File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Vaginal misoprostol compared with oral misoprostol in termination of second-trimester pregnancy

TitleVaginal misoprostol compared with oral misoprostol in termination of second-trimester pregnancy
Authors
Issue Date1997
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.greenjournal.org
Citation
Obstetrics And Gynecology, 1997, v. 90 n. 5, p. 735-738 How to Cite?
AbstractObjective: To compare the efficacy of vaginal with oral misoprostol in termination of second-trimester pregnancy after pretreatment with mifepristone. Methods: Women requesting termination of second-trimester pregnancy were randomized into two groups. Thirty-six to 48 hours after oral administration of 200 mg of mifepristone, women were given either oral or vaginal misoprostol 200 μg every 3 hours for a maximum of five doses in the first 24 hours. Women receiving oral misoprostol also were given a vaginal placebo (vitamin B6), whereas those receiving vaginal misoprostol were given an oral placebo. If they failed to abort, a second course was given by the same route. Results: The median induction-abortion interval in the vaginal group (9 hours) was significantly shorter than that in the oral group (13 hours). The percentage of women aborting within 24 hours in the vaginal group (90%) was significantly higher than that in the oral group (69%). The median amount of misoprostol used in the vaginal group (600 μg) also was significantly less than that in the oral group (1000 μg). There was no significant difference in the incidence of side effects between the two groups except for fatigue and breast tenderness, which were more common in the oral group. Seventy-six percent of the women preferred the oral route, and 24.5% of the women preferred the vaginal route. Conclusion: Vaginal misoprostol is more effective than oral misoprostol in termination of second- trimester pregnancy after pretreatment with mifepristone, but more women preferred the oral route.
Persistent Identifierhttp://hdl.handle.net/10722/87374
ISSN
2015 Impact Factor: 5.656
2015 SCImago Journal Rankings: 2.899
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHo, PCen_HK
dc.contributor.authorNgai, SWen_HK
dc.contributor.authorLiu, KLen_HK
dc.contributor.authorWong, GCYen_HK
dc.contributor.authorLee, SWHen_HK
dc.date.accessioned2010-09-06T09:28:51Z-
dc.date.available2010-09-06T09:28:51Z-
dc.date.issued1997en_HK
dc.identifier.citationObstetrics And Gynecology, 1997, v. 90 n. 5, p. 735-738en_HK
dc.identifier.issn0029-7844en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87374-
dc.description.abstractObjective: To compare the efficacy of vaginal with oral misoprostol in termination of second-trimester pregnancy after pretreatment with mifepristone. Methods: Women requesting termination of second-trimester pregnancy were randomized into two groups. Thirty-six to 48 hours after oral administration of 200 mg of mifepristone, women were given either oral or vaginal misoprostol 200 μg every 3 hours for a maximum of five doses in the first 24 hours. Women receiving oral misoprostol also were given a vaginal placebo (vitamin B6), whereas those receiving vaginal misoprostol were given an oral placebo. If they failed to abort, a second course was given by the same route. Results: The median induction-abortion interval in the vaginal group (9 hours) was significantly shorter than that in the oral group (13 hours). The percentage of women aborting within 24 hours in the vaginal group (90%) was significantly higher than that in the oral group (69%). The median amount of misoprostol used in the vaginal group (600 μg) also was significantly less than that in the oral group (1000 μg). There was no significant difference in the incidence of side effects between the two groups except for fatigue and breast tenderness, which were more common in the oral group. Seventy-six percent of the women preferred the oral route, and 24.5% of the women preferred the vaginal route. Conclusion: Vaginal misoprostol is more effective than oral misoprostol in termination of second- trimester pregnancy after pretreatment with mifepristone, but more women preferred the oral route.en_HK
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.greenjournal.orgen_HK
dc.relation.ispartofObstetrics and Gynecologyen_HK
dc.rightsObstetrics and Gynecology. Copyright © Lippincott Williams & Wilkins.en_HK
dc.titleVaginal misoprostol compared with oral misoprostol in termination of second-trimester pregnancyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0029-7844&volume=90&issue=5&spage=735&epage=738&date=1997&atitle=Vaginal+misoprostol+compared+with+oral+misoprostol+in+termination+of+second-trimester+pregnancyen_HK
dc.identifier.emailHo, PC:pcho@hku.hken_HK
dc.identifier.authorityHo, PC=rp00325en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0029-7844(97)00419-5en_HK
dc.identifier.pmid9351755-
dc.identifier.scopuseid_2-s2.0-0030801779en_HK
dc.identifier.hkuros30039en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0030801779&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume90en_HK
dc.identifier.issue5en_HK
dc.identifier.spage735en_HK
dc.identifier.epage738en_HK
dc.identifier.isiWOS:A1997YB81600007-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridHo, PC=7402211440en_HK
dc.identifier.scopusauthoridNgai, SW=7006074214en_HK
dc.identifier.scopusauthoridLiu, KL=7404200677en_HK
dc.identifier.scopusauthoridWong, GCY=17836958100en_HK
dc.identifier.scopusauthoridLee, SWH=26030998000en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats