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Article: Demographic and lifestyle factors associated with dioxin-like activity (CALUX-TEQ) in human breast milk in Hong Kong

TitleDemographic and lifestyle factors associated with dioxin-like activity (CALUX-TEQ) in human breast milk in Hong Kong
Authors
Issue Date2006
PublisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/est
Citation
Environmental Science And Technology, 2006, v. 40 n. 5, p. 1432-1438 How to Cite?
AbstractMaternal exposure to dioxins and related compounds before conception may affect the health of the fetus. To identify factors affecting dioxin body load in Hong Kong, in 2002, total dioxin-like activity was estimated in 250 individual milk samples at 2-6 weeks postpartum, from a representative group of primiparous mothers, aged 18-42 years (mean 29 ± 5 years), by a chemically activated luciferase expression (CALUX) bioassay. Associations between the CALUX-TEQ and 20 socio-demographic and dietary variables were examined separately in mothers younger than 30 years (n = 114) and 30 years or older (n = 119), by multiple linear regression analysis. CALUX-TEQ (mean 14.5 ± 5.8 pg/g fat) significantly increased by 0.4-0.5 pg/g fat for every year of the mother's age. Mothers born in Guangdong province of China had a significantly higher CALUX-TEQ. Higher seafood consumption (older mothers; p = 0.07) and having a female baby (younger mothers; p = 0.002) were associated with a higher maternal CALUX-TEQ level. Age was the strongest factor affecting human dioxin levels in Hong Kong. Birthplace and residence are important indicators of variations in exposure to environmental pollution in the Asia Pacific region. Temporal trends in body loads of dioxins remain to be established and continuous monitoring of dioxins in humans and foods is necessary as a precautionary approach to guide environmental control measures and prevent exposure to infants. © 2006 American Chemical Society.
Persistent Identifierhttp://hdl.handle.net/10722/86699
ISSN
2015 Impact Factor: 5.393
2015 SCImago Journal Rankings: 2.664
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNelson, EASen_HK
dc.contributor.authorHui, LLen_HK
dc.contributor.authorWong, TWen_HK
dc.contributor.authorHedley, AJen_HK
dc.date.accessioned2010-09-06T09:20:15Z-
dc.date.available2010-09-06T09:20:15Z-
dc.date.issued2006en_HK
dc.identifier.citationEnvironmental Science And Technology, 2006, v. 40 n. 5, p. 1432-1438en_HK
dc.identifier.issn0013-936Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/86699-
dc.description.abstractMaternal exposure to dioxins and related compounds before conception may affect the health of the fetus. To identify factors affecting dioxin body load in Hong Kong, in 2002, total dioxin-like activity was estimated in 250 individual milk samples at 2-6 weeks postpartum, from a representative group of primiparous mothers, aged 18-42 years (mean 29 ± 5 years), by a chemically activated luciferase expression (CALUX) bioassay. Associations between the CALUX-TEQ and 20 socio-demographic and dietary variables were examined separately in mothers younger than 30 years (n = 114) and 30 years or older (n = 119), by multiple linear regression analysis. CALUX-TEQ (mean 14.5 ± 5.8 pg/g fat) significantly increased by 0.4-0.5 pg/g fat for every year of the mother's age. Mothers born in Guangdong province of China had a significantly higher CALUX-TEQ. Higher seafood consumption (older mothers; p = 0.07) and having a female baby (younger mothers; p = 0.002) were associated with a higher maternal CALUX-TEQ level. Age was the strongest factor affecting human dioxin levels in Hong Kong. Birthplace and residence are important indicators of variations in exposure to environmental pollution in the Asia Pacific region. Temporal trends in body loads of dioxins remain to be established and continuous monitoring of dioxins in humans and foods is necessary as a precautionary approach to guide environmental control measures and prevent exposure to infants. © 2006 American Chemical Society.en_HK
dc.languageengen_HK
dc.publisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/esten_HK
dc.relation.ispartofEnvironmental Science and Technologyen_HK
dc.subject.meshDemography-
dc.subject.meshDioxins - analysis - toxicity-
dc.subject.meshLife Style-
dc.subject.meshMilk, Human - chemistry-
dc.subject.meshPregnancy-
dc.titleDemographic and lifestyle factors associated with dioxin-like activity (CALUX-TEQ) in human breast milk in Hong Kongen_HK
dc.typeArticleen_HK
dc.identifier.emailHui, LL: huic@hkucc.hku.hken_HK
dc.identifier.emailHedley, AJ: hrmrajh@hkucc.hku.hken_HK
dc.identifier.authorityHui, LL=rp01698en_HK
dc.identifier.authorityHedley, AJ=rp00357en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1021/es052164ren_HK
dc.identifier.pmid16568753-
dc.identifier.scopuseid_2-s2.0-33644870298en_HK
dc.identifier.hkuros115917en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33644870298&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume40en_HK
dc.identifier.issue5en_HK
dc.identifier.spage1432en_HK
dc.identifier.epage1438en_HK
dc.identifier.isiWOS:000235796100016-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridNelson, EAS=7402264387en_HK
dc.identifier.scopusauthoridHui, LL=12774460100en_HK
dc.identifier.scopusauthoridWong, TW=7403531744en_HK
dc.identifier.scopusauthoridHedley, AJ=7102584095en_HK

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