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Article: Capillary electrophoresis-based immunoassay

TitleCapillary electrophoresis-based immunoassay
Authors
KeywordsCapillary electrophoresis
Immunoassays
Review
Issue Date2003
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/jchromb
Citation
Journal Of Chromatography B: Analytical Technologies In The Biomedical And Life Sciences, 2003, v. 797 n. 1-2, p. 217-228 How to Cite?
AbstractCapillary electrophoresis-based immunoassay (CEIA) is a developing analytical technique with a number of advantages over conventional immunoassay, such as reduced sample consumption, simpler procedure, easy simultaneous determination of multiple analytes, and short analysis time. However, there are still a number of technical issues that researchers on CEIA have to solve before the assay can be more widely used. These issues include method to improve the concentration sensitivity of the assay, requirement for robust separation strategy for different analytes, and method to increase the throughput of the assay. The approaches to solve these issues are reviewed. Several studies have been devoted to develop general separation strategies for CEIA, and to enhance the sensitivity of detection. The recent development of microchip-based CEIA is encouraging and is likely to address more drawbacks of CEIA, particularly on the throughput issue. © 2003 Elsevier B.V. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/87370
ISSN
2015 Impact Factor: 2.687
2015 SCImago Journal Rankings: 0.947
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYeung, WSBen_HK
dc.contributor.authorLuo, GAen_HK
dc.contributor.authorWang, QGen_HK
dc.contributor.authorOu, JPen_HK
dc.date.accessioned2010-09-06T09:28:47Z-
dc.date.available2010-09-06T09:28:47Z-
dc.date.issued2003en_HK
dc.identifier.citationJournal Of Chromatography B: Analytical Technologies In The Biomedical And Life Sciences, 2003, v. 797 n. 1-2, p. 217-228en_HK
dc.identifier.issn1570-0232en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87370-
dc.description.abstractCapillary electrophoresis-based immunoassay (CEIA) is a developing analytical technique with a number of advantages over conventional immunoassay, such as reduced sample consumption, simpler procedure, easy simultaneous determination of multiple analytes, and short analysis time. However, there are still a number of technical issues that researchers on CEIA have to solve before the assay can be more widely used. These issues include method to improve the concentration sensitivity of the assay, requirement for robust separation strategy for different analytes, and method to increase the throughput of the assay. The approaches to solve these issues are reviewed. Several studies have been devoted to develop general separation strategies for CEIA, and to enhance the sensitivity of detection. The recent development of microchip-based CEIA is encouraging and is likely to address more drawbacks of CEIA, particularly on the throughput issue. © 2003 Elsevier B.V. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/jchromben_HK
dc.relation.ispartofJournal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciencesen_HK
dc.rightsJournal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences. Copyright © Elsevier BV.en_HK
dc.subjectCapillary electrophoresisen_HK
dc.subjectImmunoassaysen_HK
dc.subjectReviewen_HK
dc.titleCapillary electrophoresis-based immunoassayen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1570-0232&volume=797&spage=217&epage=228&date=2003&atitle=Capillary+electrophoresis-based+immunoassayen_HK
dc.identifier.emailYeung, WSB:wsbyeung@hkucc.hku.hken_HK
dc.identifier.authorityYeung, WSB=rp00331en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S1570-0232(03)00489-6en_HK
dc.identifier.pmid14630151-
dc.identifier.scopuseid_2-s2.0-0242495502en_HK
dc.identifier.hkuros87485en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0242495502&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume797en_HK
dc.identifier.issue1-2en_HK
dc.identifier.spage217en_HK
dc.identifier.epage228en_HK
dc.identifier.isiWOS:000186844600013-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridYeung, WSB=7102370745en_HK
dc.identifier.scopusauthoridLuo, GA=7401536462en_HK
dc.identifier.scopusauthoridWang, QG=7406915351en_HK
dc.identifier.scopusauthoridOu, JP=7202845297en_HK

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