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Article: Apoptosis in mouse peritoneal macrophages induced by oxidised low-density lipoprotein and prevention by the polysaccharide kreskin
Title | Apoptosis in mouse peritoneal macrophages induced by oxidised low-density lipoprotein and prevention by the polysaccharide kreskin |
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Authors | |
Keywords | Apoptosis DNA ladder Kreskin Oxidised low-density lipoprotein Peritoneal macrophage Polysaccharide |
Issue Date | 1997 |
Publisher | Chapman & Hall, Journals Department. The Journal's web site is located at http://www.chaphall.com/chaphall/journals.html |
Citation | Medical Science Research, 1997, v. 25 n. 6, p. 429-431 How to Cite? |
Abstract | Exposure of mouse peritoneal macrophages (MPM) to oxidised low-density lipoprotein (Ox-LDL) induced apoptosis, characterised by DNA fragmentation with a classical ladder pattern and chromatin condensation. Exposure of MPM to native LDL and acetylated LDL did not do so. DNA fragmentation caused by Ox-LDL was dependent on concentration and time. The polysaccharide kreskin, injected peritoneally into mice, protected their macrophages from apoptosis caused by Ox-LDL. |
Persistent Identifier | http://hdl.handle.net/10722/84600 |
ISSN | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Liu, SX | en_HK |
dc.contributor.author | Zhou, M | en_HK |
dc.contributor.author | Chen, Y | en_HK |
dc.contributor.author | Wen, WY | en_HK |
dc.contributor.author | Wan, J | en_HK |
dc.date.accessioned | 2010-09-06T08:54:55Z | - |
dc.date.available | 2010-09-06T08:54:55Z | - |
dc.date.issued | 1997 | en_HK |
dc.identifier.citation | Medical Science Research, 1997, v. 25 n. 6, p. 429-431 | en_HK |
dc.identifier.issn | 0269-8951 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/84600 | - |
dc.description.abstract | Exposure of mouse peritoneal macrophages (MPM) to oxidised low-density lipoprotein (Ox-LDL) induced apoptosis, characterised by DNA fragmentation with a classical ladder pattern and chromatin condensation. Exposure of MPM to native LDL and acetylated LDL did not do so. DNA fragmentation caused by Ox-LDL was dependent on concentration and time. The polysaccharide kreskin, injected peritoneally into mice, protected their macrophages from apoptosis caused by Ox-LDL. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Chapman & Hall, Journals Department. The Journal's web site is located at http://www.chaphall.com/chaphall/journals.html | en_HK |
dc.relation.ispartof | Medical Science Research | en_HK |
dc.subject | Apoptosis | en_HK |
dc.subject | DNA ladder | en_HK |
dc.subject | Kreskin | en_HK |
dc.subject | Oxidised low-density lipoprotein | en_HK |
dc.subject | Peritoneal macrophage | en_HK |
dc.subject | Polysaccharide | en_HK |
dc.title | Apoptosis in mouse peritoneal macrophages induced by oxidised low-density lipoprotein and prevention by the polysaccharide kreskin | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0269-8951&volume=25&spage=429&epage=437&date=1997&atitle=Apoptosis+in+mouse+peritoneal+macrophages+induced+by+oxidized+low-density+lipoprotein+and+prevention+by+the+polysaccharide+kreskin | en_HK |
dc.identifier.email | Wan, J: jmfwan@hku.hk | en_HK |
dc.identifier.authority | Wan, J=rp00798 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.scopus | eid_2-s2.0-0030845099 | en_HK |
dc.identifier.hkuros | 35642 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0030845099&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 25 | en_HK |
dc.identifier.issue | 6 | en_HK |
dc.identifier.spage | 429 | en_HK |
dc.identifier.epage | 431 | en_HK |
dc.publisher.place | United Kingdom | en_HK |
dc.identifier.scopusauthorid | Liu, SX=7409463469 | en_HK |
dc.identifier.scopusauthorid | Zhou, M=7403506134 | en_HK |
dc.identifier.scopusauthorid | Chen, Y=16745998900 | en_HK |
dc.identifier.scopusauthorid | Wen, WY=7102170594 | en_HK |
dc.identifier.scopusauthorid | Wan, J=8930305000 | en_HK |
dc.identifier.issnl | 0269-8951 | - |