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Article: Blood pressure indices and cardiovascular disease in the Asia Pacific Region: a pooled analysis

TitleBlood pressure indices and cardiovascular disease in the Asia Pacific Region: a pooled analysis
Authors
Issue Date2003
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.shef-ac-press.co.uk
Citation
Hypertension, 2003, v. 42 n. 1, p. 69-75 How to Cite?
Abstract
This article aims to compare the importance of systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), and pulse pressure (PP) as risk factors for stroke and ischemic heart disease and to assess whether the patterns are consistent by age and gender. Cox proportional-hazards regression, adjusted for cholesterol and smoking, was used to assess the associations of the 4 BP indices with stroke and ischemic heart disease by age and gender. The relative importance of individual indices was assessed with a hazard ratios for a 1-SD change in BP and by likelihood-ratio chi2 tests. The influence of >1 BP index in the Cox model was also estimated. The analyses demonstrated similar associations of SBP, DBP, and MAP with both fatal stroke and ischemic heart diseases, which were stronger than those of PP. Both SBP and MAP tended to be more important in the regression model than DBP or PP. In Cox models including DBP, addition of SBP improved the goodness of fit at all ages and for both genders. However, in Cox models including SBP, addition of DBP typically resulted in little incremental benefit over and above that of SBP alone. These data suggest that if time or resources are highly constrained, such as in much-needed epidemiologic surveys in developing countries, very little is lost from only measuring SBP.
Persistent Identifierhttp://hdl.handle.net/10722/86673
ISSN
2013 Impact Factor: 7.632
2013 SCImago Journal Rankings: 3.702
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLawes, CMMen_HK
dc.contributor.authorBennett, DAen_HK
dc.contributor.authorParag, Ven_HK
dc.contributor.authorWoodward, Men_HK
dc.contributor.authorWhitlock, Gen_HK
dc.contributor.authorLam, THen_HK
dc.contributor.authorSuh, Ien_HK
dc.contributor.authorRodgers, Aen_HK
dc.date.accessioned2010-09-06T09:19:55Z-
dc.date.available2010-09-06T09:19:55Z-
dc.date.issued2003en_HK
dc.identifier.citationHypertension, 2003, v. 42 n. 1, p. 69-75en_HK
dc.identifier.issn0194-911Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/86673-
dc.description.abstractThis article aims to compare the importance of systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), and pulse pressure (PP) as risk factors for stroke and ischemic heart disease and to assess whether the patterns are consistent by age and gender. Cox proportional-hazards regression, adjusted for cholesterol and smoking, was used to assess the associations of the 4 BP indices with stroke and ischemic heart disease by age and gender. The relative importance of individual indices was assessed with a hazard ratios for a 1-SD change in BP and by likelihood-ratio chi2 tests. The influence of >1 BP index in the Cox model was also estimated. The analyses demonstrated similar associations of SBP, DBP, and MAP with both fatal stroke and ischemic heart diseases, which were stronger than those of PP. Both SBP and MAP tended to be more important in the regression model than DBP or PP. In Cox models including DBP, addition of SBP improved the goodness of fit at all ages and for both genders. However, in Cox models including SBP, addition of DBP typically resulted in little incremental benefit over and above that of SBP alone. These data suggest that if time or resources are highly constrained, such as in much-needed epidemiologic surveys in developing countries, very little is lost from only measuring SBP.-
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.shef-ac-press.co.uken_HK
dc.relation.ispartofHypertensionen_HK
dc.subject.meshAge Factors-
dc.subject.meshBlood Pressure-
dc.subject.meshFar East - epidemiology-
dc.subject.meshMyocardial Ischemia - epidemiology - mortality-
dc.subject.meshStroke - epidemiology - mortality-
dc.titleBlood pressure indices and cardiovascular disease in the Asia Pacific Region: a pooled analysisen_HK
dc.typeArticleen_HK
dc.identifier.emailLam, TH: hrmrlth@hkucc.hku.hken_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1161/01.HYP.0000075083.04415.4B-
dc.identifier.pmid12756223-
dc.identifier.hkuros84399en_HK
dc.identifier.volume42-
dc.identifier.issue1-
dc.identifier.spage69-
dc.identifier.epage75-
dc.identifier.isiWOS:000183949900012-
dc.publisher.placeUnited States-

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