File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Diagnostic yield of bronchoscopic sampling methods in bronchial carcinoma

TitleDiagnostic yield of bronchoscopic sampling methods in bronchial carcinoma
Authors
KeywordsBronchial carcinoma
Bronchoalveolar lavage
Bronchoscopy
Diagnosis
Issue Date2000
PublisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/RES
Citation
Respirology, 2000, v. 5 n. 3, p. 265-270 How to Cite?
AbstractObjectives: The aim was to study the yield of malignant or suspicious cells from bronchoalveolar lavage (BAIL), endobronchial biopsy (BX) and endobronchial brushing (BR) specimens obtained at bronchoscopy. Methodology: We prospectively followed up all patients who had undergone bronchoscopy and studied those with subsequent diagnosis of bronchial carcinoma at a tertiary referral chondri. Bronchoalveolar lavage, BX and BR were performed, sequentially whenever possible, by one pulmonologist. The parameters assessed were age, gender, macroscopic bronchoscopic findings, TNM staging, radiological findings, histological typing, and diagnostic yield from BAL, BX, and BR. Results: One hundred patients (31 females, 69 males; mean age ± SD, 61.8 ± 12.7 years; range 32-81 years) were studied between 1995 and 1997. Of these, BAL, BX and BR were performed on 100, 64 and 37 cases which yielded diagnostic specimens for bronchial carcinoma in 69, 78.1, and 62.2% of cases, respectively (P> 0.05). Diagnostic specimens were therefore obtained in 69, 50, and 23% of the entire patient cohort from BAL, BX, and BR, respectively (P< 0.001). The diagnostic yield of BAL was independent of patient age, gender, site of lesion, TNM staging, histological typing and macroscopic bronchoscopic findings. Addition of BX, BR and postbronchoscopic sputum sampling to BAL only increased the yield of diagnostic specimens for bronchial carcinoma by 7, 0, and 4%, respectively. Conclusion: Bronchoalveolar lavage is a highly effective sampling method to obtain cytological evidence for bronchial carcinoma. The diagnostic yield for BAL is independent of tumour or other clinical characteristics. Further studies should be performed to confirm these important and clinically relevant findings.
Persistent Identifierhttp://hdl.handle.net/10722/88306
ISSN
2015 Impact Factor: 3.078
2015 SCImago Journal Rankings: 1.157
References

 

DC FieldValueLanguage
dc.contributor.authorLam, Ben_HK
dc.contributor.authorWong, MPen_HK
dc.contributor.authorOoi, Cen_HK
dc.contributor.authorLam, WKen_HK
dc.contributor.authorChan, KNen_HK
dc.contributor.authorHo, JCen_HK
dc.contributor.authorTsang, KWen_HK
dc.date.accessioned2010-09-06T09:41:39Z-
dc.date.available2010-09-06T09:41:39Z-
dc.date.issued2000en_HK
dc.identifier.citationRespirology, 2000, v. 5 n. 3, p. 265-270en_HK
dc.identifier.issn1323-7799en_HK
dc.identifier.urihttp://hdl.handle.net/10722/88306-
dc.description.abstractObjectives: The aim was to study the yield of malignant or suspicious cells from bronchoalveolar lavage (BAIL), endobronchial biopsy (BX) and endobronchial brushing (BR) specimens obtained at bronchoscopy. Methodology: We prospectively followed up all patients who had undergone bronchoscopy and studied those with subsequent diagnosis of bronchial carcinoma at a tertiary referral chondri. Bronchoalveolar lavage, BX and BR were performed, sequentially whenever possible, by one pulmonologist. The parameters assessed were age, gender, macroscopic bronchoscopic findings, TNM staging, radiological findings, histological typing, and diagnostic yield from BAL, BX, and BR. Results: One hundred patients (31 females, 69 males; mean age ± SD, 61.8 ± 12.7 years; range 32-81 years) were studied between 1995 and 1997. Of these, BAL, BX and BR were performed on 100, 64 and 37 cases which yielded diagnostic specimens for bronchial carcinoma in 69, 78.1, and 62.2% of cases, respectively (P> 0.05). Diagnostic specimens were therefore obtained in 69, 50, and 23% of the entire patient cohort from BAL, BX, and BR, respectively (P< 0.001). The diagnostic yield of BAL was independent of patient age, gender, site of lesion, TNM staging, histological typing and macroscopic bronchoscopic findings. Addition of BX, BR and postbronchoscopic sputum sampling to BAL only increased the yield of diagnostic specimens for bronchial carcinoma by 7, 0, and 4%, respectively. Conclusion: Bronchoalveolar lavage is a highly effective sampling method to obtain cytological evidence for bronchial carcinoma. The diagnostic yield for BAL is independent of tumour or other clinical characteristics. Further studies should be performed to confirm these important and clinically relevant findings.en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/RESen_HK
dc.relation.ispartofRespirologyen_HK
dc.subjectBronchial carcinomaen_HK
dc.subjectBronchoalveolar lavageen_HK
dc.subjectBronchoscopyen_HK
dc.subjectDiagnosisen_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshAged, 80 and overen_HK
dc.subject.meshBiopsy - methodsen_HK
dc.subject.meshBronchoalveolar Lavage - methodsen_HK
dc.subject.meshBronchoscopy - methodsen_HK
dc.subject.meshCarcinoma, Bronchogenic - pathology - radiographyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshLung Neoplasms - pathology - radiographyen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshNeoplasm Stagingen_HK
dc.subject.meshProspective Studiesen_HK
dc.subject.meshRadiography, Thoracicen_HK
dc.subject.meshTomography, X-Ray Computeden_HK
dc.titleDiagnostic yield of bronchoscopic sampling methods in bronchial carcinomaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1323-7799&volume=5&issue=3&spage=265&epage=270&date=2000&atitle=Diagnostic+yield+of+bronchoscopic+sampling+methods+in+bronchial+carcinomaen_HK
dc.identifier.emailWong, MP:mwpik@hkucc.hku.hken_HK
dc.identifier.emailHo, JC:jhocm@hku.hken_HK
dc.identifier.authorityWong, MP=rp00348en_HK
dc.identifier.authorityHo, JC=rp00258en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1046/j.1440-1843.2000.00258.xen_HK
dc.identifier.pmid11022989-
dc.identifier.scopuseid_2-s2.0-0033801863en_HK
dc.identifier.hkuros67813en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0033801863&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume5en_HK
dc.identifier.issue3en_HK
dc.identifier.spage265en_HK
dc.identifier.epage270en_HK
dc.publisher.placeAustraliaen_HK
dc.identifier.scopusauthoridLam, B=9246012800en_HK
dc.identifier.scopusauthoridWong, MP=7403907887en_HK
dc.identifier.scopusauthoridOoi, C=18837726600en_HK
dc.identifier.scopusauthoridLam, WK=7203021937en_HK
dc.identifier.scopusauthoridChan, KN=15737866400en_HK
dc.identifier.scopusauthoridHo, JC=7402649981en_HK
dc.identifier.scopusauthoridTsang, KW=7201555024en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats