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Article: Mechanisms of reorganization of cell-cell junctions in the testis

TitleMechanisms of reorganization of cell-cell junctions in the testis
Authors
KeywordsCell Junction
Post-Transcription
Post-Translation
Regulation
Review
Spermatogenesis
Testis
Transcription
Issue Date2008
PublisherFrontiers in Bioscience. The Journal's web site is located at http://www.frontbiosci.org/
Citation
Frontiers In Bioscience, 2008, v. 13 n. 17, p. 6775-6786 How to Cite?
AbstractDuring spermatogenesis, intercellular junctions are dynamically remodeled to facilitate the translocation of developing germ cells from the basal to the adluminal compartment of the seminiferous epithelium. In particular, at stage VIII of the seminiferous epithelial cycle, timely restructuring of cell junctions localized at the blood-testis barrier and apical ectoplasmic specializations are crucial to allow the entry of preleptotene/leptotene spermatocytes to the adluminal compartment for further development and the release of mature spermatids from the epithelium respectively. In this review, the transcriptional, posttranscriptional and post-translational regulations involved in testicular cell junction restructuring are included and specific areas required further attention are also highlighted.
Persistent Identifierhttp://hdl.handle.net/10722/89199
ISSN
2015 Impact Factor: 2.484
2015 SCImago Journal Rankings: 1.583
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLui, WYen_HK
dc.contributor.authorLee, WMen_HK
dc.date.accessioned2010-09-06T09:53:47Z-
dc.date.available2010-09-06T09:53:47Z-
dc.date.issued2008en_HK
dc.identifier.citationFrontiers In Bioscience, 2008, v. 13 n. 17, p. 6775-6786en_HK
dc.identifier.issn1093-9946en_HK
dc.identifier.urihttp://hdl.handle.net/10722/89199-
dc.description.abstractDuring spermatogenesis, intercellular junctions are dynamically remodeled to facilitate the translocation of developing germ cells from the basal to the adluminal compartment of the seminiferous epithelium. In particular, at stage VIII of the seminiferous epithelial cycle, timely restructuring of cell junctions localized at the blood-testis barrier and apical ectoplasmic specializations are crucial to allow the entry of preleptotene/leptotene spermatocytes to the adluminal compartment for further development and the release of mature spermatids from the epithelium respectively. In this review, the transcriptional, posttranscriptional and post-translational regulations involved in testicular cell junction restructuring are included and specific areas required further attention are also highlighted.en_HK
dc.languageengen_HK
dc.publisherFrontiers in Bioscience. The Journal's web site is located at http://www.frontbiosci.org/en_HK
dc.relation.ispartofFrontiers in Bioscienceen_HK
dc.subjectCell Junctionen_HK
dc.subjectPost-Transcriptionen_HK
dc.subjectPost-Translationen_HK
dc.subjectRegulationen_HK
dc.subjectReviewen_HK
dc.subjectSpermatogenesisen_HK
dc.subjectTestisen_HK
dc.subjectTranscriptionen_HK
dc.titleMechanisms of reorganization of cell-cell junctions in the testisen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1093-9946&volume=13&spage=6775&epage=6786&date=2008&atitle=Mechanisms+of+reorganization+of+cell-cell+junctions+in+the+testisen_HK
dc.identifier.emailLui, WY: wylui@hku.hken_HK
dc.identifier.emailLee, WM: hrszlwm@hku.hken_HK
dc.identifier.authorityLui, WY=rp00756en_HK
dc.identifier.authorityLee, WM=rp00728en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.2741/3188-
dc.identifier.pmid18508694-
dc.identifier.scopuseid_2-s2.0-52049114644en_HK
dc.identifier.hkuros145112en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-52049114644&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume13en_HK
dc.identifier.issue17en_HK
dc.identifier.spage6775en_HK
dc.identifier.epage6786en_HK
dc.identifier.isiWOS:000255885000268-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLui, WY=35220192400en_HK
dc.identifier.scopusauthoridLee, WM=24799156600en_HK

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