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Article: Prostaglandins for induction of second-trimester termination and intrauterine death

TitleProstaglandins for induction of second-trimester termination and intrauterine death
Authors
KeywordsIntrauterine death
Prostaglandin
Second-trimester abortion
Issue Date2003
PublisherBailliere Tindall. The Journal's web site is located at http://www.elsevier.com/locate/bpobgyn
Citation
Best Practice And Research: Clinical Obstetrics And Gynaecology, 2003, v. 17 n. 5, p. 765-775 How to Cite?
AbstractThe introduction of synthetic prostaglandin has revolutionized the treatment protocol for induction of second-trimester abortion and intrauterine death. Gemeprost is the only licensed synthetic prostaglandin analogue for second-trimester abortion in the United Kingdom. However, it is expensive and needs to be stored in a refrigerator. Misoprostol is marketed for use in the prevention and treatment of peptic ulcer. It is inexpensive and can be stored at room temperature. It has been widely used for induction of second-trimester abortion and intrauterine death. Misoprostol, 400 μg given vaginally every 3 hours, is probably the optimal regimen for second-trimester abortion. The combination of misoprostol and mifepristone significantly reduced the induction-to-abortion interval when compared with the misoprostol-only regimen. In addition, misoprostol can also be used as a cervical priming agent prior to dilatation and evacuation in second-trimester abortion.
Persistent Identifierhttp://hdl.handle.net/10722/87164
ISSN
2015 Impact Factor: 2.291
2015 SCImago Journal Rankings: 1.123
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNgai, SWen_HK
dc.contributor.authorTang, OSen_HK
dc.contributor.authorHo, PCen_HK
dc.date.accessioned2010-09-06T09:26:09Z-
dc.date.available2010-09-06T09:26:09Z-
dc.date.issued2003en_HK
dc.identifier.citationBest Practice And Research: Clinical Obstetrics And Gynaecology, 2003, v. 17 n. 5, p. 765-775en_HK
dc.identifier.issn1521-6934en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87164-
dc.description.abstractThe introduction of synthetic prostaglandin has revolutionized the treatment protocol for induction of second-trimester abortion and intrauterine death. Gemeprost is the only licensed synthetic prostaglandin analogue for second-trimester abortion in the United Kingdom. However, it is expensive and needs to be stored in a refrigerator. Misoprostol is marketed for use in the prevention and treatment of peptic ulcer. It is inexpensive and can be stored at room temperature. It has been widely used for induction of second-trimester abortion and intrauterine death. Misoprostol, 400 μg given vaginally every 3 hours, is probably the optimal regimen for second-trimester abortion. The combination of misoprostol and mifepristone significantly reduced the induction-to-abortion interval when compared with the misoprostol-only regimen. In addition, misoprostol can also be used as a cervical priming agent prior to dilatation and evacuation in second-trimester abortion.en_HK
dc.languageengen_HK
dc.publisherBailliere Tindall. The Journal's web site is located at http://www.elsevier.com/locate/bpobgynen_HK
dc.relation.ispartofBest Practice and Research: Clinical Obstetrics and Gynaecologyen_HK
dc.subjectIntrauterine deathen_HK
dc.subjectProstaglandinen_HK
dc.subjectSecond-trimester abortionen_HK
dc.titleProstaglandins for induction of second-trimester termination and intrauterine deathen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1521-6934&volume=17&issue=5&spage=765&epage=775&date=2003&atitle=Prostaglandins+for+induction+of+second-trimester+termination+and+intrauterine+deathen_HK
dc.identifier.emailHo, PC:pcho@hku.hken_HK
dc.identifier.authorityHo, PC=rp00325en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S1521-6934(03)00068-3en_HK
dc.identifier.pmid12972013-
dc.identifier.scopuseid_2-s2.0-0141830265en_HK
dc.identifier.hkuros87477en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0141830265&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume17en_HK
dc.identifier.issue5en_HK
dc.identifier.spage765en_HK
dc.identifier.epage775en_HK
dc.identifier.isiWOS:000185671700007-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridNgai, SW=7006074214en_HK
dc.identifier.scopusauthoridTang, OS=7006723402en_HK
dc.identifier.scopusauthoridHo, PC=7402211440en_HK

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