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Article: Molecular advances in severe acute respiratory syndrome-associated coronavirus (SARS-CoV).

TitleMolecular advances in severe acute respiratory syndrome-associated coronavirus (SARS-CoV).
Authors
Issue Date2003
PublisherKexue Chubanshe.
Citation
Genomics Proteomics Bioinformatics, 2003, v. 1 n. 4, p. 247-262 How to Cite?
Abstract
The sudden outbreak of severe acute respiratory syndrome (SARS) in 2002 prompted the establishment of a global scientific network subsuming most of the traditional rivalries in the competitive field of virology. Within months of the SARS outbreak, collaborative work revealed the identity of the disastrous pathogen as SARS-associated coronavirus (SARS-CoV). However, although the rapid identification of the agent represented an important breakthrough, our understanding of the deadly virus remains limited. Detailed biological knowledge is crucial for the development of effective countermeasures, diagnostic tests, vaccines and antiviral drugs against the SARS-CoV. This article reviews the present state of molecular knowledge about SARS-CoV, from the aspects of comparative genomics, molecular biology of viral genes, evolution, and epidemiology, and describes the diagnostic tests and the anti-viral drugs derived so far based on the available molecular information.
Persistent Identifierhttp://hdl.handle.net/10722/84886
ISSN
2013 SCImago Journal Rankings: 0.646

 

DC FieldValueLanguage
dc.contributor.authorChow, KYen_HK
dc.contributor.authorHon, CCen_HK
dc.contributor.authorHui, RKen_HK
dc.contributor.authorWong, RTen_HK
dc.contributor.authorYip, CWen_HK
dc.contributor.authorZeng, Fen_HK
dc.contributor.authorLeung, FCen_HK
dc.date.accessioned2010-09-06T08:58:16Z-
dc.date.available2010-09-06T08:58:16Z-
dc.date.issued2003en_HK
dc.identifier.citationGenomics Proteomics Bioinformatics, 2003, v. 1 n. 4, p. 247-262en_HK
dc.identifier.issn1672-0229en_HK
dc.identifier.urihttp://hdl.handle.net/10722/84886-
dc.description.abstractThe sudden outbreak of severe acute respiratory syndrome (SARS) in 2002 prompted the establishment of a global scientific network subsuming most of the traditional rivalries in the competitive field of virology. Within months of the SARS outbreak, collaborative work revealed the identity of the disastrous pathogen as SARS-associated coronavirus (SARS-CoV). However, although the rapid identification of the agent represented an important breakthrough, our understanding of the deadly virus remains limited. Detailed biological knowledge is crucial for the development of effective countermeasures, diagnostic tests, vaccines and antiviral drugs against the SARS-CoV. This article reviews the present state of molecular knowledge about SARS-CoV, from the aspects of comparative genomics, molecular biology of viral genes, evolution, and epidemiology, and describes the diagnostic tests and the anti-viral drugs derived so far based on the available molecular information.en_HK
dc.languageengen_HK
dc.publisherKexue Chubanshe.en_HK
dc.relation.ispartofGenomics Proteomics Bioinformaticsen_HK
dc.titleMolecular advances in severe acute respiratory syndrome-associated coronavirus (SARS-CoV).en_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1672-0229&volume=1&spage=247&epage=262&date=2003&atitle=Molecular+Advances+in+Severe+Acute+Respiratory+Syndrome-associated+Coronavirus+(SARS-CoV)en_HK
dc.identifier.emailHui, RK: rkhhui@hkucc.hku.hken_HK
dc.identifier.emailLeung, FC: fcleung@hkucc.hku.hken_HK
dc.identifier.authorityHui, RK=rp00711en_HK
dc.identifier.authorityLeung, FC=rp00731en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid15629054en_HK
dc.identifier.scopuseid_2-s2.0-13844281686en_HK
dc.identifier.hkuros85755en_HK
dc.identifier.volume1en_HK
dc.identifier.issue4en_HK
dc.identifier.spage247en_HK
dc.identifier.epage262en_HK
dc.publisher.placeChinaen_HK
dc.identifier.scopusauthoridChow, KY=7202180875en_HK
dc.identifier.scopusauthoridHon, CC=7003617137en_HK
dc.identifier.scopusauthoridHui, RK=7103304764en_HK
dc.identifier.scopusauthoridWong, RT=24759484000en_HK
dc.identifier.scopusauthoridYip, CW=7101665559en_HK
dc.identifier.scopusauthoridZeng, F=7202911544en_HK
dc.identifier.scopusauthoridLeung, FC=7103078633en_HK

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