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Article: Comparison of postoperative intraocular pressure in patients with Densiron-68 vs conventional silicone oil: A case-control study

TitleComparison of postoperative intraocular pressure in patients with Densiron-68 vs conventional silicone oil: A case-control study
Authors
KeywordsDensiron-68
Intraocular pressure
Postoperative
Silicone oil
Issue Date2009
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/eye
Citation
Eye, 2009, v. 23 n. 1, p. 190-194 How to Cite?
AbstractA solution of perfluorohexyloctane and silicone oil with a specific gravity of 1.06 g/cm3 (Densiron-68) has similar properties as conventional silicone oil (SO) in terms of the shape of the bubble and its ability to act as an internal tamponade agent. We conducted a case-control study to compare the postoperative intraocular pressure (IOP) in patients treated with Densiron-68 with those treated with SO. Methods: Seventy-one eyes of 71 patients and 57 eyes of 57 patients who had received Densiron-68 and SO, respectively, were included in our study. Both groups were found to have matched for their preoperative comorbidities (diabetes, glaucoma, phakic status, and refractive errors). IOP at first day, between seventh and fourteenth day, and at 4 week postoperatively was recorded. Results: The mean IOP was higher in patients treated with Densiron-68 at day 1 and between seventh and fourteenth day postoperatively (P=0.05 and 0.01, respectively). By the 4th week, the IOP difference between the two groups was insignificant (P=0.17). The difference in the two groups could still be clinically significant and the raised IOP in Densiron-68 group was more difficult to treat in some cases.On day 1, nine eyes (12.7%) in the Densiron-68 group and two eyes (3.5%) in the SO group had IOP greater than 30 mmHg. At 4 weeks, IOP of more than 30 mmHg was seen in nine eyes (12.7%) in the Densiron-68-treated group and in one eye (1.8%) in the SO group. Conclusion: The use of Densiron-68 was associated with a higher IOP in the early postoperative period when compared with SO. © 2009 Macmillan Publishers Limited All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/90367
ISSN
2015 Impact Factor: 2.213
2015 SCImago Journal Rankings: 1.132
ISI Accession Number ID
References
Errata

 

DC FieldValueLanguage
dc.contributor.authorWong, Den_HK
dc.contributor.authorKumar, Ien_HK
dc.contributor.authorQuah, SAen_HK
dc.contributor.authorAli, Hen_HK
dc.contributor.authorValdeperas, Xen_HK
dc.contributor.authorRomano, MRen_HK
dc.date.accessioned2010-09-06T10:09:24Z-
dc.date.available2010-09-06T10:09:24Z-
dc.date.issued2009en_HK
dc.identifier.citationEye, 2009, v. 23 n. 1, p. 190-194en_HK
dc.identifier.issn0950-222Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/90367-
dc.description.abstractA solution of perfluorohexyloctane and silicone oil with a specific gravity of 1.06 g/cm3 (Densiron-68) has similar properties as conventional silicone oil (SO) in terms of the shape of the bubble and its ability to act as an internal tamponade agent. We conducted a case-control study to compare the postoperative intraocular pressure (IOP) in patients treated with Densiron-68 with those treated with SO. Methods: Seventy-one eyes of 71 patients and 57 eyes of 57 patients who had received Densiron-68 and SO, respectively, were included in our study. Both groups were found to have matched for their preoperative comorbidities (diabetes, glaucoma, phakic status, and refractive errors). IOP at first day, between seventh and fourteenth day, and at 4 week postoperatively was recorded. Results: The mean IOP was higher in patients treated with Densiron-68 at day 1 and between seventh and fourteenth day postoperatively (P=0.05 and 0.01, respectively). By the 4th week, the IOP difference between the two groups was insignificant (P=0.17). The difference in the two groups could still be clinically significant and the raised IOP in Densiron-68 group was more difficult to treat in some cases.On day 1, nine eyes (12.7%) in the Densiron-68 group and two eyes (3.5%) in the SO group had IOP greater than 30 mmHg. At 4 weeks, IOP of more than 30 mmHg was seen in nine eyes (12.7%) in the Densiron-68-treated group and in one eye (1.8%) in the SO group. Conclusion: The use of Densiron-68 was associated with a higher IOP in the early postoperative period when compared with SO. © 2009 Macmillan Publishers Limited All rights reserved.en_HK
dc.languageengen_HK
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/eyeen_HK
dc.relation.ispartofEyeen_HK
dc.subjectDensiron-68en_HK
dc.subjectIntraocular pressureen_HK
dc.subjectPostoperativeen_HK
dc.subjectSilicone oilen_HK
dc.subject.meshAntihypertensive Agents - therapeutic use-
dc.subject.meshIntraocular Pressure - drug effects-
dc.subject.meshPostoperative Complications - drug therapy-
dc.subject.meshRetinal Detachment - surgery-
dc.subject.meshSilicone Oils - therapeutic use-
dc.titleComparison of postoperative intraocular pressure in patients with Densiron-68 vs conventional silicone oil: A case-control studyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0950-222X&volume=23&issue=1&spage=190&epage=194&date=2007&atitle=Comparison+of+postoperative+intraocular+pressure+in+patients+with+Densiron-68+vs+conventional+silicone+oil:+a+case-control+studyen_HK
dc.identifier.emailWong, D: shdwong@hku.hken_HK
dc.identifier.authorityWong, D=rp00516en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1038/sj.eye.6703055en_HK
dc.identifier.pmid18064055-
dc.identifier.scopuseid_2-s2.0-58249124457en_HK
dc.identifier.hkuros152808en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-58249124457&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume23en_HK
dc.identifier.issue1en_HK
dc.identifier.spage190en_HK
dc.identifier.epage194en_HK
dc.identifier.isiWOS:000262488100034-
dc.publisher.placeUnited Kingdomen_HK
dc.relation.erratumdoi:10.1038/eye.2008.94-
dc.identifier.scopusauthoridWong, D=7401536078en_HK
dc.identifier.scopusauthoridKumar, I=24171083400en_HK
dc.identifier.scopusauthoridQuah, SA=7003418735en_HK
dc.identifier.scopusauthoridAli, H=30267453300en_HK
dc.identifier.scopusauthoridValdeperas, X=25959391400en_HK
dc.identifier.scopusauthoridRomano, MR=35249070500en_HK
dc.identifier.citeulike2076287-

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