Article: Vasopressin-independent mechanisms in controlling water homeostasis

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TitleVasopressin-independent mechanisms in controlling water homeostasis
AuthorsCheng, CYY1
Chu, JYS1
Chow, BKC1
Issue Date2009
PublisherSociety for Endocrinology. The Journal's web site is located at http://jme.endocrinology-journals.org/
CitationJournal Of Molecular Endocrinology, 2009, v. 43 n. 3, p. 81-92 [How to Cite?]
DOI: http://dx.doi.org/10.1677/JME-08-0123
AbstractThe maintenance of body water homeostasis depends on the balance between water intake and water excretion. In the kidney, vasopressin (Vp) is a critical regulator of water homeostasis by controlling the insertion of aquaporin 2 (AQP2) onto the apical membrane of the collecting duct principal cells in the short term and regulating the gene expression of AQP2 in the long term. A growing body of evidence from both in vitro and in vivo studies demonstrated that both secretin and oxytocin are involved as Vp-independent mechanisms regulating the renal water reabsorption process, including the translocation and expression of AQP2. This review focuses on how these two hormones are potentially involved as Vp-independent mechanisms in controlling water homeostasis. © 2009 Society for Endocrinology.
ISSN0952-5041
2011 Impact Factor: 3.485
2011 SCImago Journal Rankings: 0.345
DOIhttp://dx.doi.org/10.1677/JME-08-0123
ISI Accession Number IDWOS:000270477400001
Funding AgencyGrant Number
Research Grant Council HKU7501/05 M
7566/06
Funding Information:

This work was supported by a research grant from Research Grant Council HKU 7501/05 M and 7566/06 M to BKC Chow.

ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorCheng, CYY
dc.contributor.authorChu, JYS
dc.contributor.authorChow, BKC
dc.date.accessioned2010-09-06T09:53:44Z
dc.date.available2010-09-06T09:53:44Z
dc.date.issued2009
dc.description.abstractThe maintenance of body water homeostasis depends on the balance between water intake and water excretion. In the kidney, vasopressin (Vp) is a critical regulator of water homeostasis by controlling the insertion of aquaporin 2 (AQP2) onto the apical membrane of the collecting duct principal cells in the short term and regulating the gene expression of AQP2 in the long term. A growing body of evidence from both in vitro and in vivo studies demonstrated that both secretin and oxytocin are involved as Vp-independent mechanisms regulating the renal water reabsorption process, including the translocation and expression of AQP2. This review focuses on how these two hormones are potentially involved as Vp-independent mechanisms in controlling water homeostasis. © 2009 Society for Endocrinology.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationJournal Of Molecular Endocrinology, 2009, v. 43 n. 3, p. 81-92 [How to Cite?]
DOI: http://dx.doi.org/10.1677/JME-08-0123
dc.identifier.citeulike4498902
dc.identifier.doihttp://dx.doi.org/10.1677/JME-08-0123
dc.identifier.epage92
dc.identifier.hkuros162709
dc.identifier.isiWOS:000270477400001
Funding AgencyGrant Number
Research Grant Council HKU7501/05 M
7566/06
Funding Information:

This work was supported by a research grant from Research Grant Council HKU 7501/05 M and 7566/06 M to BKC Chow.

dc.identifier.issn0952-5041
2011 Impact Factor: 3.485
2011 SCImago Journal Rankings: 0.345
dc.identifier.issue3
dc.identifier.openurl
dc.identifier.pmid19318428
dc.identifier.scopuseid_2-s2.0-70350738250
dc.identifier.spage81
dc.identifier.urihttp://hdl.handle.net/10722/89196
dc.identifier.volume43
dc.languageeng
dc.publisherSociety for Endocrinology. The Journal's web site is located at http://jme.endocrinology-journals.org/
dc.publisher.placeUnited Kingdom
dc.relation.ispartofJournal of Molecular Endocrinology
dc.relation.referencesReferences in Scopus
dc.rightsJournal of Molecular Endocrinology. Copyright © Society for Endocrinology.
dc.titleVasopressin-independent mechanisms in controlling water homeostasis
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong