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Article: Performance of serial time-encoded amplified microscope

TitlePerformance of serial time-encoded amplified microscope
Authors
Issue Date2010
PublisherOptical Society of America. The Journal's web site is located at http://www.opticsexpress.org
Citation
Optics Express, 2010, v. 18 n. 10, p. 10016-10028 How to Cite?
AbstractSerial time-encoded amplified microscopy (STEAM) is an entirely new imaging modality that enables ultrafast continuous real-time imaging with high sensitivity. By means of optical image amplification, STEAM overcomes the fundamental tradeoff between sensitivity and speed that affects virtually all optical imaging systems. Unlike the conventional microscope systems, the performance of STEAM depends not only on the lenses, but also on the properties of other components that are unique to STEAM, namely the spatial disperser, the group velocity dispersion element, and the back-end electronic digitizer. In this paper, we present an analysis that shows how these considerations affect the spatial resolution, and how they create a trade-off between the number of pixels and the frame rate of the STEAM imager. We also quantify how STEAM's optical image amplification feature improves the imaging sensitivity. These analyses not only provide valuable insight into the operation of STEAM technology but also serve as a blue print for implementation and optimization of this new imaging technology. ©2010 Optical Society of America.
Persistent Identifierhttp://hdl.handle.net/10722/91333
ISSN
2015 Impact Factor: 3.148
2015 SCImago Journal Rankings: 2.186
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTsia, KKen_HK
dc.contributor.authorGoda, Ken_HK
dc.contributor.authorCapewell, Den_HK
dc.contributor.authorJalali, Ben_HK
dc.date.accessioned2010-09-17T10:17:12Z-
dc.date.available2010-09-17T10:17:12Z-
dc.date.issued2010en_HK
dc.identifier.citationOptics Express, 2010, v. 18 n. 10, p. 10016-10028en_HK
dc.identifier.issn1094-4087en_HK
dc.identifier.urihttp://hdl.handle.net/10722/91333-
dc.description.abstractSerial time-encoded amplified microscopy (STEAM) is an entirely new imaging modality that enables ultrafast continuous real-time imaging with high sensitivity. By means of optical image amplification, STEAM overcomes the fundamental tradeoff between sensitivity and speed that affects virtually all optical imaging systems. Unlike the conventional microscope systems, the performance of STEAM depends not only on the lenses, but also on the properties of other components that are unique to STEAM, namely the spatial disperser, the group velocity dispersion element, and the back-end electronic digitizer. In this paper, we present an analysis that shows how these considerations affect the spatial resolution, and how they create a trade-off between the number of pixels and the frame rate of the STEAM imager. We also quantify how STEAM's optical image amplification feature improves the imaging sensitivity. These analyses not only provide valuable insight into the operation of STEAM technology but also serve as a blue print for implementation and optimization of this new imaging technology. ©2010 Optical Society of America.en_HK
dc.languageengen_HK
dc.publisherOptical Society of America. The Journal's web site is located at http://www.opticsexpress.orgen_HK
dc.relation.ispartofOptics Expressen_HK
dc.rightsOptics Express. Copyright © Optical Society of America.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsThis paper was published in Optics Express and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/abstract.cfm?URI=oe-18-10-10016. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.-
dc.subject.meshAmplifiers, Electronic-
dc.subject.meshImage Enhancement - instrumentation-
dc.subject.meshLenses-
dc.subject.meshMicroscopy - instrumentation-
dc.subject.meshSignal Processing, Computer-Assisted - instrumentation-
dc.titlePerformance of serial time-encoded amplified microscopeen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1094-4087&volume=18&issue=10&spage=10016&epage=10028&date=2010&atitle=Performance+of+serial+time-encoded+amplified+microscope-
dc.identifier.emailTsia, KK:tsia@hku.hken_HK
dc.identifier.authorityTsia, KK=rp01389en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1364/OE.18.010016en_HK
dc.identifier.pmid20588855-
dc.identifier.scopuseid_2-s2.0-77952747342en_HK
dc.identifier.hkuros176032-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77952747342&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume18en_HK
dc.identifier.issue10en_HK
dc.identifier.spage10016en_HK
dc.identifier.epage10028en_HK
dc.identifier.isiWOS:000277560000027-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridTsia, KK=6506659574en_HK
dc.identifier.scopusauthoridGoda, K=35227304100en_HK
dc.identifier.scopusauthoridCapewell, D=6603243853en_HK
dc.identifier.scopusauthoridJalali, B=7004889917en_HK

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