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Article: Life-threatening cryoglobulinemia in HCV-negative Southern Chinese and a novel association with structural aortic abnormalities

TitleLife-threatening cryoglobulinemia in HCV-negative Southern Chinese and a novel association with structural aortic abnormalities
Authors
KeywordsChinese
Cryoglobulin
HBV
Malignancy
Structural aortic abnormality
Issue Date2005
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00277/index.htm
Citation
Annals Of Hematology, 2005, v. 84 n. 2, p. 95-98 How to Cite?
AbstractCryoglobulinemia is uncommon in Southern Chinese in Hong Kong, with tropical climates and low incidence of hepatitis C virus (HCV) infection. Eight positive cases were detected among 481 patients screened for cryoglobulins over a 10-year period. Three HCV carriers (38%) ran benign courses. The others included two carriers of hepatitis B virus (HBV), two patients with adenocarcinoma, and one with chronic lymphocytic lymphoma. Four of them (except one HBV carrier) ran fulminant courses and died of cryoglobulin-related complications. Interestingly, all four cases also had structural aortic abnormalities, including multiple dissections, aneurysms, and congenital aortic arch abnormalities, which were often life threatening. The association of aortic abnormality and cryoglobulinemia is hitherto unreported and may be peculiar to our ethnic group. Aggressive control of the cryoglobulin may help to reduce aortic intima damage. © Springer-Verlag 2005.
Persistent Identifierhttp://hdl.handle.net/10722/84526
ISSN
2015 Impact Factor: 3.022
2015 SCImago Journal Rankings: 1.117
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorAu, WYen_HK
dc.contributor.authorKwok, JSYen_HK
dc.contributor.authorChu, KMen_HK
dc.contributor.authorMa, ESKen_HK
dc.date.accessioned2010-09-06T08:53:59Z-
dc.date.available2010-09-06T08:53:59Z-
dc.date.issued2005en_HK
dc.identifier.citationAnnals Of Hematology, 2005, v. 84 n. 2, p. 95-98en_HK
dc.identifier.issn0939-5555en_HK
dc.identifier.urihttp://hdl.handle.net/10722/84526-
dc.description.abstractCryoglobulinemia is uncommon in Southern Chinese in Hong Kong, with tropical climates and low incidence of hepatitis C virus (HCV) infection. Eight positive cases were detected among 481 patients screened for cryoglobulins over a 10-year period. Three HCV carriers (38%) ran benign courses. The others included two carriers of hepatitis B virus (HBV), two patients with adenocarcinoma, and one with chronic lymphocytic lymphoma. Four of them (except one HBV carrier) ran fulminant courses and died of cryoglobulin-related complications. Interestingly, all four cases also had structural aortic abnormalities, including multiple dissections, aneurysms, and congenital aortic arch abnormalities, which were often life threatening. The association of aortic abnormality and cryoglobulinemia is hitherto unreported and may be peculiar to our ethnic group. Aggressive control of the cryoglobulin may help to reduce aortic intima damage. © Springer-Verlag 2005.en_HK
dc.languageengen_HK
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00277/index.htmen_HK
dc.relation.ispartofAnnals of Hematologyen_HK
dc.subjectChineseen_HK
dc.subjectCryoglobulinen_HK
dc.subjectHBVen_HK
dc.subjectMalignancyen_HK
dc.subjectStructural aortic abnormalityen_HK
dc.titleLife-threatening cryoglobulinemia in HCV-negative Southern Chinese and a novel association with structural aortic abnormalitiesen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0939-5555&volume=84&spage=95&epage=98&date=2005&atitle=Life-threatening+cryoglobulinemia+in+HCV+negative+Southern+Chinese+and+a+novel+association+with+structural+aortic+abnormalitiesen_HK
dc.identifier.emailChu, KM: chukm@hkucc.hku.hken_HK
dc.identifier.authorityChu, KM=rp00435en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00277-004-0955-7en_HK
dc.identifier.pmid15503020-
dc.identifier.scopuseid_2-s2.0-11844259436en_HK
dc.identifier.hkuros97203en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-11844259436&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume84en_HK
dc.identifier.issue2en_HK
dc.identifier.spage95en_HK
dc.identifier.epage98en_HK
dc.identifier.isiWOS:000226119100006-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridAu, WY=7202383089en_HK
dc.identifier.scopusauthoridKwok, JSY=7006208874en_HK
dc.identifier.scopusauthoridChu, KM=7402453538en_HK
dc.identifier.scopusauthoridMa, ESK=7202039934en_HK

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