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Article: Desmoplastic malignant melanoma on the buttock of an 18-year-old girl: Differentiation from desmoplastic nevus

TitleDesmoplastic malignant melanoma on the buttock of an 18-year-old girl: Differentiation from desmoplastic nevus
Authors
Issue Date1999
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.amjdermatopathology.com
Citation
American Journal Of Dermatopathology, 1999, v. 21 n. 2, p. 170-173 How to Cite?
AbstractMelanocytic proliferation in young people may sometimes pose a diagnostic dilemma. This is particularly so when a desmoplastic component is present. Because the two main differential diagnoses, desmoplastic malignant melanoma and desmoplastic Spitz nevus, share some morphologic features, the diagnosis of desmoplastic malignant melanoma may be overlooked. Distinction between the two is important because they show completely different biological behavior. The age of patient, site of lesion, histologic findings of melanocytic atypia, neurotropism, mitosis, and maturation help to distinguish the two entities. We report a case of desmoplastic malignant melanoma occurring in the buttock of an 18-year-old Chinese girl. Histologically, it had typical features of desmoplastic malignant melanoma with junctional melanocytic atypia and prominent neurotropism. Clinical and histologic differences between desmoplastic malignant melanoma and desmoplastic Spitz nevus are reviewed. We conclude that although desmoplastic Spitz nevus occurs much more commonly in adolescents, desmoplastic malignant melanoma can occur in this age group and even in non-sun-exposed skin. Microscopic findings remain the mainstay that guides the final diagnosis.
Persistent Identifierhttp://hdl.handle.net/10722/88379
ISSN
2015 Impact Factor: 1.396
2015 SCImago Journal Rankings: 0.632
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, GSWen_HK
dc.contributor.authorChoy, Cen_HK
dc.contributor.authorNg, WKen_HK
dc.contributor.authorChan, KWen_HK
dc.date.accessioned2010-09-06T09:42:36Z-
dc.date.available2010-09-06T09:42:36Z-
dc.date.issued1999en_HK
dc.identifier.citationAmerican Journal Of Dermatopathology, 1999, v. 21 n. 2, p. 170-173en_HK
dc.identifier.issn0193-1091en_HK
dc.identifier.urihttp://hdl.handle.net/10722/88379-
dc.description.abstractMelanocytic proliferation in young people may sometimes pose a diagnostic dilemma. This is particularly so when a desmoplastic component is present. Because the two main differential diagnoses, desmoplastic malignant melanoma and desmoplastic Spitz nevus, share some morphologic features, the diagnosis of desmoplastic malignant melanoma may be overlooked. Distinction between the two is important because they show completely different biological behavior. The age of patient, site of lesion, histologic findings of melanocytic atypia, neurotropism, mitosis, and maturation help to distinguish the two entities. We report a case of desmoplastic malignant melanoma occurring in the buttock of an 18-year-old Chinese girl. Histologically, it had typical features of desmoplastic malignant melanoma with junctional melanocytic atypia and prominent neurotropism. Clinical and histologic differences between desmoplastic malignant melanoma and desmoplastic Spitz nevus are reviewed. We conclude that although desmoplastic Spitz nevus occurs much more commonly in adolescents, desmoplastic malignant melanoma can occur in this age group and even in non-sun-exposed skin. Microscopic findings remain the mainstay that guides the final diagnosis.en_HK
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.amjdermatopathology.comen_HK
dc.relation.ispartofAmerican Journal of Dermatopathologyen_HK
dc.rightsAmerican Journal of Dermatopathology. Copyright © Lippincott Williams & Wilkins.en_HK
dc.subject.meshAdulten_HK
dc.subject.meshButtocksen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMelanoma - pathologyen_HK
dc.subject.meshNevus, Epithelioid and Spindle Cell - pathologyen_HK
dc.subject.meshSkin Neoplasms - pathologyen_HK
dc.titleDesmoplastic malignant melanoma on the buttock of an 18-year-old girl: Differentiation from desmoplastic nevusen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0193-1091&volume=21&issue=2&spage=170&epage=173&date=1999&atitle=Desmoplastic+malignant+melanoma+on+the+buttock+of+an+18-year-old+girl:+differentiation+from+desmoplastic+nevusen_HK
dc.identifier.emailChan, KW:hrmtckw@hku.hken_HK
dc.identifier.authorityChan, KW=rp00330en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/00000372-199904000-00011en_HK
dc.identifier.pmid10218679-
dc.identifier.scopuseid_2-s2.0-0032963723en_HK
dc.identifier.hkuros44972en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032963723&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume21en_HK
dc.identifier.issue2en_HK
dc.identifier.spage170en_HK
dc.identifier.epage173en_HK
dc.identifier.isiWOS:000079553700011-
dc.publisher.placeUnited Statesen_HK

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