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Article: Comparative study of Buyang Huanwu Decoction and the different combinations of its ingredients on neurogenesis following ischemic stroke in rats

TitleComparative study of Buyang Huanwu Decoction and the different combinations of its ingredients on neurogenesis following ischemic stroke in rats
Authors
Issue Date2007
PublisherZhongguo Zhong-Xiyi Jiehe Zazhi. The Journal's web site is located at http://zxyjh.periodicals.net.cn/
Citation
Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal Of Integrated Traditional And Western Medicine / Zhongguo Zhong Xi Yi Jie He Xue Hui, Zhongguo Zhong Yi Yan Jiu Yuan Zhu Ban, 2007, v. 27 n. 6, p. 519-522 How to Cite?
AbstractOBJECTIVE: To investigate the effect of Buyang Huanwu Decoction (BYHWD) and the different combinations of its ingredients on neurogenesis following ischemic stroke in rats. METHODS: The model rats of ischemic stroke was established by blocking cerebral media artery with electrocoagulation through craniectomy, and electric stimulation, given from 24 h after blocking, 2 h daily for 15 successive days. They were divided into four groups, Group A treated with saline, Group B treated with BYHWD, Group C treated with BYHWD but earthworm subtracted, and Group D treated with Danggui Buxue Decoction (DGBXD). The expression of 5-bromodeoxyuridine (BrdU) in cerebral tissue was determined by immunohistochemical method. RESULTS: Large amount of BrdU immunoreactive cells presented in the hippocampal region of rats in Group B and C, densely arranged, partial in cluster, with the figure significantly different to that in Group A (P < 0.01), and the amount in the ischemic side was significantly more than that in the opposite side (P < 0.05). While comparing between Group A and D, the amount of BrdU immunoreactive cells in the hippocampal region showed insignificant difference (P > 0.05). CONCLUSION: BYHWD has a effect in promoting neurogenesis better than DGBXD.
Persistent Identifierhttp://hdl.handle.net/10722/89633
ISSN
2015 SCImago Journal Rankings: 0.140

 

DC FieldValueLanguage
dc.contributor.authorTong, Len_HK
dc.contributor.authorTan, XHen_HK
dc.contributor.authorShen, JGen_HK
dc.date.accessioned2010-09-06T09:59:40Z-
dc.date.available2010-09-06T09:59:40Z-
dc.date.issued2007en_HK
dc.identifier.citationZhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal Of Integrated Traditional And Western Medicine / Zhongguo Zhong Xi Yi Jie He Xue Hui, Zhongguo Zhong Yi Yan Jiu Yuan Zhu Ban, 2007, v. 27 n. 6, p. 519-522en_HK
dc.identifier.issn1003-5370en_HK
dc.identifier.urihttp://hdl.handle.net/10722/89633-
dc.description.abstractOBJECTIVE: To investigate the effect of Buyang Huanwu Decoction (BYHWD) and the different combinations of its ingredients on neurogenesis following ischemic stroke in rats. METHODS: The model rats of ischemic stroke was established by blocking cerebral media artery with electrocoagulation through craniectomy, and electric stimulation, given from 24 h after blocking, 2 h daily for 15 successive days. They were divided into four groups, Group A treated with saline, Group B treated with BYHWD, Group C treated with BYHWD but earthworm subtracted, and Group D treated with Danggui Buxue Decoction (DGBXD). The expression of 5-bromodeoxyuridine (BrdU) in cerebral tissue was determined by immunohistochemical method. RESULTS: Large amount of BrdU immunoreactive cells presented in the hippocampal region of rats in Group B and C, densely arranged, partial in cluster, with the figure significantly different to that in Group A (P < 0.01), and the amount in the ischemic side was significantly more than that in the opposite side (P < 0.05). While comparing between Group A and D, the amount of BrdU immunoreactive cells in the hippocampal region showed insignificant difference (P > 0.05). CONCLUSION: BYHWD has a effect in promoting neurogenesis better than DGBXD.en_HK
dc.languageengen_HK
dc.publisherZhongguo Zhong-Xiyi Jiehe Zazhi. The Journal's web site is located at http://zxyjh.periodicals.net.cn/en_HK
dc.relation.ispartofZhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine / Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu banen_HK
dc.titleComparative study of Buyang Huanwu Decoction and the different combinations of its ingredients on neurogenesis following ischemic stroke in ratsen_HK
dc.typeArticleen_HK
dc.identifier.emailShen, JG: shenjg@hku.hken_HK
dc.identifier.authorityShen, JG=rp00487en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid17633364-
dc.identifier.scopuseid_2-s2.0-58149100061en_HK
dc.identifier.hkuros134590en_HK
dc.identifier.volume27en_HK
dc.identifier.issue6en_HK
dc.identifier.spage519en_HK
dc.identifier.epage522en_HK
dc.publisher.placeChinaen_HK
dc.identifier.scopusauthoridTong, L=7201891650en_HK
dc.identifier.scopusauthoridTan, XH=24068123000en_HK
dc.identifier.scopusauthoridShen, JG=7404929947en_HK

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