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Article: Surgical therapy of hepatocellular carcinoma in the cirrhotic liver

TitleSurgical therapy of hepatocellular carcinoma in the cirrhotic liver
Authors
KeywordsCirrhosis
Hepatocellular carcinoma
Issue Date1999
PublisherSchweizerische Gesellschaft fuer Chirurgie.
Citation
Swiss Surgery, 1999, v. 5 n. 3, p. 107-110 How to Cite?
AbstractHepatectomy for hepatocellular carcinoma (HCC) associated with cirrhosis was considered by some surgeons contraindicated because the hospital mortality rate, especially for major hepatectomy, was very high. The author reported his surgical approach to hepatectomy associated with cirrhosis. Between 1989 and 1995, 66 major hepatectomies and 32 minor hepatectomies were performed in 98 cirrhotic patients. The selection of patients for hepatectomy was based on results of indocyanine green clearance test. The surgical technique was designed to reduce blood loss, ischaemic injury to the liver remnant and preservation of liver parenchyma. The postoperative care was designed to maintain or improve liver function. By such an approach the hospital mortality rate of the cirrhotic patients having hepatectomy decreased from 40% in 1989 to 5% in 1995. The 5-year survival rate also improved to 41.2%, which is not statistically different from that of those with a normal liver or chronic hepatitis. With refinement in surgical technique and perioperative care, patients with cirrhosis can also benefit from hepatectomy for HCC.
Persistent Identifierhttp://hdl.handle.net/10722/84580
ISSN
2006 SCImago Journal Rankings: 0.113
References

 

DC FieldValueLanguage
dc.contributor.authorFan, STen_HK
dc.date.accessioned2010-09-06T08:54:37Z-
dc.date.available2010-09-06T08:54:37Z-
dc.date.issued1999en_HK
dc.identifier.citationSwiss Surgery, 1999, v. 5 n. 3, p. 107-110en_HK
dc.identifier.issn1023-9332en_HK
dc.identifier.urihttp://hdl.handle.net/10722/84580-
dc.description.abstractHepatectomy for hepatocellular carcinoma (HCC) associated with cirrhosis was considered by some surgeons contraindicated because the hospital mortality rate, especially for major hepatectomy, was very high. The author reported his surgical approach to hepatectomy associated with cirrhosis. Between 1989 and 1995, 66 major hepatectomies and 32 minor hepatectomies were performed in 98 cirrhotic patients. The selection of patients for hepatectomy was based on results of indocyanine green clearance test. The surgical technique was designed to reduce blood loss, ischaemic injury to the liver remnant and preservation of liver parenchyma. The postoperative care was designed to maintain or improve liver function. By such an approach the hospital mortality rate of the cirrhotic patients having hepatectomy decreased from 40% in 1989 to 5% in 1995. The 5-year survival rate also improved to 41.2%, which is not statistically different from that of those with a normal liver or chronic hepatitis. With refinement in surgical technique and perioperative care, patients with cirrhosis can also benefit from hepatectomy for HCC.en_HK
dc.languageengen_HK
dc.publisherSchweizerische Gesellschaft fuer Chirurgie.en_HK
dc.relation.ispartofSwiss Surgeryen_HK
dc.subjectCirrhosisen_HK
dc.subjectHepatocellular carcinomaen_HK
dc.titleSurgical therapy of hepatocellular carcinoma in the cirrhotic liveren_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1023-9332&volume=5&spage=107&epage=110&date=1999&atitle=Surgical+therapy+of+hepatocellular+carcinoma+in+the+cirrhotic+liveren_HK
dc.identifier.emailFan, ST: stfan@hku.hken_HK
dc.identifier.authorityFan, ST=rp00355en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid10414180-
dc.identifier.scopuseid_2-s2.0-0032588538en_HK
dc.identifier.hkuros40793en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032588538&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume5en_HK
dc.identifier.issue3en_HK
dc.identifier.spage107en_HK
dc.identifier.epage110en_HK
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridFan, ST=7402678224en_HK

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