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Article: Malignancy associated with hepatolithiasis

TitleMalignancy associated with hepatolithiasis
Authors
KeywordsCholangiocarcinoma
Hepatic resection
Hepatolithiasis
Issue Date1997
PublisherHepato-Gastroenterology. The Journal's web site is located at http://www.thieme.de/hepato/index.html
Citation
Hepato-Gastroenterology, 1997, v. 44 n. 14, p. 352-357 How to Cite?
AbstractBackground/Aims: Malignancy is known to be associated with hepatolithiasis. The present report summarizes the results of our management of patients with cholangiocarcinoma associated with hepatolithiasis. Materials and Methods: Twenty patients with cholangiocarcinoma and associated hepatolithiasis were analyzed retrospectively. There were 12 males and 8 females, with a mean, age of 59.3 years. The clinical records of these patients were reviewed to determine demographic characteristics, clinical features, laboratory findings, diagnostic tests, operative management and results of therapy. Results: One patient was moribund on presentation and was treated conservatively. Fourteen patients underwent hepatic resection. Three of them had palliative resection. Hepatic resection was less likely to be performed in patients having right lobe disease (50%) as compared to patients having left lobe disease (90%) (p = NS). The overall operative morbidity and mortality rates after hepatic resection were 36% and 7%, respectively. Non-resective operations were performed in five patients. The overall operative morbidity and mortality rates after non-resective operations were 20% and 0%, respectively. After curative hepatic resection (11 patients), the 1- and 2-year survival rates were 81% and 51%, respectively. Conclusion: A suspicion of malignancy is necessary in managing patients with hepatolithiasis. Hepatic resection is the treatment of choice for cholangiocarcinoma when it is resectable.
Persistent Identifierhttp://hdl.handle.net/10722/84478
ISSN
2015 Impact Factor: 0.792
2015 SCImago Journal Rankings: 0.446
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChu, KMen_HK
dc.contributor.authorLo, CMen_HK
dc.contributor.authorLiu, CLen_HK
dc.contributor.authorFan, STen_HK
dc.date.accessioned2010-09-06T08:53:26Z-
dc.date.available2010-09-06T08:53:26Z-
dc.date.issued1997en_HK
dc.identifier.citationHepato-Gastroenterology, 1997, v. 44 n. 14, p. 352-357en_HK
dc.identifier.issn0172-6390en_HK
dc.identifier.urihttp://hdl.handle.net/10722/84478-
dc.description.abstractBackground/Aims: Malignancy is known to be associated with hepatolithiasis. The present report summarizes the results of our management of patients with cholangiocarcinoma associated with hepatolithiasis. Materials and Methods: Twenty patients with cholangiocarcinoma and associated hepatolithiasis were analyzed retrospectively. There were 12 males and 8 females, with a mean, age of 59.3 years. The clinical records of these patients were reviewed to determine demographic characteristics, clinical features, laboratory findings, diagnostic tests, operative management and results of therapy. Results: One patient was moribund on presentation and was treated conservatively. Fourteen patients underwent hepatic resection. Three of them had palliative resection. Hepatic resection was less likely to be performed in patients having right lobe disease (50%) as compared to patients having left lobe disease (90%) (p = NS). The overall operative morbidity and mortality rates after hepatic resection were 36% and 7%, respectively. Non-resective operations were performed in five patients. The overall operative morbidity and mortality rates after non-resective operations were 20% and 0%, respectively. After curative hepatic resection (11 patients), the 1- and 2-year survival rates were 81% and 51%, respectively. Conclusion: A suspicion of malignancy is necessary in managing patients with hepatolithiasis. Hepatic resection is the treatment of choice for cholangiocarcinoma when it is resectable.en_HK
dc.languageengen_HK
dc.publisherHepato-Gastroenterology. The Journal's web site is located at http://www.thieme.de/hepato/index.htmlen_HK
dc.relation.ispartofHepato-Gastroenterologyen_HK
dc.subjectCholangiocarcinomaen_HK
dc.subjectHepatic resectionen_HK
dc.subjectHepatolithiasisen_HK
dc.titleMalignancy associated with hepatolithiasisen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0172-6390&volume=44&spage=352&epage=357&date=1997&atitle=Malignancy+associated+with+hepatolithiasisen_HK
dc.identifier.emailChu, KM: chukm@hkucc.hku.hken_HK
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hken_HK
dc.identifier.emailFan, ST: stfan@hku.hken_HK
dc.identifier.authorityChu, KM=rp00435en_HK
dc.identifier.authorityLo, CM=rp00412en_HK
dc.identifier.authorityFan, ST=rp00355en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid9164501-
dc.identifier.scopuseid_2-s2.0-0030897891en_HK
dc.identifier.hkuros22236en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0030897891&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume44en_HK
dc.identifier.issue14en_HK
dc.identifier.spage352en_HK
dc.identifier.epage357en_HK
dc.identifier.isiWOS:A1997WV91700008-
dc.publisher.placeGreeceen_HK
dc.identifier.scopusauthoridChu, KM=7402453538en_HK
dc.identifier.scopusauthoridLo, CM=7401771672en_HK
dc.identifier.scopusauthoridLiu, CL=7409789712en_HK
dc.identifier.scopusauthoridFan, ST=7402678224en_HK

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