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Article: Incorporation of casein phosphopeptide-amorphous calcium phosphate into a glass-ionomer cement

TitleIncorporation of casein phosphopeptide-amorphous calcium phosphate into a glass-ionomer cement
Authors
KeywordsChemicals And Cas Registry Numbers
Issue Date2003
PublisherSage Publications, Inc.. The Journal's web site is located at http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201925
Citation
Journal Of Dental Research, 2003, v. 82 n. 11, p. 914-918 How to Cite?
AbstractCasein phosphopeptide-amorphous calcium phosphate (CPP-ACP) nanocomplexes have been shown to prevent demineralization and promote remineralization of enamel subsurface lesions in animal and in situ caries models. The aim of this study was to determine the effect of incorporating CPP-ACP into a self-cured glass-ionomer cement (GIC). Incorporation of 1.56% w/w CPP-ACP into the GIC significantly increased microtensile bond strength (33%) and compressive strength (23%) and significantly enhanced the release of calcium, phosphate, and fluoride ions at neutral and acidic pH. MALDI mass spectrometry also showed casein phosphopeptides from the CPP-ACP nanocomplexes to be released. The release of CPP-ACP and fluoride from the CPP-ACP-containing GIC was associated with enhanced protection of the adjacent dentin during acid challenge in vitro.
Persistent Identifierhttp://hdl.handle.net/10722/90666
ISSN
2015 Impact Factor: 4.602
2015 SCImago Journal Rankings: 1.714
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorMazzaoui, SAen_HK
dc.contributor.authorBurrow, MFen_HK
dc.contributor.authorTyas, MJen_HK
dc.contributor.authorDashper, SGen_HK
dc.contributor.authorEakins, Den_HK
dc.contributor.authorReynolds, ECen_HK
dc.date.accessioned2010-09-17T10:06:29Z-
dc.date.available2010-09-17T10:06:29Z-
dc.date.issued2003en_HK
dc.identifier.citationJournal Of Dental Research, 2003, v. 82 n. 11, p. 914-918en_HK
dc.identifier.issn0022-0345en_HK
dc.identifier.urihttp://hdl.handle.net/10722/90666-
dc.description.abstractCasein phosphopeptide-amorphous calcium phosphate (CPP-ACP) nanocomplexes have been shown to prevent demineralization and promote remineralization of enamel subsurface lesions in animal and in situ caries models. The aim of this study was to determine the effect of incorporating CPP-ACP into a self-cured glass-ionomer cement (GIC). Incorporation of 1.56% w/w CPP-ACP into the GIC significantly increased microtensile bond strength (33%) and compressive strength (23%) and significantly enhanced the release of calcium, phosphate, and fluoride ions at neutral and acidic pH. MALDI mass spectrometry also showed casein phosphopeptides from the CPP-ACP nanocomplexes to be released. The release of CPP-ACP and fluoride from the CPP-ACP-containing GIC was associated with enhanced protection of the adjacent dentin during acid challenge in vitro.en_HK
dc.languageengen_HK
dc.publisherSage Publications, Inc.. The Journal's web site is located at http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201925en_HK
dc.relation.ispartofJournal of Dental Researchen_HK
dc.subjectChemicals And Cas Registry Numbersen_HK
dc.subject.meshAnalysis of Varianceen_HK
dc.subject.meshCalcium - analysisen_HK
dc.subject.meshCariostatic Agents - analysisen_HK
dc.subject.meshCaseinsen_HK
dc.subject.meshCompressive Strengthen_HK
dc.subject.meshDental Bondingen_HK
dc.subject.meshDental Stress Analysisen_HK
dc.subject.meshDentinen_HK
dc.subject.meshFluorides - analysisen_HK
dc.subject.meshGlass Ionomer Cements - chemistry - therapeutic useen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaterials Testingen_HK
dc.subject.meshMolaren_HK
dc.subject.meshPhosphates - analysisen_HK
dc.subject.meshSpectrometry, Mass, Matrix-Assisted Laser Desorption-Ionizationen_HK
dc.subject.meshTensile Strengthen_HK
dc.subject.meshTooth Demineralization - prevention & controlen_HK
dc.titleIncorporation of casein phosphopeptide-amorphous calcium phosphate into a glass-ionomer cementen_HK
dc.typeArticleen_HK
dc.identifier.emailBurrow, MF:mfburr58@hku.hken_HK
dc.identifier.authorityBurrow, MF=rp01306en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid14578505-
dc.identifier.scopuseid_2-s2.0-0642374094en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0642374094&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume82en_HK
dc.identifier.issue11en_HK
dc.identifier.spage914en_HK
dc.identifier.epage918en_HK
dc.identifier.isiWOS:000186185400014-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridMazzaoui, SA=6602848678en_HK
dc.identifier.scopusauthoridBurrow, MF=7005876730en_HK
dc.identifier.scopusauthoridTyas, MJ=7006088443en_HK
dc.identifier.scopusauthoridDashper, SG=6603692498en_HK
dc.identifier.scopusauthoridEakins, D=9745724700en_HK
dc.identifier.scopusauthoridReynolds, EC=35550178300en_HK

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