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- Publisher Website: 10.1016/S1521-6934(03)00094-4
- Scopus: eid_2-s2.0-0347022871
- PMID: 14614885
- WOS: WOS:000186840200004
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Article: Pathology of gestational trophoblastic diseases
Title | Pathology of gestational trophoblastic diseases |
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Authors | |
Keywords | Epithelioid trophoblastic tumour Intermediate trophoblast Pathology Trophoblast marker |
Issue Date | 2003 |
Publisher | Bailliere Tindall. The Journal's web site is located at http://www.elsevier.com/locate/bpobgyn |
Citation | Bailliere's Best Practice And Research In Clinical Obstetrics And Gynaecology, 2003, v. 17 n. 6, p. 849-868 How to Cite? |
Abstract | Gestational trophoblastic disease (GTD) is a heterogeneous group of diseases. This used to include partial and complete hydatidiform moles, invasive mole, choriocarcinoma and placental site trophoblastic tumour. In recent years, new entities, including epithelioid trophoblastic tumour, have been added to this family. Non-neoplastic and neoplastic lesions derived from implantation site and chorion intermediate trophoblast have been gaining attention in the literature. New markers for trophoblasts have been identified facilitating histological diagnosis in cases with unusual clinical or pathological features. It is worth noting that histological distinction between hydropic abortion and partial mole and between complete and partial moles, especially at early gestational age, may be difficult. It may not be possible to predict progress of the heterogeneous group of GTD from histopathological features, except probably in placental site trophoblastic tumour. Alternative biological markers may be explored for better patient management. |
Persistent Identifier | http://hdl.handle.net/10722/88737 |
ISSN | 2023 Impact Factor: 3.9 2023 SCImago Journal Rankings: 1.532 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
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dc.contributor.author | Cheung, ANY | en_HK |
dc.date.accessioned | 2010-09-06T09:47:19Z | - |
dc.date.available | 2010-09-06T09:47:19Z | - |
dc.date.issued | 2003 | en_HK |
dc.identifier.citation | Bailliere's Best Practice And Research In Clinical Obstetrics And Gynaecology, 2003, v. 17 n. 6, p. 849-868 | en_HK |
dc.identifier.issn | 1521-6934 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/88737 | - |
dc.description.abstract | Gestational trophoblastic disease (GTD) is a heterogeneous group of diseases. This used to include partial and complete hydatidiform moles, invasive mole, choriocarcinoma and placental site trophoblastic tumour. In recent years, new entities, including epithelioid trophoblastic tumour, have been added to this family. Non-neoplastic and neoplastic lesions derived from implantation site and chorion intermediate trophoblast have been gaining attention in the literature. New markers for trophoblasts have been identified facilitating histological diagnosis in cases with unusual clinical or pathological features. It is worth noting that histological distinction between hydropic abortion and partial mole and between complete and partial moles, especially at early gestational age, may be difficult. It may not be possible to predict progress of the heterogeneous group of GTD from histopathological features, except probably in placental site trophoblastic tumour. Alternative biological markers may be explored for better patient management. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Bailliere Tindall. The Journal's web site is located at http://www.elsevier.com/locate/bpobgyn | en_HK |
dc.relation.ispartof | Bailliere's Best Practice and Research in Clinical Obstetrics and Gynaecology | en_HK |
dc.subject | Epithelioid trophoblastic tumour | - |
dc.subject | Intermediate trophoblast | - |
dc.subject | Pathology | - |
dc.subject | Trophoblast marker | - |
dc.subject.mesh | Choriocarcinoma - pathology | en_HK |
dc.subject.mesh | Female | en_HK |
dc.subject.mesh | Gestational Trophoblastic Disease - classification - pathology | en_HK |
dc.subject.mesh | Humans | en_HK |
dc.subject.mesh | Hydatidiform Mole - pathology | en_HK |
dc.subject.mesh | Hydatidiform Mole, Invasive - pathology | en_HK |
dc.subject.mesh | Pregnancy | en_HK |
dc.subject.mesh | Prognosis | en_HK |
dc.subject.mesh | Trophoblastic Tumor, Placental Site - pathology | en_HK |
dc.subject.mesh | Trophoblasts - pathology | en_HK |
dc.subject.mesh | Uterine Neoplasms - pathology | en_HK |
dc.title | Pathology of gestational trophoblastic diseases | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1521-6934&volume=17&issue=6&spage=849&epage=868&date=2003&atitle=Pathology+of+gestational+trophoblastic+diseases | en_HK |
dc.identifier.email | Cheung, ANY:anycheun@hkucc.hku.hk | en_HK |
dc.identifier.authority | Cheung, ANY=rp00542 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/S1521-6934(03)00094-4 | en_HK |
dc.identifier.pmid | 14614885 | - |
dc.identifier.scopus | eid_2-s2.0-0347022871 | en_HK |
dc.identifier.hkuros | 86085 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0347022871&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 17 | en_HK |
dc.identifier.issue | 6 | en_HK |
dc.identifier.spage | 849 | en_HK |
dc.identifier.epage | 868 | en_HK |
dc.identifier.isi | WOS:000186840200004 | - |
dc.publisher.place | United Kingdom | en_HK |
dc.identifier.issnl | 1521-6934 | - |