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Article: Triglyceride and coronary heart disease mortality in a 24-year follow-up study in Xi'an, China

TitleTriglyceride and coronary heart disease mortality in a 24-year follow-up study in Xi'an, China
Authors
Issue Date2004
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/annepidem
Citation
Annals Of Epidemiology, 2004, v. 14 n. 1, p. 1-7 How to Cite?
AbstractPURPOSE: To study whether serum triglyceride (TG) was associated with coronary heart disease (CHD) mortality. METHODS: A cohort analytic study carried out in a machinery factory in Xi'an, China on 1696 subjects aged 35 years or above (1124 men and 572 women) examined in 1976 and followed up till 2000. RESULTS: At baseline, the mean serum total cholesterol (TC) and triglyceride (TG) was 4.64 and 1.16 mmol/L in men, 4.62 and 1.10 mmol/L in women, respectively. Three hundred six (239 men, 67 women) had died within 37,781 person-years of follow-up, with 49 CHD deaths (36 male, 13 female). The relative risk (95% confidence interval) of CHD mortality per mmol/L increase in TG was 2.13 (1.46-3.17) after adjusting for age, marital status, occupation, education, systolic blood pressure and TC. Dose-response relationship between TG levels by tertiles and CHD risk was found. Stratified analyses showed TG was an independent predictor for CHD mortality in subjects with lower or higher TC. CONCLUSIONS: Chinese had lower levels of TC and TG than Western populations. This study provides new evidence that TG is an independent risk factor of CHD in subjects with lower or higher TC levels, and supports the lowering of cut-off value for elevated triglyceride. © 2003 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/86464
ISSN
2015 Impact Factor: 2.335
2015 SCImago Journal Rankings: 1.439
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHe, Yen_HK
dc.contributor.authorLam, THen_HK
dc.contributor.authorLi, LSen_HK
dc.contributor.authorLi, LSen_HK
dc.contributor.authorHe, SFen_HK
dc.contributor.authorLiang, BQen_HK
dc.date.accessioned2010-09-06T09:17:22Z-
dc.date.available2010-09-06T09:17:22Z-
dc.date.issued2004en_HK
dc.identifier.citationAnnals Of Epidemiology, 2004, v. 14 n. 1, p. 1-7en_HK
dc.identifier.issn1047-2797en_HK
dc.identifier.urihttp://hdl.handle.net/10722/86464-
dc.description.abstractPURPOSE: To study whether serum triglyceride (TG) was associated with coronary heart disease (CHD) mortality. METHODS: A cohort analytic study carried out in a machinery factory in Xi'an, China on 1696 subjects aged 35 years or above (1124 men and 572 women) examined in 1976 and followed up till 2000. RESULTS: At baseline, the mean serum total cholesterol (TC) and triglyceride (TG) was 4.64 and 1.16 mmol/L in men, 4.62 and 1.10 mmol/L in women, respectively. Three hundred six (239 men, 67 women) had died within 37,781 person-years of follow-up, with 49 CHD deaths (36 male, 13 female). The relative risk (95% confidence interval) of CHD mortality per mmol/L increase in TG was 2.13 (1.46-3.17) after adjusting for age, marital status, occupation, education, systolic blood pressure and TC. Dose-response relationship between TG levels by tertiles and CHD risk was found. Stratified analyses showed TG was an independent predictor for CHD mortality in subjects with lower or higher TC. CONCLUSIONS: Chinese had lower levels of TC and TG than Western populations. This study provides new evidence that TG is an independent risk factor of CHD in subjects with lower or higher TC levels, and supports the lowering of cut-off value for elevated triglyceride. © 2003 Elsevier Inc. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/annepidemen_HK
dc.relation.ispartofAnnals of Epidemiologyen_HK
dc.rightsAnnals of Epidemiology. Copyright © Elsevier Inc.en_HK
dc.subject.meshAdulten_HK
dc.subject.meshCause of Deathen_HK
dc.subject.meshChina - epidemiologyen_HK
dc.subject.meshCholesterol - blood - classificationen_HK
dc.subject.meshCoronary Disease - blood - mortalityen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshFollow-Up Studiesen_HK
dc.subject.meshHumansen_HK
dc.subject.meshIndustryen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshOccupational Healthen_HK
dc.subject.meshRisk Factorsen_HK
dc.subject.meshSex Factorsen_HK
dc.subject.meshSmoking - adverse effects - epidemiologyen_HK
dc.subject.meshStroke - mortalityen_HK
dc.subject.meshSurvival Analysisen_HK
dc.subject.meshTriglycerides - blood - classificationen_HK
dc.titleTriglyceride and coronary heart disease mortality in a 24-year follow-up study in Xi'an, Chinaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1047-2797&volume=14&spage=1&epage=7&date=2004&atitle=Triglyceride+and+coronary+heart+disease+mortality+in+a+24-year+follow-up+study+in+Xi%27an,+Chinaen_HK
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S1047-2797(03)00069-3en_HK
dc.identifier.pmid14664773-
dc.identifier.scopuseid_2-s2.0-0346851955en_HK
dc.identifier.hkuros85380en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0346851955&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume14en_HK
dc.identifier.issue1en_HK
dc.identifier.spage1en_HK
dc.identifier.epage7en_HK
dc.identifier.isiWOS:000187434900001-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridHe, Y=7404942229en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK
dc.identifier.scopusauthoridLi, LS=7501445194en_HK
dc.identifier.scopusauthoridLi, LS=26659754800en_HK
dc.identifier.scopusauthoridHe, SF=36800753400en_HK
dc.identifier.scopusauthoridLiang, BQ=36658723300en_HK

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