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Article: Evidence for recombination in natural populations of porcine circovirus type 2 in Hong Kong and mainland China

TitleEvidence for recombination in natural populations of porcine circovirus type 2 in Hong Kong and mainland China
Authors
Issue Date2007
PublisherSociety for General Microbiology. The Journal's web site is located at http://vir.sgmjournals.org
Citation
Journal Of General Virology, 2007, v. 88 n. 6, p. 1733-1737 How to Cite?
AbstractPorcine circovirus type 2 (PCV2) belongs to the family Circoviridae, and is the causative agent of post-weaning multisystemic wasting syndrome (PMWS) in pigs. In this study, phylogenetic analyses of three complete PCV2 genomic sequences from Hong Kong suggest that natural recombination happened among different lineages of PCV2. A preliminary investigation of the parental strains of these potential recombinants was carried out using bootscanning. Statistical significance of this recombination event was tested and positions of the potential recombination breakpoints were estimated in a maximum-likelihood framework. The recombinant breakpoints were estimated to be located within the origin of replication (ori) and replicase (rep) gene of PCV2. Interestingly, several GenBank sequences of PCV2 in mainland China were found to have a recombination pattern similar to that of the potential PCV2 recombinants from Hong Kong, implying that this recombinant genotype might already be widespread within mainland China. © 2007 SGM.
Persistent Identifierhttp://hdl.handle.net/10722/84844
ISSN
2015 Impact Factor: 3.192
2015 SCImago Journal Rankings: 1.741
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorMa, CMen_HK
dc.contributor.authorHon, CCen_HK
dc.contributor.authorLam, TYen_HK
dc.contributor.authorLi, VYYen_HK
dc.contributor.authorWong, CKWen_HK
dc.contributor.authorde Oliveira, Ten_HK
dc.contributor.authorLeung, FCCen_HK
dc.date.accessioned2010-09-06T08:57:46Z-
dc.date.available2010-09-06T08:57:46Z-
dc.date.issued2007en_HK
dc.identifier.citationJournal Of General Virology, 2007, v. 88 n. 6, p. 1733-1737en_HK
dc.identifier.issn0022-1317en_HK
dc.identifier.urihttp://hdl.handle.net/10722/84844-
dc.description.abstractPorcine circovirus type 2 (PCV2) belongs to the family Circoviridae, and is the causative agent of post-weaning multisystemic wasting syndrome (PMWS) in pigs. In this study, phylogenetic analyses of three complete PCV2 genomic sequences from Hong Kong suggest that natural recombination happened among different lineages of PCV2. A preliminary investigation of the parental strains of these potential recombinants was carried out using bootscanning. Statistical significance of this recombination event was tested and positions of the potential recombination breakpoints were estimated in a maximum-likelihood framework. The recombinant breakpoints were estimated to be located within the origin of replication (ori) and replicase (rep) gene of PCV2. Interestingly, several GenBank sequences of PCV2 in mainland China were found to have a recombination pattern similar to that of the potential PCV2 recombinants from Hong Kong, implying that this recombinant genotype might already be widespread within mainland China. © 2007 SGM.en_HK
dc.languageengen_HK
dc.publisherSociety for General Microbiology. The Journal's web site is located at http://vir.sgmjournals.orgen_HK
dc.relation.ispartofJournal of General Virologyen_HK
dc.titleEvidence for recombination in natural populations of porcine circovirus type 2 in Hong Kong and mainland Chinaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-1317&volume=88&spage=1733&epage=1737&date=2007&atitle=Evidence+for+recombination+in+natural+populations+of+porcine+circovirus+type+2+in+Hong+Kong+and+mainland+Chinaen_HK
dc.identifier.emailLeung, FCC: fcleung@hkucc.hku.hken_HK
dc.identifier.authorityLeung, FCC=rp00731en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1099/vir.0.82629-0en_HK
dc.identifier.pmid17485533-
dc.identifier.scopuseid_2-s2.0-34249787861en_HK
dc.identifier.hkuros133516en_HK
dc.identifier.hkuros255013-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34249787861&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume88en_HK
dc.identifier.issue6en_HK
dc.identifier.spage1733en_HK
dc.identifier.epage1737en_HK
dc.identifier.isiWOS:000247087900011-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridMa, CM=15062956500en_HK
dc.identifier.scopusauthoridHon, CC=7003617137en_HK
dc.identifier.scopusauthoridLam, TY=14527268100en_HK
dc.identifier.scopusauthoridLi, VYY=7202621838en_HK
dc.identifier.scopusauthoridWong, CKW=36862854100en_HK
dc.identifier.scopusauthoridde Oliveira, T=8897715800en_HK
dc.identifier.scopusauthoridLeung, FCC=7103078633en_HK

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