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Article: The concept of heavy tamponades - Chances and limitations

TitleThe concept of heavy tamponades - Chances and limitations
Authors
KeywordsIntraocular tamponade agents
PFCL
Retina
Issue Date2008
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00417/index.htm
Citation
Graefe's Archive For Clinical And Experimental Ophthalmology, 2008, v. 246 n. 9, p. 1217-1224 How to Cite?
AbstractBackground: Proliferative vitreoretinopathy in the inferior retina remains clinically challenging. Heavier than water intraocular tamponades have been developed to improve inferior tamponading properties. In addition to inferior PVR, there seem to be other applications such as persistent macular holes or PVR in trauma eyes. Materials and methods: Review of the literature on clinical application of heavy tamponades. The review also discusses the theoretical background of heavy tamponades and possible future developments. Results: The parameters of an optimal intraocular tamponade are defined, and the influences of the specific gravity, buoyancy, interfacial tension, and viscosity are discussed. Perfluorocarbon liquids and partially fluorinated alkanes were associated with tamponade emulsification, intraocular inflammation, and rise in intraocular pressure that was less prominent in admixtures of these substances with silicone oil (heavy silicone oils). Two recently developed heavy silicone oil tamponades, Oxane HD and Densiron 68, are well-tolerated and have entered clinical practice. The side effects are associated with the chemical properties of the tamponading agent, and seem comparable to the ones seen with conventional silicone oil. Conclusion: Heavy silicone oil tamponade improves inferior tamponade, and may be considered a new generation of intraocular tamponades. © Springer-Verlag 2008.
Persistent Identifierhttp://hdl.handle.net/10722/90374
ISSN
2015 Impact Factor: 1.991
2015 SCImago Journal Rankings: 1.217
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorJoussen, AMen_HK
dc.contributor.authorWong, Den_HK
dc.date.accessioned2010-09-06T10:09:29Z-
dc.date.available2010-09-06T10:09:29Z-
dc.date.issued2008en_HK
dc.identifier.citationGraefe's Archive For Clinical And Experimental Ophthalmology, 2008, v. 246 n. 9, p. 1217-1224en_HK
dc.identifier.issn0721-832Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/90374-
dc.description.abstractBackground: Proliferative vitreoretinopathy in the inferior retina remains clinically challenging. Heavier than water intraocular tamponades have been developed to improve inferior tamponading properties. In addition to inferior PVR, there seem to be other applications such as persistent macular holes or PVR in trauma eyes. Materials and methods: Review of the literature on clinical application of heavy tamponades. The review also discusses the theoretical background of heavy tamponades and possible future developments. Results: The parameters of an optimal intraocular tamponade are defined, and the influences of the specific gravity, buoyancy, interfacial tension, and viscosity are discussed. Perfluorocarbon liquids and partially fluorinated alkanes were associated with tamponade emulsification, intraocular inflammation, and rise in intraocular pressure that was less prominent in admixtures of these substances with silicone oil (heavy silicone oils). Two recently developed heavy silicone oil tamponades, Oxane HD and Densiron 68, are well-tolerated and have entered clinical practice. The side effects are associated with the chemical properties of the tamponading agent, and seem comparable to the ones seen with conventional silicone oil. Conclusion: Heavy silicone oil tamponade improves inferior tamponade, and may be considered a new generation of intraocular tamponades. © Springer-Verlag 2008.en_HK
dc.languageengen_HK
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00417/index.htmen_HK
dc.relation.ispartofGraefe's Archive for Clinical and Experimental Ophthalmologyen_HK
dc.rightsThe original publication is available at www.springerlink.com-
dc.subjectIntraocular tamponade agentsen_HK
dc.subjectPFCLen_HK
dc.subjectRetinaen_HK
dc.subject.meshFluorocarbons - chemistry - therapeutic use-
dc.subject.meshRetinal Diseases - therapy-
dc.subject.meshSilicone Oils - chemistry - therapeutic use-
dc.subject.meshSpecific Gravity-
dc.subject.meshSurface Tension-
dc.titleThe concept of heavy tamponades - Chances and limitationsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0721-832X&volume=246&issue=9&spage=1217&epage=1224&date=2008&atitle=The+concept+of+heavy+tamponades-chances+and+limitationsen_HK
dc.identifier.emailWong, D: shdwong@hku.hken_HK
dc.identifier.authorityWong, D=rp00516en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00417-008-0861-0en_HK
dc.identifier.pmid18546009-
dc.identifier.scopuseid_2-s2.0-48449083201en_HK
dc.identifier.hkuros152779en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-48449083201&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume246en_HK
dc.identifier.issue9en_HK
dc.identifier.spage1217en_HK
dc.identifier.epage1224en_HK
dc.identifier.isiWOS:000257932500001-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridJoussen, AM=35080476300en_HK
dc.identifier.scopusauthoridWong, D=7401536078en_HK

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