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Article: Spontaneous growth in Chinese patients with Turner's syndrome and influence of karyotype

TitleSpontaneous growth in Chinese patients with Turner's syndrome and influence of karyotype
Authors
KeywordsChinese
growth curve
karyotype
Turner's syndrome
Issue Date1997
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journal.asp?ref=1328-8067&site=1
Citation
Acta Paediatrica, International Journal Of Paediatrics, 1997, v. 86 n. 1, p. 18-21 How to Cite?
AbstractThe pretreatment mixed cross-sectional and longitudinal height measurements of 203 patients with Turner's syndrome (TS) were analysed. Only one observation was included per year per child and a total of 858 observations formed the basis of the growth study. The mean and SD values were fitted separately by a second-degree polynomial function, giving smoothed growth curves. The spontaneous growth pattern of Chinese girls with TS runs parallel to published Caucasian TS growth curves. The mean final height of Chinese patients with TS was 142 cm compared to 147 cm and 139 cm observed in Northern European and Japanese patients, respectively. Patients with the 46,X,i(Xq) karyotype were found to be significantly shorter, whereas children with the 45,X/46,XY and 46,X,del(Xq) karyotypes were significantly taller among this group of patients. Patients with TS who were disomic for Xp are significantly taller than patients who were monosomic for Xp. Our results suggest that karyotype can have a significant effect on the growth of children with TS.
Persistent Identifierhttp://hdl.handle.net/10722/87018
ISSN
2015 Impact Factor: 1.647
2015 SCImago Journal Rankings: 0.794
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLow, LCKen_HK
dc.contributor.authorSham, Cen_HK
dc.contributor.authorKwan, Een_HK
dc.contributor.authorKarlberg, Jen_HK
dc.contributor.authorTang, Gen_HK
dc.contributor.authorCheung, PTen_HK
dc.contributor.authorPang, Hen_HK
dc.contributor.authorTse, Wen_HK
dc.contributor.authorBut, Ben_HK
dc.contributor.authorYu, CMen_HK
dc.contributor.authorLam, STSen_HK
dc.date.accessioned2010-09-06T09:24:14Z-
dc.date.available2010-09-06T09:24:14Z-
dc.date.issued1997en_HK
dc.identifier.citationActa Paediatrica, International Journal Of Paediatrics, 1997, v. 86 n. 1, p. 18-21en_HK
dc.identifier.issn0803-5253en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87018-
dc.description.abstractThe pretreatment mixed cross-sectional and longitudinal height measurements of 203 patients with Turner's syndrome (TS) were analysed. Only one observation was included per year per child and a total of 858 observations formed the basis of the growth study. The mean and SD values were fitted separately by a second-degree polynomial function, giving smoothed growth curves. The spontaneous growth pattern of Chinese girls with TS runs parallel to published Caucasian TS growth curves. The mean final height of Chinese patients with TS was 142 cm compared to 147 cm and 139 cm observed in Northern European and Japanese patients, respectively. Patients with the 46,X,i(Xq) karyotype were found to be significantly shorter, whereas children with the 45,X/46,XY and 46,X,del(Xq) karyotypes were significantly taller among this group of patients. Patients with TS who were disomic for Xp are significantly taller than patients who were monosomic for Xp. Our results suggest that karyotype can have a significant effect on the growth of children with TS.en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journal.asp?ref=1328-8067&site=1en_HK
dc.relation.ispartofActa Paediatrica, International Journal of Paediatricsen_HK
dc.subjectChineseen_HK
dc.subjectgrowth curveen_HK
dc.subjectkaryotypeen_HK
dc.subjectTurner's syndromeen_HK
dc.titleSpontaneous growth in Chinese patients with Turner's syndrome and influence of karyotypeen_HK
dc.typeArticleen_HK
dc.identifier.emailLow, LCK: lcklow@hkucc.hku.hken_HK
dc.identifier.emailKarlberg, J: jpekarl@hkucc.hku.hken_HK
dc.identifier.emailTang, G: gwktang@hkucc.hku.hken_HK
dc.identifier.emailCheung, PT: ptcheung@hku.hken_HK
dc.identifier.authorityLow, LCK=rp00337en_HK
dc.identifier.authorityKarlberg, J=rp00400en_HK
dc.identifier.authorityTang, G=rp00328en_HK
dc.identifier.authorityCheung, PT=rp00351en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid9116419-
dc.identifier.scopuseid_2-s2.0-8044219685en_HK
dc.identifier.hkuros32988en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-8044219685&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume86en_HK
dc.identifier.issue1en_HK
dc.identifier.spage18en_HK
dc.identifier.epage21en_HK
dc.identifier.isiWOS:A1997WF14600004-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridLow, LCK=7007049461en_HK
dc.identifier.scopusauthoridSham, C=36787264300en_HK
dc.identifier.scopusauthoridKwan, E=55222528300en_HK
dc.identifier.scopusauthoridKarlberg, J=7005218406en_HK
dc.identifier.scopusauthoridTang, G=7401633864en_HK
dc.identifier.scopusauthoridCheung, PT=7202595465en_HK
dc.identifier.scopusauthoridPang, H=16948684600en_HK
dc.identifier.scopusauthoridTse, W=7006289004en_HK
dc.identifier.scopusauthoridBut, B=16945870900en_HK
dc.identifier.scopusauthoridYu, CM=15758569300en_HK
dc.identifier.scopusauthoridLam, STS=7402279428en_HK

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