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Article: Cost-effectiveness of organized versus opportunistic cervical cytology screening in Hong Kong

TitleCost-effectiveness of organized versus opportunistic cervical cytology screening in Hong Kong
Authors
Issue Date2004
PublisherOxford University Press. The Journal's web site is located at http://jpubhealth.oxfordjournals.org/
Citation
Journal Of Public Health, 2004, v. 26 n. 2, p. 130-137 How to Cite?
AbstractBackground: To assess the cost-effectiveness of alternative cervical cancer screening strategies to inform the design and implementation of a government-sponsored population-based screening programme in Hong Kong. Methods: Cost-effectiveness analysis using a computer-based model of cervical carcinogenesis was performed. Strategies included no screening, opportunistic screening (status quo), organized screening using either conventional or liquid-based cytology conducted at different frequencies. The main outcome measures were cancer incidence reduction, years of life saved (YLS), lifetime costs and incremental cost-effectiveness ratios. Data were from local hospitals and laboratories, clinical trials, prospective studies and other published literature. Results: Compared with no screening, a simulation of the current situation of opportunistic screening using cervical cytology produced a nearly 40 per cent reduction in the lifetime risk of cervical cancer. However, with organized screening every 3, 4 and 5 years, corresponding reductions with conventional (and liquid-based) cytology were 90.4 (92.9), 86.8 (90.2) and 83.2 per cent (87.3 per cent) compared with no screening. For all cytology-based screening strategies, opportunistic screening was more costly and less effective than an organized programme of screening every 3, 4 and 5 years. Every 3-, 4- and 5-year screening cost $12 300, $7100 and $800 per YLS, each compared with the next best alternative. Conclusions: Compared with the status quo of opportunistic screening, adopting a policy of organized, mass cervical screening in Hong Kong can substantially increase benefits and reduce costs.
Persistent Identifierhttp://hdl.handle.net/10722/86644
ISSN
2015 Impact Factor: 2.019
2015 SCImago Journal Rankings: 0.933
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorKim, JJen_HK
dc.contributor.authorLeung, GMen_HK
dc.contributor.authorWoo, PPSen_HK
dc.contributor.authorGoldie, SJen_HK
dc.date.accessioned2010-09-06T09:19:34Z-
dc.date.available2010-09-06T09:19:34Z-
dc.date.issued2004en_HK
dc.identifier.citationJournal Of Public Health, 2004, v. 26 n. 2, p. 130-137en_HK
dc.identifier.issn1741-3842en_HK
dc.identifier.urihttp://hdl.handle.net/10722/86644-
dc.description.abstractBackground: To assess the cost-effectiveness of alternative cervical cancer screening strategies to inform the design and implementation of a government-sponsored population-based screening programme in Hong Kong. Methods: Cost-effectiveness analysis using a computer-based model of cervical carcinogenesis was performed. Strategies included no screening, opportunistic screening (status quo), organized screening using either conventional or liquid-based cytology conducted at different frequencies. The main outcome measures were cancer incidence reduction, years of life saved (YLS), lifetime costs and incremental cost-effectiveness ratios. Data were from local hospitals and laboratories, clinical trials, prospective studies and other published literature. Results: Compared with no screening, a simulation of the current situation of opportunistic screening using cervical cytology produced a nearly 40 per cent reduction in the lifetime risk of cervical cancer. However, with organized screening every 3, 4 and 5 years, corresponding reductions with conventional (and liquid-based) cytology were 90.4 (92.9), 86.8 (90.2) and 83.2 per cent (87.3 per cent) compared with no screening. For all cytology-based screening strategies, opportunistic screening was more costly and less effective than an organized programme of screening every 3, 4 and 5 years. Every 3-, 4- and 5-year screening cost $12 300, $7100 and $800 per YLS, each compared with the next best alternative. Conclusions: Compared with the status quo of opportunistic screening, adopting a policy of organized, mass cervical screening in Hong Kong can substantially increase benefits and reduce costs.en_HK
dc.languageengen_HK
dc.publisherOxford University Press. The Journal's web site is located at http://jpubhealth.oxfordjournals.org/en_HK
dc.relation.ispartofJournal of Public Healthen_HK
dc.rightsJournal of Public Health. Copyright © Oxford University Press.en_HK
dc.subject.meshActuarial Analysisen_HK
dc.subject.meshAdulten_HK
dc.subject.meshComputer Simulationen_HK
dc.subject.meshCost-Benefit Analysisen_HK
dc.subject.meshDiagnostic Tests, Routine - economics - utilizationen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHong Kong - epidemiologyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMarkov Chainsen_HK
dc.subject.meshMass Screening - economics - utilizationen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshQuality-Adjusted Life Yearsen_HK
dc.subject.meshTime Factorsen_HK
dc.subject.meshUterine Cervical Neoplasms - diagnosis - epidemiology - prevention & controlen_HK
dc.subject.meshVaginal Smears - economics - methods - utilizationen_HK
dc.titleCost-effectiveness of organized versus opportunistic cervical cytology screening in Hong Kongen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1741-3842&volume=26&spage=130&epage=137&date=2004&atitle=Cost-effectiveness+of+organized+versus+opportunistic+cervical+cytology+screening+in+Hong+Kongen_HK
dc.identifier.emailLeung, GM:gmleung@hku.hken_HK
dc.identifier.authorityLeung, GM=rp00460en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid15284314-
dc.identifier.scopuseid_2-s2.0-3543093258en_HK
dc.identifier.hkuros95647en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-3543093258&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume26en_HK
dc.identifier.issue2en_HK
dc.identifier.spage130en_HK
dc.identifier.epage137en_HK
dc.identifier.isiWOS:000223042300003-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridKim, JJ=16067004400en_HK
dc.identifier.scopusauthoridLeung, GM=7007159841en_HK
dc.identifier.scopusauthoridWoo, PPS=8426498200en_HK
dc.identifier.scopusauthoridGoldie, SJ=35427013900en_HK

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