File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Simultaneous spectral domain OCT and fundus autofluorescence imaging of the macula and microperimetric correspondence after successful repair of rhegmatogenous retinal detachment

TitleSimultaneous spectral domain OCT and fundus autofluorescence imaging of the macula and microperimetric correspondence after successful repair of rhegmatogenous retinal detachment
Authors
Issue Date2010
PublisherBMJ Publishing Group. The Journal's web site is located at http://bjo.bmjjournals.com/
Citation
British Journal Of Ophthalmology, 2010, v. 94 n. 3, p. 311-318 How to Cite?
AbstractBackground/aims: To evaluate the ultrastructural changes in the macula after successful repair of rhegmatogenous retinal detachment (RRD) using simultaneous spectral domain optical coherence tomography (sdOCT) and fundus autofluorescence (FAF) imaging and to perform functional correlations with microperimetry. Methods: Simultaneous sdOCT and FAF imaging were performed using a combined sdOCT-confocal scanning laser ophthalmoscope (cSLO) system. Microperimetry was performed in a subgroup of these patients. Results: 17 patients with macular-on RRD and 20 with macular-off RRD were recruited. sdOCT images revealed disruption of the external limiting membrane, inner segment/outer segment junction or the Verhoeff membrane in 16 eyes (43.2%). The presence of any or more of these disruptions was significantly associated with a poor postoperative best-corrected visual acuity (BCVA) (p<0.001). Patients with abnormal FAF were also associated with poor postoperative BCVA (p<0.001). However, there was a generally poor correspondence between the localisation of ultrastructural abnormalities as detected by sdOCT and FAF changes. Areas of decreased microperimetric sensitivity corresponded well with the ultrastructural changes and abnormal FAF. Conclusions: FAF changes may lag behind ultrastructural changes in the OCT, some of which may reverse with the passage of time. The present study demonstrates the ultrastructural changes assessed with simultaneous FAF and sdOCT and their relation with visual outcome.
Persistent Identifierhttp://hdl.handle.net/10722/90369
ISSN
2015 Impact Factor: 3.036
2015 SCImago Journal Rankings: 1.873
ISI Accession Number ID
Funding AgencyGrant Number
University Development Fund
LKS Faculty of Medicine
University of Hong Kong, Hong Kong
Funding Information:

The study is supported in part by the University Development Fund, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong.

References

 

DC FieldValueLanguage
dc.contributor.authorLai, WWen_HK
dc.contributor.authorLeung, GYOen_HK
dc.contributor.authorChan, CWSen_HK
dc.contributor.authorYeung, IYLen_HK
dc.contributor.authorWong, Den_HK
dc.date.accessioned2010-09-06T10:09:25Z-
dc.date.available2010-09-06T10:09:25Z-
dc.date.issued2010en_HK
dc.identifier.citationBritish Journal Of Ophthalmology, 2010, v. 94 n. 3, p. 311-318en_HK
dc.identifier.issn0007-1161en_HK
dc.identifier.urihttp://hdl.handle.net/10722/90369-
dc.description.abstractBackground/aims: To evaluate the ultrastructural changes in the macula after successful repair of rhegmatogenous retinal detachment (RRD) using simultaneous spectral domain optical coherence tomography (sdOCT) and fundus autofluorescence (FAF) imaging and to perform functional correlations with microperimetry. Methods: Simultaneous sdOCT and FAF imaging were performed using a combined sdOCT-confocal scanning laser ophthalmoscope (cSLO) system. Microperimetry was performed in a subgroup of these patients. Results: 17 patients with macular-on RRD and 20 with macular-off RRD were recruited. sdOCT images revealed disruption of the external limiting membrane, inner segment/outer segment junction or the Verhoeff membrane in 16 eyes (43.2%). The presence of any or more of these disruptions was significantly associated with a poor postoperative best-corrected visual acuity (BCVA) (p<0.001). Patients with abnormal FAF were also associated with poor postoperative BCVA (p<0.001). However, there was a generally poor correspondence between the localisation of ultrastructural abnormalities as detected by sdOCT and FAF changes. Areas of decreased microperimetric sensitivity corresponded well with the ultrastructural changes and abnormal FAF. Conclusions: FAF changes may lag behind ultrastructural changes in the OCT, some of which may reverse with the passage of time. The present study demonstrates the ultrastructural changes assessed with simultaneous FAF and sdOCT and their relation with visual outcome.en_HK
dc.languageengen_HK
dc.publisherBMJ Publishing Group. The Journal's web site is located at http://bjo.bmjjournals.com/en_HK
dc.relation.ispartofBritish Journal of Ophthalmologyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsBritish Journal of Ophthalmology. Copyright © B M J Publishing Group.en_HK
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshFemale-
dc.subject.meshFluorescein Angiography - methods-
dc.subject.meshRetinal Detachment - pathology - physiopathology - surgery-
dc.titleSimultaneous spectral domain OCT and fundus autofluorescence imaging of the macula and microperimetric correspondence after successful repair of rhegmatogenous retinal detachmenten_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0007-1161&volume=94&issue=3&spage=311&epage=318&date=2009&atitle=Simultaneous+spectral+domain+OCT+and+fundus+autofluorescence+imaging+of+the+macula+and+microperimetric+correspondence+after+successful+repair+of+rhegmatogenous+retinal+detachment.en_HK
dc.identifier.emailLai, WW: wicolai@hku.hken_HK
dc.identifier.emailWong, D: shdwong@hku.hken_HK
dc.identifier.authorityLai, WW=rp00531en_HK
dc.identifier.authorityWong, D=rp00516en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1136/bjo.2009.163584en_HK
dc.identifier.pmid19822917-
dc.identifier.scopuseid_2-s2.0-77949534905en_HK
dc.identifier.hkuros162502en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77949534905&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume94en_HK
dc.identifier.issue3en_HK
dc.identifier.spage311en_HK
dc.identifier.epage318en_HK
dc.identifier.eissn1468-2079-
dc.identifier.isiWOS:000275346200013-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridLai, WW=7402231098en_HK
dc.identifier.scopusauthoridLeung, GYO=36096934600en_HK
dc.identifier.scopusauthoridChan, CWS=36151685500en_HK
dc.identifier.scopusauthoridYeung, IYL=6701564831en_HK
dc.identifier.scopusauthoridWong, D=7401536078en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats