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Article: Unexpected intrauterine death following resolution of hydrops fetalis after betamethasone treatment in a fetus with a large cystic adenomatoid malformation of the lung

TitleUnexpected intrauterine death following resolution of hydrops fetalis after betamethasone treatment in a fetus with a large cystic adenomatoid malformation of the lung
Authors
KeywordsBetamethasone
CAML
Corticosteroid therapy
Cystic adenomatoid malformation
Fetal lung lesion
Hydrops
Issue Date2005
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0960-7692/
Citation
Ultrasound In Obstetrics And Gynecology, 2005, v. 25 n. 6, p. 610-612 How to Cite?
AbstractWithout intervention, the development of hydrops fetalis secondary to cystic adenomatoid malformation of the lung (CAML) implies a 100% mortality rate. Conversely, four CAML cases with in-utero resolution of hydrops fetalis after prenatal betamethasone therapy with good clinical outcome have been reported in the literature. The mechanism is speculated to be the effect of corticosteroid in improving lung maturation. Here we present another CAML case with resolution of hydrops fetalis after prenatal betamethasone therapy but which was followed by later intrauterine death. We speculate that the resolution of the CAML lesion itself may be more important in determining the clinical outcome than the resolution of hydrops. The association between prenatal betamethasone therapy and resolution of hydrops may be related to a different mechanism other than improvement of lung maturation. Copyright © 2005 ISUOG. Published by John Wiley & Sons, Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/87446
ISSN
2015 Impact Factor: 4.197
2015 SCImago Journal Rankings: 1.766
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLeung, WCen_HK
dc.contributor.authorNgai, Cen_HK
dc.contributor.authorLam, TPWen_HK
dc.contributor.authorChan, KLen_HK
dc.contributor.authorLao, TTen_HK
dc.contributor.authorTang, MHYen_HK
dc.date.accessioned2010-09-06T09:29:46Z-
dc.date.available2010-09-06T09:29:46Z-
dc.date.issued2005en_HK
dc.identifier.citationUltrasound In Obstetrics And Gynecology, 2005, v. 25 n. 6, p. 610-612en_HK
dc.identifier.issn0960-7692en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87446-
dc.description.abstractWithout intervention, the development of hydrops fetalis secondary to cystic adenomatoid malformation of the lung (CAML) implies a 100% mortality rate. Conversely, four CAML cases with in-utero resolution of hydrops fetalis after prenatal betamethasone therapy with good clinical outcome have been reported in the literature. The mechanism is speculated to be the effect of corticosteroid in improving lung maturation. Here we present another CAML case with resolution of hydrops fetalis after prenatal betamethasone therapy but which was followed by later intrauterine death. We speculate that the resolution of the CAML lesion itself may be more important in determining the clinical outcome than the resolution of hydrops. The association between prenatal betamethasone therapy and resolution of hydrops may be related to a different mechanism other than improvement of lung maturation. Copyright © 2005 ISUOG. Published by John Wiley & Sons, Ltd.en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0960-7692/en_HK
dc.relation.ispartofUltrasound in Obstetrics and Gynecologyen_HK
dc.rightsUltrasound in Obstetrics & Gynecology. Copyright © John Wiley & Sons Ltd.en_HK
dc.subjectBetamethasoneen_HK
dc.subjectCAMLen_HK
dc.subjectCorticosteroid therapyen_HK
dc.subjectCystic adenomatoid malformationen_HK
dc.subjectFetal lung lesionen_HK
dc.subjectHydropsen_HK
dc.titleUnexpected intrauterine death following resolution of hydrops fetalis after betamethasone treatment in a fetus with a large cystic adenomatoid malformation of the lungen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0960-7692&volume=25&spage=610&epage=612&date=2005&atitle=Unexpected+intrauterine+death+following+resolution+of+hydrops+fetalis+after+betamethasone+treatment+in+a+fetus+with+a+large+cystic+adenomatoid+malformation+of+the+lungen_HK
dc.identifier.emailTang, MHY: mhytang@hkucc.hku.hken_HK
dc.identifier.authorityTang, MHY=rp01701en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/uog.1912en_HK
dc.identifier.pmid15912480-
dc.identifier.scopuseid_2-s2.0-20644465404en_HK
dc.identifier.hkuros98743en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-20644465404&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume25en_HK
dc.identifier.issue6en_HK
dc.identifier.spage610en_HK
dc.identifier.epage612en_HK
dc.identifier.isiWOS:000229812000016-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridLeung, WC=7201504435en_HK
dc.identifier.scopusauthoridNgai, C=6603676357en_HK
dc.identifier.scopusauthoridLam, TPW=36103835400en_HK
dc.identifier.scopusauthoridChan, KL=37004089600en_HK
dc.identifier.scopusauthoridLao, TT=7005722132en_HK
dc.identifier.scopusauthoridTang, MHY=8943401300en_HK
dc.identifier.citeulike215268-

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