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Article: Effectiveness and safety of herbal medicines in the treatment of irritable bowel syndrome: A systematic review

TitleEffectiveness and safety of herbal medicines in the treatment of irritable bowel syndrome: A systematic review
Authors
KeywordsHerbal medicine
Irritable bowel syndrome
Systematic review
Issue Date2008
PublisherBaishideng Publishing Group. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htm
Citation
World Journal Of Gastroenterology, 2008, v. 14 n. 3, p. 454-462 How to Cite?
AbstractAim: To explore the efficacy and safety of herbal medicines (HM) in the treatment of irritable bowel syndrome (IBS). Methods: A computer-based as well as manual literature search was performed. We reviewed randomized controlled trials on the treatment of IBS with and without HM. Results: A total of 22 studies with 25 HMs met the inclusion criteria. Four of these studies were of good quality, while the remaining 18 studies involving 17 Chinese herbal medicine (CHM) formulas were of poor quality. Eight of these reports using 9 HMs showed global improvement of IBS symptoms, 4 studies with 3 HMs were efficacious in diarrhea-predominant IBS, and 2 studies with 2 HMs showed improvement in constipation-predominant IBS. Out of a total of 1279 patients, 15 adverse events in 47 subjects were reported with HM. No serious adverse events or abnormal laboratory tests were observed. The incidence of the adverse events was low (2.97%; 95% CI: 2.04%-3.90%). Conclusion: Herbal medicines have therapeutic benefit in IBS, and adverse events are seldom reported in literature. Nevertheless, herbal medicines should be used with caution. It is necessary to conduct rigorous, well-designed clinical trials to evaluate their effectiveness and safety in the treatment of IBS. © 2008 WJG. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/89668
ISSN
2015 Impact Factor: 2.787
2015 SCImago Journal Rankings: 1.076
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorShi, Jen_HK
dc.contributor.authorTong, Yen_HK
dc.contributor.authorShen, JGen_HK
dc.contributor.authorLi, HXen_HK
dc.date.accessioned2010-09-06T10:00:11Z-
dc.date.available2010-09-06T10:00:11Z-
dc.date.issued2008en_HK
dc.identifier.citationWorld Journal Of Gastroenterology, 2008, v. 14 n. 3, p. 454-462en_HK
dc.identifier.issn1007-9327en_HK
dc.identifier.urihttp://hdl.handle.net/10722/89668-
dc.description.abstractAim: To explore the efficacy and safety of herbal medicines (HM) in the treatment of irritable bowel syndrome (IBS). Methods: A computer-based as well as manual literature search was performed. We reviewed randomized controlled trials on the treatment of IBS with and without HM. Results: A total of 22 studies with 25 HMs met the inclusion criteria. Four of these studies were of good quality, while the remaining 18 studies involving 17 Chinese herbal medicine (CHM) formulas were of poor quality. Eight of these reports using 9 HMs showed global improvement of IBS symptoms, 4 studies with 3 HMs were efficacious in diarrhea-predominant IBS, and 2 studies with 2 HMs showed improvement in constipation-predominant IBS. Out of a total of 1279 patients, 15 adverse events in 47 subjects were reported with HM. No serious adverse events or abnormal laboratory tests were observed. The incidence of the adverse events was low (2.97%; 95% CI: 2.04%-3.90%). Conclusion: Herbal medicines have therapeutic benefit in IBS, and adverse events are seldom reported in literature. Nevertheless, herbal medicines should be used with caution. It is necessary to conduct rigorous, well-designed clinical trials to evaluate their effectiveness and safety in the treatment of IBS. © 2008 WJG. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherBaishideng Publishing Group. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htmen_HK
dc.relation.ispartofWorld Journal of Gastroenterologyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectHerbal medicineen_HK
dc.subjectIrritable bowel syndromeen_HK
dc.subjectSystematic reviewen_HK
dc.titleEffectiveness and safety of herbal medicines in the treatment of irritable bowel syndrome: A systematic reviewen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1007-9327&volume=Iss 14&issue=3&spage=454&epage=462&date=2008&atitle=Effectiveness+and+safety+of+herbal+medicines+in+the+treatment+of+irritable+bowel+syndrome:+A+systematic+review.en_HK
dc.identifier.emailTong, Y: tongyao@hku.hken_HK
dc.identifier.emailShen, JG: shenjg@hku.hken_HK
dc.identifier.authorityTong, Y=rp00509en_HK
dc.identifier.authorityShen, JG=rp00487en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3748/wjg.14.454en_HK
dc.identifier.pmid18200670-
dc.identifier.pmcidPMC2679136-
dc.identifier.scopuseid_2-s2.0-40049104748en_HK
dc.identifier.hkuros140231en_HK
dc.identifier.volume14en_HK
dc.identifier.issue3en_HK
dc.identifier.spage454en_HK
dc.identifier.epage462en_HK
dc.identifier.isiWOS:000252679500016-
dc.publisher.placeChinaen_HK
dc.identifier.scopusauthoridShi, J=7404495816en_HK
dc.identifier.scopusauthoridTong, Y=9045384000en_HK
dc.identifier.scopusauthoridShen, JG=7404929947en_HK
dc.identifier.scopusauthoridLi, HX=35083887800en_HK

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