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Article: Reducing the induction to abortion interval in termination of second trimester pregnancies: A comparison of mifepristone with laminaria tent

TitleReducing the induction to abortion interval in termination of second trimester pregnancies: A comparison of mifepristone with laminaria tent
Authors
Issue Date1995
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/BJOG
Citation
British Journal Of Obstetrics And Gynaecology, 1995, v. 102 n. 8, p. 648-651 How to Cite?
AbstractObjective: To determine whether mifepristone (RU486) is more effective than laminaria tent in shortening the induction-abortion interval in termination of second trimester pregnancies with gemeprost. Design: Prospective randomised comparative trial. Setting: Department of Obstetrics and Gynaecology in a University teaching hospital. Subjects: Sixty-two women undergoing termination of pregnancy in the second trimester. Interventions: The women were allocated at random to one of the two treatment groups. The first group received 600 mg of mifepristone 36 h before administration of gemeprost. In the second group, a medium-sized laminaria tent was inserted 12 h before gemeprost. The pregnancies in both groups were terminated with vaginal gemeprost, 1 mg every 3 h up to a maximum of 5 mg/day. Main outcome measures: Induction-abortion intervals, amount of gemeprost required, and incidence of side effects. Results: The median induction-abortion interval in the mifepristone group (7.5 h) was significantly shorter than that in the laminaria tent group (11 h) and significantly fewer gemeprost pessaries were required. There was no significant difference in the amount of narcotic analgesics required or the incidence of side effects between the two groups. Conclusions: Mifepristone is more effective than laminaria tent in shortening the induction-abortion interval in termination of second trimester pregnancies.
Persistent Identifierhttp://hdl.handle.net/10722/87378
ISSN
2001 Impact Factor: 2.321
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHo, PCen_HK
dc.contributor.authorTsang, SSKen_HK
dc.contributor.authorMa, HKen_HK
dc.date.accessioned2010-09-06T09:28:55Z-
dc.date.available2010-09-06T09:28:55Z-
dc.date.issued1995en_HK
dc.identifier.citationBritish Journal Of Obstetrics And Gynaecology, 1995, v. 102 n. 8, p. 648-651en_HK
dc.identifier.issn0306-5456en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87378-
dc.description.abstractObjective: To determine whether mifepristone (RU486) is more effective than laminaria tent in shortening the induction-abortion interval in termination of second trimester pregnancies with gemeprost. Design: Prospective randomised comparative trial. Setting: Department of Obstetrics and Gynaecology in a University teaching hospital. Subjects: Sixty-two women undergoing termination of pregnancy in the second trimester. Interventions: The women were allocated at random to one of the two treatment groups. The first group received 600 mg of mifepristone 36 h before administration of gemeprost. In the second group, a medium-sized laminaria tent was inserted 12 h before gemeprost. The pregnancies in both groups were terminated with vaginal gemeprost, 1 mg every 3 h up to a maximum of 5 mg/day. Main outcome measures: Induction-abortion intervals, amount of gemeprost required, and incidence of side effects. Results: The median induction-abortion interval in the mifepristone group (7.5 h) was significantly shorter than that in the laminaria tent group (11 h) and significantly fewer gemeprost pessaries were required. There was no significant difference in the amount of narcotic analgesics required or the incidence of side effects between the two groups. Conclusions: Mifepristone is more effective than laminaria tent in shortening the induction-abortion interval in termination of second trimester pregnancies.en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/BJOGen_HK
dc.relation.ispartofBritish Journal of Obstetrics and Gynaecologyen_HK
dc.rightsBritish Journal of Obstetrics & Gynaecology. Copyright © Blackwell Publishing Ltd.en_HK
dc.titleReducing the induction to abortion interval in termination of second trimester pregnancies: A comparison of mifepristone with laminaria tenten_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0306-5456&volume=102&spage=648&epage=651&date=1995&atitle=Reducing+the+induction+to+abortion+interval+in+termination+of+second+trimester+pregnancies:+a+comparison+of+mifepristone+with+laminaria+tenten_HK
dc.identifier.emailHo, PC:pcho@hku.hken_HK
dc.identifier.authorityHo, PC=rp00325en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid7654644-
dc.identifier.scopuseid_2-s2.0-0029147551en_HK
dc.identifier.hkuros15126en_HK
dc.identifier.volume102en_HK
dc.identifier.issue8en_HK
dc.identifier.spage648en_HK
dc.identifier.epage651en_HK
dc.identifier.isiWOS:A1995RN02900011-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridHo, PC=7402211440en_HK
dc.identifier.scopusauthoridTsang, SSK=7102255948en_HK
dc.identifier.scopusauthoridMa, HK=7403095603en_HK

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