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Article: Bone turnover in young hypoestrogenic women on hormonal therapy

TitleBone turnover in young hypoestrogenic women on hormonal therapy
Authors
KeywordsBiochemical markers
Bone turnover
Hormonal therapy
Hypoestrogenism
Young women
Issue Date2006
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ejogrb
Citation
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2006, v. 124 n. 2, p. 204-206 How to Cite?
AbstractObjective: To compare the biochemical markers of bone turnover in hypoestrogenic women who had been on the standard dosage of Premarin® 0.625 mg to that of the age-matched women who were menstruating spontaneously. Study design: Chinese women between 25 and 40 years of age with a diagnosis of hypoestrogenism who had been on Premarin® 0.625 mg daily for more than 1 year were recruited. The control group comprised age- and parity-matched women who had proven ovulation by mid-cycle serum luiteinising hormone surge. Serum osteocalcin and serum pyridinoline crosslink, markers of bone formation and resorption, respectively, were measured by enzyme-linked immunosorbent assays. Results: Twenty hypoestrogenic Chinese patients with a mean age of 36.2 were recruited as the study group. The same number of controls was recruited. There were no smokers in either group. The body weight, body height and body mass indices were comparable between the two groups. Both biochemical markers of bone metabolism did not differ between the two groups. Conclusion: The average bone turn-over rate in young hypoestrogenic Chinese women on Premarin® 0.625 mg/day was similar to that of normal menstruating women. © 2005 Elsevier Ireland Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/87011
ISSN
2015 Impact Factor: 1.662
2015 SCImago Journal Rankings: 0.808
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, CCWen_HK
dc.contributor.authorTang, OSen_HK
dc.contributor.authorLau, WNTen_HK
dc.contributor.authorTang, GWKen_HK
dc.date.accessioned2010-09-06T09:24:09Z-
dc.date.available2010-09-06T09:24:09Z-
dc.date.issued2006en_HK
dc.identifier.citationEuropean Journal of Obstetrics & Gynecology and Reproductive Biology, 2006, v. 124 n. 2, p. 204-206en_HK
dc.identifier.issn0301-2115en_HK
dc.identifier.urihttp://hdl.handle.net/10722/87011-
dc.description.abstractObjective: To compare the biochemical markers of bone turnover in hypoestrogenic women who had been on the standard dosage of Premarin® 0.625 mg to that of the age-matched women who were menstruating spontaneously. Study design: Chinese women between 25 and 40 years of age with a diagnosis of hypoestrogenism who had been on Premarin® 0.625 mg daily for more than 1 year were recruited. The control group comprised age- and parity-matched women who had proven ovulation by mid-cycle serum luiteinising hormone surge. Serum osteocalcin and serum pyridinoline crosslink, markers of bone formation and resorption, respectively, were measured by enzyme-linked immunosorbent assays. Results: Twenty hypoestrogenic Chinese patients with a mean age of 36.2 were recruited as the study group. The same number of controls was recruited. There were no smokers in either group. The body weight, body height and body mass indices were comparable between the two groups. Both biochemical markers of bone metabolism did not differ between the two groups. Conclusion: The average bone turn-over rate in young hypoestrogenic Chinese women on Premarin® 0.625 mg/day was similar to that of normal menstruating women. © 2005 Elsevier Ireland Ltd. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ejogrben_HK
dc.relation.ispartofEuropean Journal of Obstetrics & Gynecology and Reproductive Biologyen_HK
dc.rightsEuropean Journal of Obstetrics & Gynecology and Reproductive Biology. Copyright © Elsevier Ireland Ltd.en_HK
dc.subjectBiochemical markersen_HK
dc.subjectBone turnoveren_HK
dc.subjectHormonal therapyen_HK
dc.subjectHypoestrogenismen_HK
dc.subjectYoung womenen_HK
dc.titleBone turnover in young hypoestrogenic women on hormonal therapyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0301-2115&volume=124&spage=204&epage=206&date=2006&atitle=Bone+turnover+in+young+hypoestrogenic+women+on+hormonal+therapyen_HK
dc.identifier.emailTang, GWK:gwktang@hkucc.hku.hken_HK
dc.identifier.authorityTang, GWK=rp00328en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.ejogrb.2005.07.010en_HK
dc.identifier.pmid16112793-
dc.identifier.scopuseid_2-s2.0-31344456998en_HK
dc.identifier.hkuros117213en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-31344456998&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume124en_HK
dc.identifier.issue2en_HK
dc.identifier.spage204en_HK
dc.identifier.epage206en_HK
dc.identifier.isiWOS:000235348200014-
dc.publisher.placeIrelanden_HK
dc.identifier.scopusauthoridChan, CCW=26643394500en_HK
dc.identifier.scopusauthoridTang, OS=36881248500en_HK
dc.identifier.scopusauthoridLau, WNT=36847553600en_HK
dc.identifier.scopusauthoridTang, GWK=7401633864en_HK

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