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Article: Genomic growth hormone gene polymorphisms in native Chinese chickens

TitleGenomic growth hormone gene polymorphisms in native Chinese chickens
Authors
Issue Date2001
PublisherRoyal Society of Medicine Press Ltd.. The Journal's web site is located at http://www.ebm.rsmjournals.com
Citation
Experimental Biology and Medicine, 2001, v. 226 n. 5, p. 458-462 How to Cite?
AbstractChicken growth hormone (cGH), a polypeptide hormone synthesized in and secreted by the pituitary gland, is involved in a wide variety of physiological functions such as growth, body composition, egg production, aging, and reproduction. Chicken growth hormone polymorphisms have been reported to be associated with certain phenotypes. Our objective is to investigate the GH gene polymorphism in selected strains of native Chinese chickens. Yellow Wai Chow GH gene was characterized by sequencing and was found to have one silent substitution, 31 insertions, and other substitutions spread among the introns. In addition, a novel Mspl site has been identified and characterized in the first intron. Allele frequencies of the intron 1 polymorphism were characterized among 28 populations of native Chinese chickens. Thus, polymorphism of the cGH gene may be useful in phylogenetic analysis, as well as in the design of breeding programs.
Persistent Identifierhttp://hdl.handle.net/10722/84863
ISSN
2015 Impact Factor: 2.542
2015 SCImago Journal Rankings: 0.991
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorIp, SCYen_HK
dc.contributor.authorZhang, Xen_HK
dc.contributor.authorLeung, FCCen_HK
dc.date.accessioned2010-09-06T08:58:00Z-
dc.date.available2010-09-06T08:58:00Z-
dc.date.issued2001en_HK
dc.identifier.citationExperimental Biology and Medicine, 2001, v. 226 n. 5, p. 458-462en_HK
dc.identifier.issn1535-3702en_HK
dc.identifier.urihttp://hdl.handle.net/10722/84863-
dc.description.abstractChicken growth hormone (cGH), a polypeptide hormone synthesized in and secreted by the pituitary gland, is involved in a wide variety of physiological functions such as growth, body composition, egg production, aging, and reproduction. Chicken growth hormone polymorphisms have been reported to be associated with certain phenotypes. Our objective is to investigate the GH gene polymorphism in selected strains of native Chinese chickens. Yellow Wai Chow GH gene was characterized by sequencing and was found to have one silent substitution, 31 insertions, and other substitutions spread among the introns. In addition, a novel Mspl site has been identified and characterized in the first intron. Allele frequencies of the intron 1 polymorphism were characterized among 28 populations of native Chinese chickens. Thus, polymorphism of the cGH gene may be useful in phylogenetic analysis, as well as in the design of breeding programs.-
dc.languageengen_HK
dc.publisherRoyal Society of Medicine Press Ltd.. The Journal's web site is located at http://www.ebm.rsmjournals.comen_HK
dc.relation.ispartofExperimental Biology and Medicineen_HK
dc.subject.meshAlleles-
dc.subject.meshAnimals-
dc.subject.meshChickens - genetics-
dc.subject.meshGrowth Hormone - genetics-
dc.subject.meshPolymorphism, Genetic-
dc.titleGenomic growth hormone gene polymorphisms in native Chinese chickensen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1535-3702&volume=226&issue=5&spage=458&epage=462&date=2001&atitle=Genomic+growth+hormone+gene+polymorphisms+in+native+Chinese+chickensen_HK
dc.identifier.emailLeung, FCC: fcleung@hkucc.hku.hken_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.pmid11393175-
dc.identifier.hkuros66135en_HK
dc.identifier.volume226-
dc.identifier.issue5-
dc.identifier.spage458-
dc.identifier.epage462-
dc.identifier.isiWOS:000168542500011-

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