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Article: Tyrosinase inhibitors from paper mulberry (Broussonetia papyrifera)

TitleTyrosinase inhibitors from paper mulberry (Broussonetia papyrifera)
Authors
KeywordsBroussonetia papyrifera
Chalcone
Flavonol
Tyrosinase inhibition
Issue Date2008
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/foodchem
Citation
Food Chemistry, 2008, v. 106 n. 2, p. 529-535 How to Cite?
AbstractFractionation of a chloroform-soluble extract from twigs of Broussonetia papyrifera, led to the isolation of one new compound, 3,5,7,4′-tetrahydroxy-3′-(2-hydroxy-3-methylbut-3-enyl)flavone (1), and 10 known compounds, uralenol (2), quercetin (3), isolicoflavonol (4), papyriflavonol A (5), broussoflavonol F (6), 5,7,3′,5′-tetrahydroxyflavanone (7), luteolin (8), isoliquiritigenin (9), broussochalcone A (10) and 5,7,3′,4′-tetrahydroxy-3-methoxyflavone (11). Their structures were identified by interpretation of MS, 1H NMR, 13C NMR, HMQC and HMBC data. Their inhibitory activities on mushroom tyrosinase using l-tyrosine as substrate were investigated and the IC 50 values of 3,5,7,4′-tetrahydroxy-3′-(2-hydroxy-3-methylbut-3-enyl)flavone, uralenol, quercetin and broussoflavonol F were found to be 96.6, 49.5, 57.8, and 82.3 μM, respectively, better than arbutin, a well-known tyrosinase inhibitor. © 2007 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/89211
ISSN
2015 Impact Factor: 4.052
2015 SCImago Journal Rankings: 1.620
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorZheng, ZPen_HK
dc.contributor.authorCheng, KWen_HK
dc.contributor.authorChao, Jen_HK
dc.contributor.authorWu, Jen_HK
dc.contributor.authorWang, Men_HK
dc.date.accessioned2010-09-06T09:53:57Z-
dc.date.available2010-09-06T09:53:57Z-
dc.date.issued2008en_HK
dc.identifier.citationFood Chemistry, 2008, v. 106 n. 2, p. 529-535en_HK
dc.identifier.issn0308-8146en_HK
dc.identifier.urihttp://hdl.handle.net/10722/89211-
dc.description.abstractFractionation of a chloroform-soluble extract from twigs of Broussonetia papyrifera, led to the isolation of one new compound, 3,5,7,4′-tetrahydroxy-3′-(2-hydroxy-3-methylbut-3-enyl)flavone (1), and 10 known compounds, uralenol (2), quercetin (3), isolicoflavonol (4), papyriflavonol A (5), broussoflavonol F (6), 5,7,3′,5′-tetrahydroxyflavanone (7), luteolin (8), isoliquiritigenin (9), broussochalcone A (10) and 5,7,3′,4′-tetrahydroxy-3-methoxyflavone (11). Their structures were identified by interpretation of MS, 1H NMR, 13C NMR, HMQC and HMBC data. Their inhibitory activities on mushroom tyrosinase using l-tyrosine as substrate were investigated and the IC 50 values of 3,5,7,4′-tetrahydroxy-3′-(2-hydroxy-3-methylbut-3-enyl)flavone, uralenol, quercetin and broussoflavonol F were found to be 96.6, 49.5, 57.8, and 82.3 μM, respectively, better than arbutin, a well-known tyrosinase inhibitor. © 2007 Elsevier Ltd. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/foodchemen_HK
dc.relation.ispartofFood Chemistryen_HK
dc.rightsFood Chemistry . Copyright © Elsevier BV.en_HK
dc.subjectBroussonetia papyriferaen_HK
dc.subjectChalconeen_HK
dc.subjectFlavonolen_HK
dc.subjectTyrosinase inhibitionen_HK
dc.titleTyrosinase inhibitors from paper mulberry (Broussonetia papyrifera)en_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0308-8146&volume=106&issue=2&spage=529&epage=535&date=2008&atitle=Tyrosinase+inhibitors+from+paper+mulberry+(Broussonetia+papyrifera)en_HK
dc.identifier.emailWang, M: mfwang@hku.hken_HK
dc.identifier.authorityWang, M=rp00800en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.foodchem.2007.06.037en_HK
dc.identifier.scopuseid_2-s2.0-34548255352en_HK
dc.identifier.hkuros142339en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34548255352&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume106en_HK
dc.identifier.issue2en_HK
dc.identifier.spage529en_HK
dc.identifier.epage535en_HK
dc.identifier.isiWOS:000250038400013-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridZheng, ZP=8451746600en_HK
dc.identifier.scopusauthoridCheng, KW=12141247000en_HK
dc.identifier.scopusauthoridChao, J=24558959000en_HK
dc.identifier.scopusauthoridWu, J=8298828200en_HK
dc.identifier.scopusauthoridWang, M=7406691844en_HK

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