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Article: A prospective population based study of gender differential in mortality from cardiovascular disease and 'all causes' in asymptomatic hyperglycaemics

TitleA prospective population based study of gender differential in mortality from cardiovascular disease and 'all causes' in asymptomatic hyperglycaemics
Authors
Issue Date1994
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/jclinepi
Citation
Journal Of Clinical Epidemiology, 1994, v. 47 n. 4, p. 397-405 How to Cite?
AbstractThere have been few prospective epidemiological studies of asymptomatic hyperglycaemia as a risk factor for cardiovascular disease and all causes mortality in women. Gender-specific all causes, cardiovascular disease (CVD), ischaemic heart disease (IHD) and stroke mortality rates and relative risks for asymptomatic hyperglycaemics (top 5%) have been compared to normoglycaemics (bottom 95%) during a mean follow-up of 11.6 years (range 10-14) among 4696 men and 5714 women aged 45-64 at entry in the west of Scotland. Univariate analysis showed that asymptomatic hyperglycaemia was associated with increased risk of all causes, CVD, IHD and stroke mortality in both genders. The degree of this association was greater in women than in men. Using multiple logistic regression (MLR) analysis to take into account differences in age, systolic (SBP) and diastolic blood pressure (DBP), serum cholesterol, body mass index (BMI), and cigarette smoking, high casual blood glucose level was still a significant risk factor for CVD mortality in both genders. It was also a significant risk factor for all causes, IHD and stroke mortality in women but not in men. This study shows that to a lesser degree asymptomatic hyperglycaemia shows the same gender differentials in risk of mortality as have been demonstrated amongst known diabetics.
Persistent Identifierhttp://hdl.handle.net/10722/86472
ISSN
2015 Impact Factor: 4.703
2015 SCImago Journal Rankings: 2.559
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorJanghorbani, Men_HK
dc.contributor.authorJones, RBen_HK
dc.contributor.authorGilmour, WHen_HK
dc.contributor.authorHedley, AJen_HK
dc.contributor.authorZhianpour, Men_HK
dc.date.accessioned2010-09-06T09:17:28Z-
dc.date.available2010-09-06T09:17:28Z-
dc.date.issued1994en_HK
dc.identifier.citationJournal Of Clinical Epidemiology, 1994, v. 47 n. 4, p. 397-405en_HK
dc.identifier.issn0895-4356en_HK
dc.identifier.urihttp://hdl.handle.net/10722/86472-
dc.description.abstractThere have been few prospective epidemiological studies of asymptomatic hyperglycaemia as a risk factor for cardiovascular disease and all causes mortality in women. Gender-specific all causes, cardiovascular disease (CVD), ischaemic heart disease (IHD) and stroke mortality rates and relative risks for asymptomatic hyperglycaemics (top 5%) have been compared to normoglycaemics (bottom 95%) during a mean follow-up of 11.6 years (range 10-14) among 4696 men and 5714 women aged 45-64 at entry in the west of Scotland. Univariate analysis showed that asymptomatic hyperglycaemia was associated with increased risk of all causes, CVD, IHD and stroke mortality in both genders. The degree of this association was greater in women than in men. Using multiple logistic regression (MLR) analysis to take into account differences in age, systolic (SBP) and diastolic blood pressure (DBP), serum cholesterol, body mass index (BMI), and cigarette smoking, high casual blood glucose level was still a significant risk factor for CVD mortality in both genders. It was also a significant risk factor for all causes, IHD and stroke mortality in women but not in men. This study shows that to a lesser degree asymptomatic hyperglycaemia shows the same gender differentials in risk of mortality as have been demonstrated amongst known diabetics.en_HK
dc.languageengen_HK
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/jclinepien_HK
dc.relation.ispartofJournal of Clinical Epidemiologyen_HK
dc.rightsJournal of Clinical Epidemiology. Copyright © Elsevier Inc.en_HK
dc.subject.meshCardiovascular Diseases - mortalityen_HK
dc.subject.meshCerebrovascular Disorders - mortalityen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshFollow-Up Studiesen_HK
dc.subject.meshHumansen_HK
dc.subject.meshHyperglycemia - complicationsen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshMyocardial Ischemia - mortalityen_HK
dc.subject.meshProspective Studiesen_HK
dc.subject.meshRegression Analysisen_HK
dc.subject.meshRisk Factorsen_HK
dc.subject.meshScotland - epidemiologyen_HK
dc.subject.meshSex Factorsen_HK
dc.titleA prospective population based study of gender differential in mortality from cardiovascular disease and 'all causes' in asymptomatic hyperglycaemicsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0895-4356&volume=47&spage=397&epage=405&date=1994&atitle=A+prospective+population+based+study+of+gender+differential+in+mortality+from+cardiovascular+disease+and+%27all+causes%27+in+asymptomatic+hyperglycaemicsen_HK
dc.identifier.emailHedley, AJ:hrmrajh@hkucc.hku.hken_HK
dc.identifier.authorityHedley, AJ=rp00357en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/0895-4356(94)90161-9en_HK
dc.identifier.pmid7730865-
dc.identifier.scopuseid_2-s2.0-0028269076en_HK
dc.identifier.hkuros1093en_HK
dc.identifier.volume47en_HK
dc.identifier.issue4en_HK
dc.identifier.spage397en_HK
dc.identifier.epage405en_HK
dc.identifier.isiWOS:A1994NG68500010-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridJanghorbani, M=7006225888en_HK
dc.identifier.scopusauthoridJones, RB=10042286500en_HK
dc.identifier.scopusauthoridGilmour, WH=7006492165en_HK
dc.identifier.scopusauthoridHedley, AJ=7102584095en_HK
dc.identifier.scopusauthoridZhianpour, M=7801563154en_HK

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