File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Simulations of the HIV epidemic in sub-Saharan Africa: Sexual transmission versus transmission through unsafe medical injections

TitleSimulations of the HIV epidemic in sub-Saharan Africa: Sexual transmission versus transmission through unsafe medical injections
Authors
Issue Date2006
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.stdjournal.com
Citation
Sexually Transmitted Diseases, 2006, v. 33 n. 3, p. 127-134 How to Cite?
AbstractObjectives: Heterosexual transmission has long been considered the predominant route of transmission of HIV-1 in sub-Saharan Africa. However, some have argued that unsafe medical injections account for the majority of transmission in this region. Goal: The goal of this study was to compare the HIV-1 epidemics associated with different transmission routes. Study: An age-structured deterministic compartmental model of HIV-1 transmission through both sexual contact and unsafe injections was developed and simulations of sexual transmission and iatrogenic transmission were compared with observed prevalence. Results: Iatrogenic transmission probabilities and numbers of unsafe injections required to generate observed prevalence are unfeasibly high. Simulations of sexually transmitted HIV-1 generate observed prevalence using transmission probabilities and average partner change rates that are within plausible bounds. Conclusions: Heterosexual transmission seems a more likely route of transmission in the region. However, heterogeneity in contact patterns is of key importance. Further information on groups who are likely to receive more injections is required. Copyright © 2006, American Sexually Transmitted Diseases Association All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/86513
ISSN
2015 Impact Factor: 2.968
2015 SCImago Journal Rankings: 2.043
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorFrench, Ken_HK
dc.contributor.authorRiley, Sen_HK
dc.contributor.authorGarnett, Gen_HK
dc.date.accessioned2010-09-06T09:17:59Z-
dc.date.available2010-09-06T09:17:59Z-
dc.date.issued2006en_HK
dc.identifier.citationSexually Transmitted Diseases, 2006, v. 33 n. 3, p. 127-134en_HK
dc.identifier.issn0148-5717en_HK
dc.identifier.urihttp://hdl.handle.net/10722/86513-
dc.description.abstractObjectives: Heterosexual transmission has long been considered the predominant route of transmission of HIV-1 in sub-Saharan Africa. However, some have argued that unsafe medical injections account for the majority of transmission in this region. Goal: The goal of this study was to compare the HIV-1 epidemics associated with different transmission routes. Study: An age-structured deterministic compartmental model of HIV-1 transmission through both sexual contact and unsafe injections was developed and simulations of sexual transmission and iatrogenic transmission were compared with observed prevalence. Results: Iatrogenic transmission probabilities and numbers of unsafe injections required to generate observed prevalence are unfeasibly high. Simulations of sexually transmitted HIV-1 generate observed prevalence using transmission probabilities and average partner change rates that are within plausible bounds. Conclusions: Heterosexual transmission seems a more likely route of transmission in the region. However, heterogeneity in contact patterns is of key importance. Further information on groups who are likely to receive more injections is required. Copyright © 2006, American Sexually Transmitted Diseases Association All rights reserved.en_HK
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.stdjournal.comen_HK
dc.relation.ispartofSexually Transmitted Diseasesen_HK
dc.rightsSexually Transmitted Diseases. Copyright © Lippincott Williams & Wilkins.en_HK
dc.subject.meshAdolescenten_HK
dc.subject.meshAdulten_HK
dc.subject.meshAfrica South of the Sahara - epidemiologyen_HK
dc.subject.meshAgeden_HK
dc.subject.meshAged, 80 and overen_HK
dc.subject.meshChilden_HK
dc.subject.meshChild, Preschoolen_HK
dc.subject.meshDisease Outbreaksen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHIV Infections - epidemiology - transmission - virologyen_HK
dc.subject.meshHIV-1en_HK
dc.subject.meshHumansen_HK
dc.subject.meshIatrogenic Disease - epidemiologyen_HK
dc.subject.meshInfanten_HK
dc.subject.meshInfant, Newbornen_HK
dc.subject.meshInjections - adverse effectsen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshModels, Biologicalen_HK
dc.subject.meshPrevalenceen_HK
dc.subject.meshSexual Behavioren_HK
dc.titleSimulations of the HIV epidemic in sub-Saharan Africa: Sexual transmission versus transmission through unsafe medical injectionsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0148-5717&volume=33&spage=127&epage=134&date=2006&atitle=Simulations+of+the+HIV+epidemic+in+sub-Saharan+Africa:+Sexual+transmission+versus+transmission+through+unsafe+medical+injectionsen_HK
dc.identifier.emailRiley, S:sriley@hkucc.hku.hk, steven.riley@hku.hken_HK
dc.identifier.authorityRiley, S=rp00511en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/01.olq.0000204505.78077.e5en_HK
dc.identifier.pmid16508523-
dc.identifier.scopuseid_2-s2.0-33645968687en_HK
dc.identifier.hkuros115459en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33645968687&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume33en_HK
dc.identifier.issue3en_HK
dc.identifier.spage127en_HK
dc.identifier.epage134en_HK
dc.identifier.isiWOS:000235955300001-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridFrench, K=13005558500en_HK
dc.identifier.scopusauthoridRiley, S=7102619416en_HK
dc.identifier.scopusauthoridGarnett, G=7005464007en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats