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Article: Multiple Actions of Secretin in the Human Body

TitleMultiple Actions of Secretin in the Human Body
Authors
KeywordsBrain
Gastrointestinal tract
Hypothalamus
Kidney
Pituitary
Secretin
Issue Date2008
PublisherAcademic Press.
Citation
International Review Of Cytology, 2008, v. 265, p. 159-190 How to Cite?
AbstractThe discovery of secretin initiated the field of endocrinology. Over the past century, multiple gastrointestinal functions of secretin have been extensively studied, and it was discovered that the principal function of this peptide in the gastrointestinal system is to facilitate digestion and to provide protection. In view of the late identification of secretin and the secretin receptor in various tissues, including the central nervous system, the pleiotropic functions of secretin have more recently been an area of intense focus. Secretin is a classical hormone, and recent studies clearly showed secretin's involvement in neural and neuroendocrine pathways, although the neuroactivity and neural regulation of its release are yet to be elucidated. This chapter reviews our current understanding of the pleiotropic actions of secretin with a special focus on the hormonal and neural interdependent pathways that mediate these actions. © 2008 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/89208
ISSN
2012 Impact Factor: -999.999
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLam, IPYen_HK
dc.contributor.authorSiu, FKYen_HK
dc.contributor.authorChu, JYSen_HK
dc.contributor.authorChow, BKCen_HK
dc.date.accessioned2010-09-06T09:53:54Z-
dc.date.available2010-09-06T09:53:54Z-
dc.date.issued2008en_HK
dc.identifier.citationInternational Review Of Cytology, 2008, v. 265, p. 159-190en_HK
dc.identifier.issn0074-7696en_HK
dc.identifier.urihttp://hdl.handle.net/10722/89208-
dc.description.abstractThe discovery of secretin initiated the field of endocrinology. Over the past century, multiple gastrointestinal functions of secretin have been extensively studied, and it was discovered that the principal function of this peptide in the gastrointestinal system is to facilitate digestion and to provide protection. In view of the late identification of secretin and the secretin receptor in various tissues, including the central nervous system, the pleiotropic functions of secretin have more recently been an area of intense focus. Secretin is a classical hormone, and recent studies clearly showed secretin's involvement in neural and neuroendocrine pathways, although the neuroactivity and neural regulation of its release are yet to be elucidated. This chapter reviews our current understanding of the pleiotropic actions of secretin with a special focus on the hormonal and neural interdependent pathways that mediate these actions. © 2008 Elsevier Inc. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherAcademic Press.en_HK
dc.relation.ispartofInternational Review of Cytologyen_HK
dc.subjectBrainen_HK
dc.subjectGastrointestinal tracten_HK
dc.subjectHypothalamusen_HK
dc.subjectKidneyen_HK
dc.subjectPituitaryen_HK
dc.subjectSecretinen_HK
dc.titleMultiple Actions of Secretin in the Human Bodyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0074-7696&volume=265&spage=159&epage=190&date=2008&atitle=Multiple+actions+of+secretin+in+the+human+bodyen_HK
dc.identifier.emailChu, JYS: hitan@graduate.hku.hken_HK
dc.identifier.emailChow, BKC: bkcc@hku.hken_HK
dc.identifier.authorityChu, JYS=rp00684en_HK
dc.identifier.authorityChow, BKC=rp00681en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0074-7696(07)65004-9en_HK
dc.identifier.pmid18275888-
dc.identifier.scopuseid_2-s2.0-38949106118en_HK
dc.identifier.hkuros143916en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-38949106118&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume265en_HK
dc.identifier.spage159en_HK
dc.identifier.epage190en_HK
dc.identifier.isiWOS:000253888700004-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLam, IPY=14050702700en_HK
dc.identifier.scopusauthoridSiu, FKY=6701518484en_HK
dc.identifier.scopusauthoridChu, JYS=34975209300en_HK
dc.identifier.scopusauthoridChow, BKC=7102826193en_HK

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