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Article: Intergenerational 'mismatch' and adiposity in a developing population: The Guangzhou biobank cohort study

TitleIntergenerational 'mismatch' and adiposity in a developing population: The Guangzhou biobank cohort study
Authors
Issue Date2010
PublisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/socscimed
Citation
Social Science And Medicine, 2010, v. 70 n. 6, p. 834-843 How to Cite?
AbstractIntergenerational 'mismatch' between maternal and adult environments, common in developing economies, has been hypothesized as contributing to obesity. In a rapidly developing population, we examined whether maternal conditions, proxied by maternal literacy, were associated with adult adiposity, proxied by body mass index (BMI) and waist-hip ratio (WHR) and whether these associations were modified by later life conditions, proxied by socio-economic position (SEP) at three life stages. We also examined if maternal conditions had sex-specific associations with adult adiposity. In a cross-sectional study of 19,957 adults (≥50 years) from the Guangzhou Biobank Cohort Study (phases 2 and 3 in 2005-2008), we used multivariable linear regression to assess the association of maternal literacy with BMI and WHR, and whether the associations varied with sex, age or SEP. The adjusted association of maternal literacy with WHR varied with sex. In women, but not men, maternal illiteracy was associated with higher WHR and BMI, adjusted for age; these associations remained, although attenuated, after adjusting for lifestyle, life course SEP and paternal literacy. There was little evidence that associations varied with SEP at any stage, although continuity of poor conditions into early life may have exacerbated the association of maternal illiteracy with higher WHR in women. Poor maternal conditions in developing populations may increase vulnerability to adiposity in women. Whether such sex-specific intergenerational effects are driven by epigenetics, maternal sex hormones or other mechanisms, remains to be determined. However, mismatched maternal and later life conditions do not appear to be associated with adiposity. Our findings, although preliminary, imply that a transient epidemic of obesity may occur in the first generation of women who experience economic development. © 2009 Elsevier Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/86433
ISSN
2015 Impact Factor: 2.814
2015 SCImago Journal Rankings: 1.894
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorKavikondala, Sen_HK
dc.contributor.authorJiang, CQen_HK
dc.contributor.authorZhang, WSen_HK
dc.contributor.authorCheng, KKen_HK
dc.contributor.authorLam, THen_HK
dc.contributor.authorLeung, GMen_HK
dc.contributor.authorSchooling, CMen_HK
dc.date.accessioned2010-09-06T09:16:58Z-
dc.date.available2010-09-06T09:16:58Z-
dc.date.issued2010en_HK
dc.identifier.citationSocial Science And Medicine, 2010, v. 70 n. 6, p. 834-843en_HK
dc.identifier.issn0277-9536en_HK
dc.identifier.urihttp://hdl.handle.net/10722/86433-
dc.description.abstractIntergenerational 'mismatch' between maternal and adult environments, common in developing economies, has been hypothesized as contributing to obesity. In a rapidly developing population, we examined whether maternal conditions, proxied by maternal literacy, were associated with adult adiposity, proxied by body mass index (BMI) and waist-hip ratio (WHR) and whether these associations were modified by later life conditions, proxied by socio-economic position (SEP) at three life stages. We also examined if maternal conditions had sex-specific associations with adult adiposity. In a cross-sectional study of 19,957 adults (≥50 years) from the Guangzhou Biobank Cohort Study (phases 2 and 3 in 2005-2008), we used multivariable linear regression to assess the association of maternal literacy with BMI and WHR, and whether the associations varied with sex, age or SEP. The adjusted association of maternal literacy with WHR varied with sex. In women, but not men, maternal illiteracy was associated with higher WHR and BMI, adjusted for age; these associations remained, although attenuated, after adjusting for lifestyle, life course SEP and paternal literacy. There was little evidence that associations varied with SEP at any stage, although continuity of poor conditions into early life may have exacerbated the association of maternal illiteracy with higher WHR in women. Poor maternal conditions in developing populations may increase vulnerability to adiposity in women. Whether such sex-specific intergenerational effects are driven by epigenetics, maternal sex hormones or other mechanisms, remains to be determined. However, mismatched maternal and later life conditions do not appear to be associated with adiposity. Our findings, although preliminary, imply that a transient epidemic of obesity may occur in the first generation of women who experience economic development. © 2009 Elsevier Ltd.en_HK
dc.languageengen_HK
dc.publisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/socscimeden_HK
dc.relation.ispartofSocial Science and Medicineen_HK
dc.subject.meshAdiposityen_HK
dc.subject.meshBody Mass Indexen_HK
dc.subject.meshChina - epidemiologyen_HK
dc.subject.meshCohort Studiesen_HK
dc.subject.meshCross-Sectional Studiesen_HK
dc.subject.meshDeveloping Countriesen_HK
dc.subject.meshEducational Statusen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHealth Status Disparitiesen_HK
dc.subject.meshHumansen_HK
dc.subject.meshLinear Modelsen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshMothers - statistics & numerical dataen_HK
dc.subject.meshMultivariate Analysisen_HK
dc.subject.meshObesity - epidemiologyen_HK
dc.subject.meshRisk Factorsen_HK
dc.subject.meshSex Factorsen_HK
dc.subject.meshSocial Classen_HK
dc.subject.meshWaist-Hip Ratioen_HK
dc.titleIntergenerational 'mismatch' and adiposity in a developing population: The Guangzhou biobank cohort studyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0277-9536&volume=70&issue=6&spage=834&epage=843&date=2010&atitle=Intergenerational+%27mismatch%27+and+adiposity+in+a+developing+population:+The+Guangzhou+biobank+cohort+studyen_HK
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_HK
dc.identifier.emailLeung, GM:gmleung@hku.hken_HK
dc.identifier.emailSchooling, CM:cms1@hkucc.hku.hken_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.identifier.authorityLeung, GM=rp00460en_HK
dc.identifier.authoritySchooling, CM=rp00504en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.socscimed.2009.11.009en_HK
dc.identifier.pmid20079564-
dc.identifier.scopuseid_2-s2.0-77950344187en_HK
dc.identifier.hkuros169078en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77950344187&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume70en_HK
dc.identifier.issue6en_HK
dc.identifier.spage834en_HK
dc.identifier.epage843en_HK
dc.identifier.isiWOS:000275971900007-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridKavikondala, S=14819602600en_HK
dc.identifier.scopusauthoridJiang, CQ=10639500500en_HK
dc.identifier.scopusauthoridZhang, WS=13410704100en_HK
dc.identifier.scopusauthoridCheng, KK=34876395100en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK
dc.identifier.scopusauthoridLeung, GM=7007159841en_HK
dc.identifier.scopusauthoridSchooling, CM=12808565000en_HK
dc.identifier.citeulike6554204-

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