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Article: Implications of increased weight and waist circumference on vascular risk in an older Chinese population: The Guangzhou Biobank Cohort Study

TitleImplications of increased weight and waist circumference on vascular risk in an older Chinese population: The Guangzhou Biobank Cohort Study
Authors
Issue Date2008
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/atherosclerosis
Citation
Atherosclerosis, 2008, v. 196 n. 2, p. 682-688 How to Cite?
AbstractBackground: The relationships between weight and waist on vascular risk are well described, but the long-term impact of these parameters is less clearly defined, particularly in Chinese populations. Methods: Ten thousand four hundred and ten older subjects (50-85 years) were recruited and blood pressure, anthropometric, and fasting vascular risk factors measured. Socioeconomic and demographic data, including self-reported weight and waist gain since 18 years. The association of weight and waist gain with these vascular risk factors was analysed. Results: Weight, and particularly waist gain were associated with a more adverse vascular risk factor profile, with the most adverse profile associated with gains in both weight and waist. Anthropometric gains were associated with increased risk even in non-obese subjects (p < 0.05). Even after adjustment for a range of demographic and socioeconomic factors, waist gain was associated with additional risk of having the metabolic syndrome and its components and self-reported vascular disease in those centrally obese subjects (p < 0.05 for all). Conclusion: Increased weight and waist increased the level of vascular risk factors and self-reported disease in both non-obese and obese subjects. The high prevalence of vascular risk factors in this population forewarns of a major developing health burden in the rapidly modernising 1.2 billion Chinese population. © 2007 Elsevier Ireland Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/86831
ISSN
2015 Impact Factor: 3.942
2015 SCImago Journal Rankings: 1.819
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorThomas, GNen_HK
dc.contributor.authorLao, XQen_HK
dc.contributor.authorJiang, CQen_HK
dc.contributor.authorMcGhee, SMen_HK
dc.contributor.authorZhang, WSen_HK
dc.contributor.authorAdab, Pen_HK
dc.contributor.authorLam, THen_HK
dc.contributor.authorCheng, KKen_HK
dc.date.accessioned2010-09-06T09:21:51Z-
dc.date.available2010-09-06T09:21:51Z-
dc.date.issued2008en_HK
dc.identifier.citationAtherosclerosis, 2008, v. 196 n. 2, p. 682-688en_HK
dc.identifier.issn0021-9150en_HK
dc.identifier.urihttp://hdl.handle.net/10722/86831-
dc.description.abstractBackground: The relationships between weight and waist on vascular risk are well described, but the long-term impact of these parameters is less clearly defined, particularly in Chinese populations. Methods: Ten thousand four hundred and ten older subjects (50-85 years) were recruited and blood pressure, anthropometric, and fasting vascular risk factors measured. Socioeconomic and demographic data, including self-reported weight and waist gain since 18 years. The association of weight and waist gain with these vascular risk factors was analysed. Results: Weight, and particularly waist gain were associated with a more adverse vascular risk factor profile, with the most adverse profile associated with gains in both weight and waist. Anthropometric gains were associated with increased risk even in non-obese subjects (p < 0.05). Even after adjustment for a range of demographic and socioeconomic factors, waist gain was associated with additional risk of having the metabolic syndrome and its components and self-reported vascular disease in those centrally obese subjects (p < 0.05 for all). Conclusion: Increased weight and waist increased the level of vascular risk factors and self-reported disease in both non-obese and obese subjects. The high prevalence of vascular risk factors in this population forewarns of a major developing health burden in the rapidly modernising 1.2 billion Chinese population. © 2007 Elsevier Ireland Ltd. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/atherosclerosisen_HK
dc.relation.ispartofAtherosclerosisen_HK
dc.rightsAtherosclerosis. Copyright © Elsevier Ireland Ltd.en_HK
dc.subject.meshAgeden_HK
dc.subject.meshAged, 80 and overen_HK
dc.subject.meshAnthropometryen_HK
dc.subject.meshAsian Continental Ancestry Groupen_HK
dc.subject.meshBody Weighten_HK
dc.subject.meshChinaen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMetabolic Syndrome X - etiologyen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshObesity - complicationsen_HK
dc.subject.meshRisk Factorsen_HK
dc.subject.meshVascular Diseases - etiologyen_HK
dc.subject.meshWaist-Hip Ratioen_HK
dc.titleImplications of increased weight and waist circumference on vascular risk in an older Chinese population: The Guangzhou Biobank Cohort Studyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0021-9150&volume=196&issue=2&spage=682&epage=688&date=2008&atitle=Implications+of+increased+weight+and+waist+circumference+on+vascular+risk+in+an+older+Chinese+population:+The+Guangzhou+Biobank+Cohort+Studyen_HK
dc.identifier.emailMcGhee, SM:smmcghee@hkucc.hku.hken_HK
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_HK
dc.identifier.authorityMcGhee, SM=rp00393en_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.atherosclerosis.2007.07.024en_HK
dc.identifier.pmid17765903-
dc.identifier.scopuseid_2-s2.0-38649127908en_HK
dc.identifier.hkuros140364en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-38649127908&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume196en_HK
dc.identifier.issue2en_HK
dc.identifier.spage682en_HK
dc.identifier.epage688en_HK
dc.identifier.isiWOS:000253743800024-
dc.publisher.placeIrelanden_HK
dc.identifier.scopusauthoridThomas, GN=35465269900en_HK
dc.identifier.scopusauthoridLao, XQ=14031637000en_HK
dc.identifier.scopusauthoridJiang, CQ=10639500500en_HK
dc.identifier.scopusauthoridMcGhee, SM=7003288588en_HK
dc.identifier.scopusauthoridZhang, WS=13410704100en_HK
dc.identifier.scopusauthoridAdab, P=6601949045en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK
dc.identifier.scopusauthoridCheng, KK=7402997800en_HK

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