.date.issued2008en_HK
dc.identifier.citationJournal Of Human Hypertension, 2008, v. 22 n. 2, p. 151-153en_HK
dc.identifier.issn0950-9240en_HK
dc.identifier.urihttp://hdl.handle.net/10722/91429-
dc.description.abstractThis study examined the association of tagging single-nucleotide polymorphisms (SNPs) in the 130 kb region surrounding the microsatellite D17S1303 on chromosome 17p12 with the development of hypertension after 6 years in a cohort of 232 Hong Kong Chinese adults. Four SNPs (rs9899362, rs10491093, rs11658572 and rs9913883) were associated with the development of hypertension (P<0.05), but these associations require confirmation in future studies. Nevertheless, our study provides further evidence for the presence of an unidentified gene or a regulatory element predisposing to hypertension in a region approximately 24 kb downstream of D17S1303.-
dc.languageengen_HK
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/jhhen_HK
dc.relation.ispartofJournal of Human Hypertensionen_HK
dc.subject.meshAdult-
dc.subject.meshChromosomes, Human, 16-18-
dc.subject.meshHypertension - genetics-
dc.subject.meshMicrosatellite Repeats-
dc.subject.meshPolymorphism, Single Nucleotide - genetics-
dc.titleSingle-nucleotide polymorphisms near the microsatellite D17S1303 and the development of hypertension in a 6-year longitudinal studyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0950-9240&volume=22&spage=151&epage=153&date=2008&atitle=Single-nucleotide+polymorphisms+near+the+microsatellite+D17S1303+and+the+development+of+hypertension+in+a+6-year+longitudinal+study-
dc.identifier.emailCheung, BMY: mycheung@hku.hken_HK
dc.identifier.emailSong, YQ: songy@hku.hken_HK
dc.identifier.emailSham, PC: pcsham@hku.hken_HK
dc.identifier.authorityCheung, BMY=rp01321en_HK
dc.identifier.authoritySong, YQ=rp00488en_HK
dc.identifier.authoritySham, PC=rp00459en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1038/sj.jhh.1002283en_HK
dc.identifier.pmid17728798en_HK
dc.identifier.scopuseid_2-s2.0-38349132312en_HK
dc.identifier.hkuros139062-
dc.identifier.hkuros158268en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-38349132312&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume22en_HK
dc.identifier.issue2en_HK
dc.identifier.spage151en_HK
dc.identifier.epage153en_HK
dc.identifier.isiWOS:000252426400018-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridCheung, BMY=7103294806en_HK
dc.identifier.scopusauthoridOng, KL=8340854000en_HK
dc.identifier.scopusauthoridLeung, RYH=7101876102en_HK
dc.identifier.scopusauthoridWong, LYF=36947365900en_HK
dc.identifier.scopusauthoridSong, YQ=7404921212en_HK
dc.identifier.scopusauthoridSham, PC=34573429300en_HK
dc.identifier.citeulike1608083-

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