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Article: Passive smoking exposure and risk of COPD among adults in China: the Guangzhou Biobank Cohort Study

TitlePassive smoking exposure and risk of COPD among adults in China: the Guangzhou Biobank Cohort Study
Authors
Issue Date2007
PublisherThe Lancet Publishing Group. The Journal's web site is located at http://www.elsevier.com/locate/lancet
Citation
Lancet, 2007, v. 370 n. 9589, p. 751-757 How to Cite?
AbstractBackground: Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality in China, where the population is also exposed to high levels of passive smoking, yet little information exists on the effects of such exposure on COPD. We examined the relation between passive smoking and COPD and respiratory symptoms in an adult Chinese population. Methods: We used baseline data from the Guangzhou Biobank Cohort Study. Of 20 430 men and women over the age of 50 recruited in 2003-06, 15 379 never smokers (6497 with valid spirometry) were included in this cross-sectional analysis. We measured passive smoking exposure at home and work by two self-reported measures (density and duration of exposure). Diagnosis of COPD was based on spirometry and defined according to the GOLD guidelines. Findings: There was an association between risk of COPD and self-reported exposure to passive smoking at home and work (adjusted odds ratio 1·48, 95% CI 1·18-1·85 for high level exposure; equivalent to 40 h a week for more than 5 years). There were significant associations between reported respiratory symptoms and increasing passive smoking exposure (1·16, 1·07-1·25 for any symptom). Interpretation: Exposure to passive smoking is associated with an increased prevalence of COPD and respiratory symptoms. If this association is causal, we estimate that 1·9 million excess deaths from COPD among never smokers could be attributable to passive smoking in the current population in China. Our findings provide strong evidence for urgent measures against passive smoking in China. © 2007 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/86912
ISSN
2015 Impact Factor: 44.002
2015 SCImago Journal Rankings: 14.638
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYin, Pen_HK
dc.contributor.authorJiang, Cen_HK
dc.contributor.authorCheng, Ken_HK
dc.contributor.authorLam, Ten_HK
dc.contributor.authorLam, Ken_HK
dc.contributor.authorMiller, Men_HK
dc.contributor.authorZhang, Wen_HK
dc.contributor.authorThomas, Gen_HK
dc.contributor.authorAdab, Pen_HK
dc.date.accessioned2010-09-06T09:22:51Z-
dc.date.available2010-09-06T09:22:51Z-
dc.date.issued2007en_HK
dc.identifier.citationLancet, 2007, v. 370 n. 9589, p. 751-757en_HK
dc.identifier.issn0140-6736en_HK
dc.identifier.urihttp://hdl.handle.net/10722/86912-
dc.description.abstractBackground: Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality in China, where the population is also exposed to high levels of passive smoking, yet little information exists on the effects of such exposure on COPD. We examined the relation between passive smoking and COPD and respiratory symptoms in an adult Chinese population. Methods: We used baseline data from the Guangzhou Biobank Cohort Study. Of 20 430 men and women over the age of 50 recruited in 2003-06, 15 379 never smokers (6497 with valid spirometry) were included in this cross-sectional analysis. We measured passive smoking exposure at home and work by two self-reported measures (density and duration of exposure). Diagnosis of COPD was based on spirometry and defined according to the GOLD guidelines. Findings: There was an association between risk of COPD and self-reported exposure to passive smoking at home and work (adjusted odds ratio 1·48, 95% CI 1·18-1·85 for high level exposure; equivalent to 40 h a week for more than 5 years). There were significant associations between reported respiratory symptoms and increasing passive smoking exposure (1·16, 1·07-1·25 for any symptom). Interpretation: Exposure to passive smoking is associated with an increased prevalence of COPD and respiratory symptoms. If this association is causal, we estimate that 1·9 million excess deaths from COPD among never smokers could be attributable to passive smoking in the current population in China. Our findings provide strong evidence for urgent measures against passive smoking in China. © 2007 Elsevier Ltd. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherThe Lancet Publishing Group. The Journal's web site is located at http://www.elsevier.com/locate/lanceten_HK
dc.relation.ispartofLanceten_HK
dc.subject.meshAgeden_HK
dc.subject.meshAged, 80 and overen_HK
dc.subject.meshChina - epidemiologyen_HK
dc.subject.meshCohort Studiesen_HK
dc.subject.meshEnvironmental Exposure - adverse effectsen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshOccupational Exposure - adverse effectsen_HK
dc.subject.meshPrevalenceen_HK
dc.subject.meshPulmonary Disease, Chronic Obstructive - diagnosis - epidemiology - etiologyen_HK
dc.subject.meshQuestionnairesen_HK
dc.subject.meshSocial Classen_HK
dc.subject.meshSpirometryen_HK
dc.subject.meshTobacco Smoke Pollution - adverse effectsen_HK
dc.titlePassive smoking exposure and risk of COPD among adults in China: the Guangzhou Biobank Cohort Studyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0140-6736&volume=370&spage=751&epage=757&date=2007&atitle=Passive+smoking+exposure+and+risk+of+COPD+among+adults+in+China:+The+Guangzhou+Biobank+Cohort+Studyen_HK
dc.identifier.emailLam, T:hrmrlth@hkucc.hku.hken_HK
dc.identifier.authorityLam, T=rp00326en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0140-6736(07)61378-6en_HK
dc.identifier.pmid17765524-
dc.identifier.scopuseid_2-s2.0-34548220492en_HK
dc.identifier.hkuros134502en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34548220492&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume370en_HK
dc.identifier.issue9589en_HK
dc.identifier.spage751en_HK
dc.identifier.epage757en_HK
dc.identifier.isiWOS:000249209300029-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridYin, P=14623527300en_HK
dc.identifier.scopusauthoridJiang, C=37044008400en_HK
dc.identifier.scopusauthoridCheng, K=36986607900en_HK
dc.identifier.scopusauthoridLam, T=7202522876en_HK
dc.identifier.scopusauthoridLam, K=20433798600en_HK
dc.identifier.scopusauthoridMiller, M=20434236900en_HK
dc.identifier.scopusauthoridZhang, W=20434989700en_HK
dc.identifier.scopusauthoridThomas, G=35465269900en_HK
dc.identifier.scopusauthoridAdab, P=6601949045en_HK

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