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Article: Formation of apatite on poly(α-hydroxy acid) in an accelerated biomimetic process

TitleFormation of apatite on poly(α-hydroxy acid) in an accelerated biomimetic process
Authors
KeywordsAccelerated biomimetic process
Bonelike apatite
Poly(glycolic acid)
Poly(L-lactic acid)
Simulated body fluid
Issue Date2005
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0021-9304:1/
Citation
Journal Of Biomedical Materials Research - Part B Applied Biomaterials, 2005, v. 73 n. 1, p. 68-76 How to Cite?
AbstractBonelike apatite coating was formed on poly(L-lactic acid) films and poly(glycolic acid) scaffolds within 24 h through an accelerated biomimetic process. The ion concentrations in the simulated body fluid (SBF) were nearly 5 times of those in the human blood plasma. The apatite formed was characterized by using scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR). The apatite formed in 5SBFs was similar in morphology and composition to that formed in the classical biomimetic process using SBF or 1.5SBF and similar to that of natural bone. This indicated that the biomimetic apatite-coating process could be accelerated by using concentrated simulated body fluid at 37°C. Besides saving time, the accelerated biomimetic process is particularly significant to biodegradable polymers. Some polymers that degrade too fast to be coated with apatite by a classical biomimetic process (e.g., PGA) could be coated with bonelike apatite in an accelerated biomimetic process. © 2005 Wiley Periodicals, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/85443
ISSN
2004 Impact Factor: 3.652
2006 SCImago Journal Rankings: 0.474
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChen, Yen_HK
dc.contributor.authorMak, AFTen_HK
dc.contributor.authorLi, Jen_HK
dc.contributor.authorWang, Men_HK
dc.contributor.authorShum, AWTen_HK
dc.date.accessioned2010-09-06T09:04:51Z-
dc.date.available2010-09-06T09:04:51Z-
dc.date.issued2005en_HK
dc.identifier.citationJournal Of Biomedical Materials Research - Part B Applied Biomaterials, 2005, v. 73 n. 1, p. 68-76en_HK
dc.identifier.issn0021-9304en_HK
dc.identifier.urihttp://hdl.handle.net/10722/85443-
dc.description.abstractBonelike apatite coating was formed on poly(L-lactic acid) films and poly(glycolic acid) scaffolds within 24 h through an accelerated biomimetic process. The ion concentrations in the simulated body fluid (SBF) were nearly 5 times of those in the human blood plasma. The apatite formed was characterized by using scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR). The apatite formed in 5SBFs was similar in morphology and composition to that formed in the classical biomimetic process using SBF or 1.5SBF and similar to that of natural bone. This indicated that the biomimetic apatite-coating process could be accelerated by using concentrated simulated body fluid at 37°C. Besides saving time, the accelerated biomimetic process is particularly significant to biodegradable polymers. Some polymers that degrade too fast to be coated with apatite by a classical biomimetic process (e.g., PGA) could be coated with bonelike apatite in an accelerated biomimetic process. © 2005 Wiley Periodicals, Inc.en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0021-9304:1/en_HK
dc.relation.ispartofJournal of Biomedical Materials Research - Part B Applied Biomaterialsen_HK
dc.rightsJournal of Biomedical Materials Research Part B: Applied Biomaterials. Copyright © John Wiley & Sons, Inc.en_HK
dc.subjectAccelerated biomimetic processen_HK
dc.subjectBonelike apatiteen_HK
dc.subjectPoly(glycolic acid)en_HK
dc.subjectPoly(L-lactic acid)en_HK
dc.subjectSimulated body fluiden_HK
dc.subject.meshApatites - chemistry-
dc.subject.meshBiocompatible Materials - chemistry-
dc.subject.meshBone Substitutes - chemistry-
dc.subject.meshLactic Acid - chemistry-
dc.subject.meshPolyglycolic Acid - chemistry-
dc.titleFormation of apatite on poly(α-hydroxy acid) in an accelerated biomimetic processen_HK
dc.typeArticleen_HK
dc.identifier.emailWang, M:memwang@hku.hken_HK
dc.identifier.authorityWang, M=rp00185en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/jbm.b.30178en_HK
dc.identifier.pmid15672402-
dc.identifier.scopuseid_2-s2.0-16644390740en_HK
dc.identifier.hkuros98923en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-16644390740&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume73en_HK
dc.identifier.issue1en_HK
dc.identifier.spage68en_HK
dc.identifier.epage76en_HK
dc.identifier.isiWOS:000228076000010-
dc.publisher.placeNew York, United States-
dc.identifier.scopusauthoridChen, Y=8643007600en_HK
dc.identifier.scopusauthoridMak, AFT=35516744100en_HK
dc.identifier.scopusauthoridLi, J=7410064873en_HK
dc.identifier.scopusauthoridWang, M=15749714100en_HK
dc.identifier.scopusauthoridShum, AWT=8643007500en_HK

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