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Article: The effect of contraceptive pills on the measured blood loss in medical termination of pregnancy by mifepristone and misoprostol: A randomized placebo controlled trial

TitleThe effect of contraceptive pills on the measured blood loss in medical termination of pregnancy by mifepristone and misoprostol: A randomized placebo controlled trial
Authors
KeywordsMeasured blood loss
Mifepristone
Misoprostol
OC pills
Issue Date2002
PublisherOxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/
Citation
Human Reproduction, 2002, v. 17 n. 1, p. 99-102 How to Cite?
AbstractBackground: A prospective randomized placebo controlled trial was performed to assess the immediate use of oral contraceptive (OC) on the amount of blood loss in the post-abortion period in women undergoing medical abortion by mifepristone and misoprostol. Methods: One hundred women were randomized by computer to receive either OC pills or placebo, immediately after medical abortion. Results: There was no difference in the complete abortion rate between the two groups. The complete abortion rate was 98 and 92% in the OC and placebo groups respectively. The side-effects and duration of bleeding were also similar. The median days of vaginal bleeding were 17 (range: 3-41) and 15 (range: 5-48) in the OC and placebo groups respectively. There was a statistically significant decrease in the mean haemoglobin level on day 15 in the OC group (from 12.0 to 11.5 g/dl) whereas the mean haemoglobin level in the placebo group remained stable. The median measured blood loss was 69.9 ml in the OC group and 72.8 ml in the placebo group and there was no statistically significant difference between the two groups. Conclusion: We conclude that it is safe to offer women combined OC pills immediately after medical abortion as an option of contraception, as it does not affect the duration or amount of vaginal bleeding or the complete abortion rate.
Persistent Identifierhttp://hdl.handle.net/10722/87320
ISSN
2015 Impact Factor: 4.621
2015 SCImago Journal Rankings: 2.271
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTang, OSen_HK
dc.contributor.authorXu, Jen_HK
dc.contributor.authorCheng, Len_HK
dc.contributor.authorLee, SWHen_HK
dc.contributor.authorHo, PCen_HK
dc.date.accessioned2010-09-06T09:28:09Z-
dc.date.available2010-09-06T09:28:09Z-
dc.date.issued2002en_HK
dc.identifier.citationHuman Reproduction, 2002, v. 17 n. 1, p. 99-102en_HK
dc.identifier.issn0268-1161en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87320-
dc.description.abstractBackground: A prospective randomized placebo controlled trial was performed to assess the immediate use of oral contraceptive (OC) on the amount of blood loss in the post-abortion period in women undergoing medical abortion by mifepristone and misoprostol. Methods: One hundred women were randomized by computer to receive either OC pills or placebo, immediately after medical abortion. Results: There was no difference in the complete abortion rate between the two groups. The complete abortion rate was 98 and 92% in the OC and placebo groups respectively. The side-effects and duration of bleeding were also similar. The median days of vaginal bleeding were 17 (range: 3-41) and 15 (range: 5-48) in the OC and placebo groups respectively. There was a statistically significant decrease in the mean haemoglobin level on day 15 in the OC group (from 12.0 to 11.5 g/dl) whereas the mean haemoglobin level in the placebo group remained stable. The median measured blood loss was 69.9 ml in the OC group and 72.8 ml in the placebo group and there was no statistically significant difference between the two groups. Conclusion: We conclude that it is safe to offer women combined OC pills immediately after medical abortion as an option of contraception, as it does not affect the duration or amount of vaginal bleeding or the complete abortion rate.en_HK
dc.languageengen_HK
dc.publisherOxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/en_HK
dc.relation.ispartofHuman Reproductionen_HK
dc.rightsHuman Reproduction. Copyright © Oxford University Press.en_HK
dc.subjectMeasured blood lossen_HK
dc.subjectMifepristoneen_HK
dc.subjectMisoprostolen_HK
dc.subjectOC pillsen_HK
dc.titleThe effect of contraceptive pills on the measured blood loss in medical termination of pregnancy by mifepristone and misoprostol: A randomized placebo controlled trialen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0268-1161&volume=17&issue=1&spage=99&epage=102&date=2002&atitle=The+effect+of+contraceptive+pills+on+the+measured+blood+loss+in+medical+termination+of+pregnancy+by+mifepristone+and+misoprostol:+a+randomized+placebo+controlled+trialen_HK
dc.identifier.emailHo, PC:pcho@hku.hken_HK
dc.identifier.authorityHo, PC=rp00325en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid11756369-
dc.identifier.scopuseid_2-s2.0-0036161263en_HK
dc.identifier.hkuros65423en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036161263&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume17en_HK
dc.identifier.issue1en_HK
dc.identifier.spage99en_HK
dc.identifier.epage102en_HK
dc.identifier.isiWOS:000173395300019-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridTang, OS=7006723402en_HK
dc.identifier.scopusauthoridXu, J=7407007994en_HK
dc.identifier.scopusauthoridCheng, L=34869443100en_HK
dc.identifier.scopusauthoridLee, SWH=26030998000en_HK
dc.identifier.scopusauthoridHo, PC=7402211440en_HK

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