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Article: Potent anti-microbial activity of traditional Chinese medicine herbs against Candida species

TitlePotent anti-microbial activity of traditional Chinese medicine herbs against Candida species
Authors
KeywordsSpecies Index: Candida
Candida Albicans
Candida Dubliniensis
Candida Glabrata
Candida Tropicalis
Issatchenkia Orientalis
Issue Date2008
PublisherWiley-Blackwell Verlag GmbH. The Journal's web site is located at http://www.blackwellpublishing.com/journals/MYC
Citation
Mycoses, 2008, v. 51 n. 1, p. 30-34 How to Cite?
AbstractAnti-candidial activities of eight traditional Chinese medicinal (TCM) herbs were evaluated against six different Candida species. TCM preparations were screened for antifungal activity using a standard agar diffusion assay. Following identification of potential candidate herbs, their minimum inhibitory concentration (MIC) values were determined using the standardised NCCLS M-27A broth microdilution assay. Among TCM herbs, Rhizoma Coptidis had potent antifungal activity against Candida glabrata, Candida krusei and Candida tropicalis, but not against Candida albicans, Candida dubliniensis and Candida parapsolosis. The MIC values of the Rhizoma Coptidis against C. glabrata, C. krusei and C. tropicalis were 50, 50 and 100 μg ml-1 respectively. We report here, for the first time, the potent antifungal activity of Rhizoma Coptidis and Cortex phellodendri Chinesis on three different non-albicans Candida species, C. glabrata, C. krusei and C. tropicalis and hence their possible use as therapeutic agents. © 2007 The Authors.
Persistent Identifierhttp://hdl.handle.net/10722/90696
ISSN
2015 Impact Factor: 2.332
2015 SCImago Journal Rankings: 0.921
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorSeneviratne, CJen_HK
dc.contributor.authorWong, RWKen_HK
dc.contributor.authorSamaranayake, LPen_HK
dc.date.accessioned2010-09-17T10:06:56Z-
dc.date.available2010-09-17T10:06:56Z-
dc.date.issued2008en_HK
dc.identifier.citationMycoses, 2008, v. 51 n. 1, p. 30-34en_HK
dc.identifier.issn0933-7407en_HK
dc.identifier.urihttp://hdl.handle.net/10722/90696-
dc.description.abstractAnti-candidial activities of eight traditional Chinese medicinal (TCM) herbs were evaluated against six different Candida species. TCM preparations were screened for antifungal activity using a standard agar diffusion assay. Following identification of potential candidate herbs, their minimum inhibitory concentration (MIC) values were determined using the standardised NCCLS M-27A broth microdilution assay. Among TCM herbs, Rhizoma Coptidis had potent antifungal activity against Candida glabrata, Candida krusei and Candida tropicalis, but not against Candida albicans, Candida dubliniensis and Candida parapsolosis. The MIC values of the Rhizoma Coptidis against C. glabrata, C. krusei and C. tropicalis were 50, 50 and 100 μg ml-1 respectively. We report here, for the first time, the potent antifungal activity of Rhizoma Coptidis and Cortex phellodendri Chinesis on three different non-albicans Candida species, C. glabrata, C. krusei and C. tropicalis and hence their possible use as therapeutic agents. © 2007 The Authors.en_HK
dc.languageengen_HK
dc.publisherWiley-Blackwell Verlag GmbH. The Journal's web site is located at http://www.blackwellpublishing.com/journals/MYCen_HK
dc.relation.ispartofMycosesen_HK
dc.subjectSpecies Index: Candidaen_HK
dc.subjectCandida Albicansen_HK
dc.subjectCandida Dubliniensisen_HK
dc.subjectCandida Glabrataen_HK
dc.subjectCandida Tropicalisen_HK
dc.subjectIssatchenkia Orientalisen_HK
dc.subject.meshAntifungal Agents - pharmacologyen_HK
dc.subject.meshCandida - drug effectsen_HK
dc.subject.meshDrugs, Chinese Herbal - pharmacologyen_HK
dc.subject.meshMicrobial Sensitivity Testsen_HK
dc.titlePotent anti-microbial activity of traditional Chinese medicine herbs against Candida speciesen_HK
dc.typeArticleen_HK
dc.identifier.emailSeneviratne, CJ:jaya@hku.hken_HK
dc.identifier.emailWong, RWK:fyoung@hkucc.hku.hken_HK
dc.identifier.emailSamaranayake, LP:lakshman@hku.hken_HK
dc.identifier.authoritySeneviratne, CJ=rp01372en_HK
dc.identifier.authorityWong, RWK=rp00038en_HK
dc.identifier.authoritySamaranayake, LP=rp00023en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1439-0507.2007.01431.xen_HK
dc.identifier.pmid18076592-
dc.identifier.scopuseid_2-s2.0-36749016813en_HK
dc.identifier.hkuros139794-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-36749016813&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume51en_HK
dc.identifier.issue1en_HK
dc.identifier.spage30en_HK
dc.identifier.epage34en_HK
dc.identifier.eissn1439-0507-
dc.identifier.isiWOS:000251386800005-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridSeneviratne, CJ=6701897753en_HK
dc.identifier.scopusauthoridWong, RWK=7402127170en_HK
dc.identifier.scopusauthoridSamaranayake, LP=7102761002en_HK
dc.identifier.citeulike2069704-

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