File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Kinetic studies of imidazole and its methyl derivative binding to metmyoglobin: Effects of substitute methyl on the binding affinity

TitleKinetic studies of imidazole and its methyl derivative binding to metmyoglobin: Effects of substitute methyl on the binding affinity
Authors
Qian, CYao, YWu, YTang, W
KeywordsChemicals And Cas Registry Numbers
Issue Date2000
PublisherSpringer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0966-0844
Citation
Biometals, 2000, v. 13 n. 3, p. 267-272 How to Cite?
DOI: http://dx.doi.org/10.1023/A:1009274731507
AbstractThe binding of imidazole and imidazole derivatives (4- and 2-MeIm) to the metMb was studied by 1H NMR spectroscopy to elucidate the effects of different methyl substitution positions on the affinity and kinetics of binding to metMb. These exogenous ligands can form stable complexes with metMb except 2-MeIm. Kinetics and equilibrium data for the binding of imidazole and 4-MeIm to metMb have been obtained by 2D EXSY, and the reasons for the different affinity are also discussed.
Persistent Identifierhttp://hdl.handle.net/10722/91174
ISSN
0966-0844
2023 Impact Factor: 4.1
2023 SCImago Journal Rankings: 0.618
ISI Accession Number ID
WOS:000165088300010
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorQian, Cen_HK
dc.contributor.authorYao, Yen_HK
dc.contributor.authorWu, Yen_HK
dc.contributor.authorTang, Wen_HK
dc.date.accessioned2010-09-17T10:14:12Z-
dc.date.available2010-09-17T10:14:12Z-
dc.date.issued2000en_HK
dc.identifier.citationBiometals, 2000, v. 13 n. 3, p. 267-272en_HK
dc.identifier.issn0966-0844en_HK
dc.identifier.urihttp://hdl.handle.net/10722/91174-
dc.description.abstractThe binding of imidazole and imidazole derivatives (4- and 2-MeIm) to the metMb was studied by 1H NMR spectroscopy to elucidate the effects of different methyl substitution positions on the affinity and kinetics of binding to metMb. These exogenous ligands can form stable complexes with metMb except 2-MeIm. Kinetics and equilibrium data for the binding of imidazole and 4-MeIm to metMb have been obtained by 2D EXSY, and the reasons for the different affinity are also discussed.en_HK
dc.languageengen_HK
dc.publisherSpringer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0966-0844en_HK
dc.relation.ispartofBioMetalsen_HK
dc.subjectChemicals And Cas Registry Numbersen_HK
dc.subject.meshAnimalsen_HK
dc.subject.meshHorsesen_HK
dc.subject.meshImidazoles - chemistryen_HK
dc.subject.meshKineticsen_HK
dc.subject.meshLigandsen_HK
dc.subject.meshMetmyoglobin - chemistryen_HK
dc.subject.meshMuscle, Skeletal - chemistry - metabolismen_HK
dc.subject.meshNuclear Magnetic Resonance, Biomolecularen_HK
dc.subject.meshProtein Bindingen_HK
dc.titleKinetic studies of imidazole and its methyl derivative binding to metmyoglobin: Effects of substitute methyl on the binding affinityen_HK
dc.typeArticleen_HK
dc.identifier.emailQian, C:cmqian@hku.hken_HK
dc.identifier.authorityQian, C=rp01371en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1023/A:1009274731507en_HK
dc.identifier.pmid11127899-
dc.identifier.scopuseid_2-s2.0-0033695125en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0033695125&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume13en_HK
dc.identifier.issue3en_HK
dc.identifier.spage267en_HK
dc.identifier.epage272en_HK
dc.identifier.isiWOS:000165088300010-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridQian, C=7202311105en_HK
dc.identifier.scopusauthoridYao, Y=55202633100en_HK
dc.identifier.scopusauthoridWu, Y=7406899424en_HK
dc.identifier.scopusauthoridTang, W=7403430524en_HK
dc.identifier.issnl0966-0844-

Export via OAI-PMH Interface in XML Formats

OR

Export to Other Non-XML Formats