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Article: Fibrinogen, angina and coronary heart disease in a Chinese population

TitleFibrinogen, angina and coronary heart disease in a Chinese population
Authors
Issue Date2000
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/atherosclerosis
Citation
Atherosclerosis, 2000, v. 149 n. 2, p. 443-449 How to Cite?
AbstractAlthough fibrinogen is an established risk factor of coronary heart disease (CHD), whether fibrinogen is associated with CHD in Chinese is not clear. This population-based cross-sectional study aimed to analyse this relationship in Hong Kong Chinese. Fibrinogen was measured by the Clauss method in 1348 men and 1385 women aged 25-74 years. Severity of CHD was defined as most serious if the subjects had medically diagnosed CHD, as less serious if they had angina only, and as normal if they had neither. The prevalence of angina and CHD was respectively 2.4% and 2.2% in men and 3.2% and 2.7% in women. In men the age-adjusted mean fibrinogen concentration was 2.47 (95% confidence interval (CI) 2.43-2.51) g/l in the normal group, 2.65 (95% CI 2.45-2.85) g/l in the angina group, and 2.78 (95% CI 2.56-3.00) g/l in the CHD cases (P<0.01); in women it was respectively 2.61 (95% CI 2.59-2.63), 2.66 (95% CI 2.50-2.82), 2.90 (95% CI 2.72-3.08) g/l (P<0.01). The differences were significant after adjustment of other significant risk factors. We conclude that fibrinogen should be considered as a risk factor in Chinese. Copyright (C) 2000 Elsevier Science Ireland Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/86906
ISSN
2015 Impact Factor: 3.942
2015 SCImago Journal Rankings: 1.819
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLam, THen_HK
dc.contributor.authorLiu, LJen_HK
dc.contributor.authorJanus, EDen_HK
dc.contributor.authorLau, CPen_HK
dc.contributor.authorHedley, AJen_HK
dc.date.accessioned2010-09-06T09:22:47Z-
dc.date.available2010-09-06T09:22:47Z-
dc.date.issued2000en_HK
dc.identifier.citationAtherosclerosis, 2000, v. 149 n. 2, p. 443-449en_HK
dc.identifier.issn0021-9150en_HK
dc.identifier.urihttp://hdl.handle.net/10722/86906-
dc.description.abstractAlthough fibrinogen is an established risk factor of coronary heart disease (CHD), whether fibrinogen is associated with CHD in Chinese is not clear. This population-based cross-sectional study aimed to analyse this relationship in Hong Kong Chinese. Fibrinogen was measured by the Clauss method in 1348 men and 1385 women aged 25-74 years. Severity of CHD was defined as most serious if the subjects had medically diagnosed CHD, as less serious if they had angina only, and as normal if they had neither. The prevalence of angina and CHD was respectively 2.4% and 2.2% in men and 3.2% and 2.7% in women. In men the age-adjusted mean fibrinogen concentration was 2.47 (95% confidence interval (CI) 2.43-2.51) g/l in the normal group, 2.65 (95% CI 2.45-2.85) g/l in the angina group, and 2.78 (95% CI 2.56-3.00) g/l in the CHD cases (P<0.01); in women it was respectively 2.61 (95% CI 2.59-2.63), 2.66 (95% CI 2.50-2.82), 2.90 (95% CI 2.72-3.08) g/l (P<0.01). The differences were significant after adjustment of other significant risk factors. We conclude that fibrinogen should be considered as a risk factor in Chinese. Copyright (C) 2000 Elsevier Science Ireland Ltd.en_HK
dc.languageengen_HK
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/atherosclerosisen_HK
dc.relation.ispartofAtherosclerosisen_HK
dc.rightsAtherosclerosis. Copyright © Elsevier Ireland Ltd.en_HK
dc.subject.meshAdulten_HK
dc.subject.meshAge Distributionen_HK
dc.subject.meshAgeden_HK
dc.subject.meshAgingen_HK
dc.subject.meshAnalysis of Varianceen_HK
dc.subject.meshAngina Pectoris - diagnosis - epidemiologyen_HK
dc.subject.meshAsian Continental Ancestry Group - geneticsen_HK
dc.subject.meshChina - ethnologyen_HK
dc.subject.meshCoronary Disease - diagnosis - epidemiologyen_HK
dc.subject.meshCross-Sectional Studiesen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshFibrinogen - analysis - metabolismen_HK
dc.subject.meshHong Kong - epidemiologyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshIncidenceen_HK
dc.subject.meshLinear Modelsen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshMultivariate Analysisen_HK
dc.subject.meshPopulation Surveillanceen_HK
dc.subject.meshRisk Factorsen_HK
dc.subject.meshSex Distributionen_HK
dc.subject.meshSurvival Rateen_HK
dc.titleFibrinogen, angina and coronary heart disease in a Chinese populationen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0021-9150&volume=149&spage=443&epage=449&date=2000&atitle=Fibrinogen,+angina+and+coronary+heart+disease+in+a+Chinese+populationen_HK
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_HK
dc.identifier.emailHedley, AJ:hrmrajh@hkucc.hku.hken_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.identifier.authorityHedley, AJ=rp00357en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0021-9150(99)00347-0en_HK
dc.identifier.pmid10729396-
dc.identifier.scopuseid_2-s2.0-0034062153en_HK
dc.identifier.hkuros48417en_HK
dc.identifier.hkuros57056-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034062153&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume149en_HK
dc.identifier.issue2en_HK
dc.identifier.spage443en_HK
dc.identifier.epage449en_HK
dc.identifier.isiWOS:000086344900022-
dc.publisher.placeIrelanden_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK
dc.identifier.scopusauthoridLiu, LJ=21737444900en_HK
dc.identifier.scopusauthoridJanus, ED=7006936536en_HK
dc.identifier.scopusauthoridLau, CP=7401968501en_HK
dc.identifier.scopusauthoridHedley, AJ=7102584095en_HK

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