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Article: Single-nucleotide polymorphisms near the microsatellite D17S1303 and the development of hypertension in a 6-year longitudinal study
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TitleSingle-nucleotide polymorphisms near the microsatellite D17S1303 and the development of hypertension in a 6-year longitudinal study
 
AuthorsCheung, BMY1
Ong, KL1
Leung, RYH1
Wong, LYF1
Song, YQ1
Sham, PC1
 
Issue Date2008
 
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/jhh
 
CitationJournal Of Human Hypertension, 2008, v. 22 n. 2, p. 151-153 [How to Cite?]
DOI: http://dx.doi.org/10.1038/sj.jhh.1002283
 
AbstractThis study examined the association of tagging single-nucleotide polymorphisms (SNPs) in the 130 kb region surrounding the microsatellite D17S1303 on chromosome 17p12 with the development of hypertension after 6 years in a cohort of 232 Hong Kong Chinese adults. Four SNPs (rs9899362, rs10491093, rs11658572 and rs9913883) were associated with the development of hypertension (P<0.05), but these associations require confirmation in future studies. Nevertheless, our study provides further evidence for the presence of an unidentified gene or a regulatory element predisposing to hypertension in a region approximately 24 kb downstream of D17S1303.
 
ISSN0950-9240
2013 Impact Factor: 2.692
2013 SCImago Journal Rankings: 1.177
 
DOIhttp://dx.doi.org/10.1038/sj.jhh.1002283
 
ISI Accession Number IDWOS:000252426400018
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorCheung, BMY
 
dc.contributor.authorOng, KL
 
dc.contributor.authorLeung, RYH
 
dc.contributor.authorWong, LYF
 
dc.contributor.authorSong, YQ
 
dc.contributor.authorSham, PC
 
dc.date.accessioned2010-09-17T10:19:15Z
 
dc.date.available2010-09-17T10:19:15Z
 
dc.date.issued2008
 
dc.description.abstractThis study examined the association of tagging single-nucleotide polymorphisms (SNPs) in the 130 kb region surrounding the microsatellite D17S1303 on chromosome 17p12 with the development of hypertension after 6 years in a cohort of 232 Hong Kong Chinese adults. Four SNPs (rs9899362, rs10491093, rs11658572 and rs9913883) were associated with the development of hypertension (P<0.05), but these associations require confirmation in future studies. Nevertheless, our study provides further evidence for the presence of an unidentified gene or a regulatory element predisposing to hypertension in a region approximately 24 kb downstream of D17S1303.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationJournal Of Human Hypertension, 2008, v. 22 n. 2, p. 151-153 [How to Cite?]
DOI: http://dx.doi.org/10.1038/sj.jhh.1002283
 
dc.identifier.citeulike1608083
 
dc.identifier.doihttp://dx.doi.org/10.1038/sj.jhh.1002283
 
dc.identifier.epage153
 
dc.identifier.hkuros139062
 
dc.identifier.hkuros158268
 
dc.identifier.isiWOS:000252426400018
 
dc.identifier.issn0950-9240
2013 Impact Factor: 2.692
2013 SCImago Journal Rankings: 1.177
 
dc.identifier.issue2
 
dc.identifier.openurl
 
dc.identifier.pmid17728798
 
dc.identifier.scopuseid_2-s2.0-38349132312
 
dc.identifier.spage151
 
dc.identifier.urihttp://hdl.handle.net/10722/91429
 
dc.identifier.volume22
 
dc.languageeng
 
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/jhh
 
dc.publisher.placeUnited Kingdom
 
dc.relation.ispartofJournal of Human Hypertension
 
dc.relation.referencesReferences in Scopus
 
dc.subject.meshAdult
 
dc.subject.meshChromosomes, Human, 16-18
 
dc.subject.meshHypertension - genetics
 
dc.subject.meshMicrosatellite Repeats
 
dc.subject.meshPolymorphism, Single Nucleotide - genetics
 
dc.titleSingle-nucleotide polymorphisms near the microsatellite D17S1303 and the development of hypertension in a 6-year longitudinal study
 
dc.typeArticle
 
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Author Affiliations
  1. The University of Hong Kong